Evidence map›Paper›PMID 30016880›Full record

ArticleChronic respiratory disease

Inhaler usability of a pressurized metered dose inhaler and a soft mist inhaler in patients with COPD: A simulated-use study.

Bo Ding, Shahid Siddiqui, Michael DePietro, Gunilla Petersson, Ubaldo J Martin

Open access · goldAbstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Chronic respiratory disease. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 3 pooled it
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 3 syntheses or guidelines pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. The Role of the Pharmacist in Inhaler Selection and Education in Chronic Obstructive Pulmonary Disease.The Journal of pharmacy technology : jPT : official publication of the Association of Pharmacy Technicians · 2021
    Review
  6. Review
  7. Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Bo Ding1 AstraZeneca Gothenburg, Mölndal, Sweden.
Shahid Siddiqui2 AstraZeneca, Gaithersburg, MD, USA.
Michael DePietro2 AstraZeneca, Gaithersburg, MD, USA.ORCID 0000-0002-8729-2530
Gunilla Petersson1 AstraZeneca Gothenburg, Mölndal, Sweden.
Ubaldo J Martin2 AstraZeneca, Gaithersburg, MD, USA.
AstraZeneca (United States) · USAstraZeneca (Sweden) · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The objective of this study was to evaluate task performance and handling errors with soft mist inhalers (SMIs) or pressurized metered-dose inhalers (pMDIs) among patients with chronic obstructive pulmonary disease (COPD) experienced with, but not recently trained in, using these devices. This exploratory, noninterventional, simulated-use study (D5970R00004) assessed handling/usability of SMIs and pMDIs in inhaler-experienced patients with COPD (40-78 years; diagnosis ≥6 months). Patients received a device and instruction-for-use leaflet but no training and were recorded while performing tasks required for checking the device, priming, and dosing. Errors that could substantially affect the lung-delivered dose were considered critical. Sixteen of 61 patients (52% male) had used SMIs and 55 had used pMDIs. Thirty-one patients received an SMI and 30 a pMDI. Overall, 79% made ≥5 performance errors (SMI 94%; pMDI 63%) and 49% made ≥5 critical errors (SMI 68%; pMDI 30%). All patients made ≥1 error; three (all pMDI) made no critical errors. Regardless of the device used and previous inhaler experience, patient-centered training, education, and continuous retraining on correct inhaler use should be key aspects of routine patient care in COPD.

Indexed as

Patient ComplianceAdministration, InhalationAdultAgedAged, 80 and overBronchodilator AgentsDose-Response Relationship, DrugEquipment DesignFemaleFollow-Up StudiesHumansMaleMetered Dose InhalersMiddle AgedPulmonary Disease, Chronic ObstructiveRetrospective StudiesBronchodilator Agentsbronchodilator agentsChronic obstructive pulmonary diseaseinhalationmetered dose inhalerspatient compliancesoft mist inhalers

Identifiers

PMID30016880
PMCPMC6302969
OpenAlexW2883198845

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.