Evidence map›Paper›PMID 30016463›Full record

ArticlePain medicine (Malden, Mass.)2019

Bidirectionality of Pain Interference and PTSD Symptoms in Military Veterans: Does Injury Status Moderate Effects?

Sharon Y Lee, Lucy Finkelstein-Fox, Crystal L Park, Carolyn M Mazure, Tania B Huedo-Medina, Rani Hoff

Open access · greenAbstract read
In one paragraph

Article in Pain medicine (Malden, Mass.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 16 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Article
  4. Article
  5. Observational
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Sharon Y LeeDepartment of Psychological Sciences, University of Connecticut, Storrs, CT, USA.
Lucy Finkelstein-FoxDepartment of Psychological Sciences, University of Connecticut, Storrs, CT, USA.
Crystal L ParkDepartment of Psychological Sciences, University of Connecticut, Storrs, CT, USA.
Carolyn M MazureDepartment of Psychiatry, Yale University School of Medicine, New Haven, CT, USA.
Tania B Huedo-MedinaDepartment of Allied Health, University of Connecticut, Storrs, CT, USA.
Rani HoffDepartment of Psychiatry, Yale University School of Medicine, New Haven, CT, USA.
University of Connecticut · USYale University · US

Funding

Yale SCOR on Gender-Sensitive Treatment for Tobacco DependenceP50DA033945 · NIDA · YALE UNIVERSITY · PI MCKEE, SHERRY ANN · 2012 to 2017
$6.5M
NIDA NIH HHS P50 DA033945
6 · The paper itself

Abstract

objectivePain and post-traumatic stress disorder (PTSD) symptoms are strongly correlated in veteran populations. Arguments for which one condition predicts or worsens the other condition have gone in both directions. However, research addressing this issue has been primarily limited to cross-sectional studies rather than examinations of a potential bidirectional relationship between pain interference and PTSD symptoms over time. In addition, no studies have examined deployment injury status as potentially moderating this bidirectional effect in veterans. To address these gaps in the literature, the present longitudinal study examined whether there is a bidirectional relationship between pain interference and PTSD symptoms in a sample of male and female veterans returning from Operation Iraqi Freedom, Operation Enduring Freedom, or Operation New Dawn (N = 729) and whether deployment injury status moderates this relationship.

methodsParticipants completed phone interviews regarding pain interference and PTSD symptoms at three time points, each three months apart.

resultsPain interference at Time 1 predicted worse PTSD symptoms at Time 2 for the subset of veterans who sustained injuries during deployment (n = 381) but not for veterans with pain interference who did not sustain injuries (n = 338). From Time 1 to Time 3, elevations in PTSD symptoms were mediated by pain interference for injured veterans; in contrast, PTSD symptoms did not appear to drive changes in pain interference in either group.

conclusionsThese results indicate that physical symptom management should be a crucial target of psychological intervention for returning veterans with PTSD symptoms and deployment-related injuries.

Indexed as

AdultFemaleHumansLongitudinal StudiesMalePainStress Disorders, Post-TraumaticVeteransVeterans HealthInjuryMutual MaintenancePain InterferencePosttraumatic Stress DisorderVeterans

Identifiers

PMID30016463
PMCPMC6497092
OpenAlexW2884714410

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.