Evidence map›Paper›PMID 30016586›Full record

ArticleJournal of agricultural and food chemistry2018

Isolation and Identification of Tyrosinase-Inhibitory and Copper-Chelating Peptides from Hydrolyzed Rice-Bran-Derived Albumin.

Supatcha Kubglomsong, Chockchai Theerakulkait, Ralph L Reed, Liping Yang, Claudia S Maier, Jan F Stevens

Open access · greenAbstract read
In one paragraph

Article in Journal of agricultural and food chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 93 citations in OpenAlex.

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  9. Applications of bioactive peptides in cosmeceuticals: a review.Journal of Zhejiang University. Science. B · 2025
    Review
  10. Usage Frequency and Ecotoxicity of Skin Depigmenting Agents.Pharmaceuticals (Basel, Switzerland) · 2025
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  17. Anti-Melanogenic Effects ofMarine drugs · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Supatcha KubglomsongSchool of Human Ecology (Program in Food, Nutrition and Applications) , Sukhothai Thammathirat Open University , Chaengwattana Road , Bangpood, Pakkret , Nonthaburi 11120 , Thailand.
Chockchai TheerakulkaitDepartment of Food Science and Technology, Faculty of Agro-Industry , Kasetsart University , Chatuchak, Bangkok 10900 , Thailand.ORCID http://orcid.org/0000-0002-1385-0229
Ralph L ReedDepartment of Pharmaceutical Sciences, College of Pharmacy and the Linus Pauling Institute , Oregon State University , Corvallis , Oregon 97331 , United States.
Liping YangDepartment of Chemistry , Oregon State University , Corvallis , Oregon 97331 , United States.
Claudia S MaierDepartment of Chemistry , Oregon State University , Corvallis , Oregon 97331 , United States.
Jan F StevensDepartment of Pharmaceutical Sciences, College of Pharmacy and the Linus Pauling Institute , Oregon State University , Corvallis , Oregon 97331 , United States.
Oregon State University · USKasetsart University · THSukhothai Thammathirat Open University · TH

Funding

Orbitrap Elite with ETDS10OD020111 · OD · OREGON STATE UNIVERSITY · PI MAIER, CLAUDIA S · 2015 to 2015
$600k
NIH HHS S10 OD020111
6 · The paper itself

Abstract

Rice-bran albumin (RBAlb), which shows higher tyrosinase-inhibitory activity than other protein fractions, was hydrolyzed with papain to improve the bioactivity. The obtained RBAlb hydrolysate (RBAlbH) was separated into 11 peptide fractions by RP-HPLC. Tyrosinase inhibition and copper chelation activities decreased with increasing retention times of the peptide fractions. RBAlbH fraction 1, which exhibited the greatest activity, contained 13 peptides whose sequences were determined by using LC-MS/MS. Most of the peptide sequences contained features of previously reported tyrosinase-inhibitory and metal-chelating peptides, especially peptide SSEYYGGEGSSSEQGYYGEG. RBAlbH fraction 1 showed more effective tyrosinase inhibition (IC

Indexed as

CopperAlbuminsAmino Acid SequenceChelating AgentsEnzyme InhibitorsHydrolysisMonophenol MonooxygenaseOryzaPeptidesPlant ProteinsSeedsAlbuminsChelating AgentsCopperEnzyme InhibitorsMonophenol MonooxygenasePeptidesPlant Proteinscopper chelationenzymatic hydrolysatesrice-bran albumintyrosinase inhibition

Identifiers

PMID30016586
PMCPMC6431294
OpenAlexW2883277828

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.