Evidence map›Paper›PMID 30016450›Full record

Trial reportInternational health2018

Comparative effects of three methods of promoting breastfeeding among human immunodeficiency virus-infected women in Uganda: a parallel randomized clinical trial.

Joyce Namale-Matovu, Arthur H Owora, Carol Onyango-Makumbi, Mike Mubiru, Prossy E Namuli, Mahnaz Motevalli-Oliner, Philippa Musoke, Monica Nolan, Mary G Fowler

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in International health, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Joyce Namale-MatovuMakerere University-Johns Hopkins University Research Collaboration, Upper Mulago Hill Road, Kampala, Uganda.
Arthur H OworaMakerere University-Johns Hopkins University Research Collaboration, Upper Mulago Hill Road, Kampala, Uganda.
Carol Onyango-MakumbiMakerere University-Johns Hopkins University Research Collaboration, Upper Mulago Hill Road, Kampala, Uganda.
Mike MubiruMakerere University-Johns Hopkins University Research Collaboration, Upper Mulago Hill Road, Kampala, Uganda.
Prossy E NamuliMakerere University-Johns Hopkins University Research Collaboration, Upper Mulago Hill Road, Kampala, Uganda.
Mahnaz Motevalli-OlinerMakerere University-Johns Hopkins University Research Collaboration, Upper Mulago Hill Road, Kampala, Uganda.
Philippa MusokeMakerere University-Johns Hopkins University Research Collaboration, Upper Mulago Hill Road, Kampala, Uganda.
Monica NolanMakerere University-Johns Hopkins University Research Collaboration, Upper Mulago Hill Road, Kampala, Uganda.
Mary G FowlerMakerere University-Johns Hopkins University Research Collaboration, Upper Mulago Hill Road, Kampala, Uganda.

Funding

The Johns Hopkins University - Uganda Clinical Trials UnitUM1AI069530 · NIAID · JOHNS HOPKINS UNIVERSITY · PI MARY Glenn Fowler, Philippa Musoke · 2012 to 2026
$34.8M
NIAID NIH HHS UM1 AI069530
6 · The paper itself

Abstract

Background: The objective of this study was to evaluate the comparative effects of three breastfeeding promotion interventions on the duration of exclusive breastfeeding (EBF) and any breastfeeding (BF) among human immunodeficiency virus (HIV)-infected women in Uganda. Methods: Between February 2012 and February 2013, 218 HIV-infected pregnant mothers were randomly assigned to (A) standard care (n=73), (B) enhanced family/peer support (n=72) or (C) enhanced nutrition education (n=73). Results: The prevalence (%) of EBF/BF did not differ between intervention arms at the sixth (A, 85/92; B, 84/91; C, 87/89) and ninth (A, 17/91; B, 18/89; C, 16/87) postpartum month assessments (p>0.05). However, the risk of early BF cessation differed between intervention arms depending on the mother's level of formal education (p=0.04). Among women with no formal education, the risk of early BF cessation was 88% (adjusted hazard ratio [aHR] 0.12 [95% confidence interval {CI} 0.05-0.30]) and 93% (aHR 0.07 [95% CI 0.03-0.18]) lower in arms B and C, respectively, than in arm A (p<0.01). HIV status disclosure to a partner was associated with a higher risk of early EBF (p=0.03) and BF (p=0.04) cessation. Conclusions: In resource-limited settings, enhanced (vs standard care) EBF promotion interventions may not differentially influence EBF but reduce the risk of early BF cessation among women with no formal education. Targeted enhanced interventions among women with no formal education and a mother's partner may be critical to reducing the risk of early EBF/BF cessation.

Indexed as

AdultBreast FeedingEducational StatusFemaleHealth BehaviorHealth EducationHIV InfectionsHumansMothersPrevalenceSocioeconomic FactorsUgandaYoung Adult

Identifiers

PMID30016450
PMCPMC6500425

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.