ArticleAlcohol and alcoholism (Oxford, Oxfordshire)2018
Identifying and Characterizing Subpopulations of Heavy Alcohol Drinkers Via a Sucrose Preference Test: A Sweet Road to a Better Phenotypic Characterization?
Article in Alcohol and alcoholism (Oxford, Oxfordshire), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.
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Who cites it
12 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Sweet-liking and sugar supplementation as innovative components in substance use disorder treatment: A systematic review.Journal of psychopharmacology (Oxford, England) · 2025Pooled it
- Comparing body composition between the sweet-liking phenotypes: experimental data, systematic review and individual participant data meta-analysis.International journal of obesity (2005) · 2024Pooled it
- Predicting alcohol consumption and reward sensitivity using responses for natural sucrose reward in non-food-restricted rats.Psychopharmacology · 2026Article
- Pharmacological Inhibition of HDAC6 Transiently Reduces Voluntary Ethanol Consumption in Male Mice.Alcohol, clinical & experimental research · 2026Article
- Firewater, fructose and appetite.Nature metabolism · 2025Article
- An exploratory analysis of the relationship between ultraprocessed food consumption, alcohol intake, body composition, and cardiometabolic markers in individuals with alcohol use disorder.Alcohol, clinical & experimental research · 2025Article
- Genomic and Behavioral Signatures of Selection for Ethanol Preference from the Heterogeneous Stock Collaborative Cross Mice - The Central Nucleus of the Amygdala.Addiction neuroscience · 2025Article
- Evaluating the association between alcohol sweetness preference, alcohol harm, and alcohol value.Experimental and clinical psychopharmacology · 2025Article
- Mouse parasubthalamicbioRxiv : the preprint server for biology · 2024Article
- Exploration of the Impact of Combining Risk Phenotypes on the Likelihood of Alcohol Problems in Young Adults.Alcohol and alcoholism (Oxford, Oxfordshire) · 2022Article
- Associations of Binge Drinking and Heavy Alcohol Use on Sugar and Fat Intake in a Cohort of Southern People Living with HIV.Alcohol and alcoholism (Oxford, Oxfordshire) · 2022Article
- Leptin Gene and Leptin Receptor Gene Polymorphisms in Alcohol Use Disorder: Findings Related to Psychopathology.Frontiers in psychiatry · 2021Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
aimsSweet preference in individuals with alcohol use disorder (AUD) has been associated with family history of AUD and personality traits. Therefore, testing sweet preference may help identify subpopulations of AUD individuals. SHORT SUMMARY: Sweet preference has been associated with family history of AUD and personality traits. We compared heavy drinkers based on their sweet liker status and using two cutoffs. Our findings support the role of sweet preference in heavy drinkers and point to the importance of how sweet likers are defined.
methodsThis study aimed at describing and comparing heavy drinkers based on their sweet liker status, through demographic, neuroendocrine, inflammatory, behavioral and drinking characteristics. Participants rated the pleasantness and intensity of sucrose solutions (0.05, 0.10, 0.21, 0.42 and 0.83 M). Two cutoffs were used to identify likers versus dislikers: Grouping A likers preferred 0.83 M and Grouping B likers preferred 0.83 or 0.42 M; the rest were dislikers.
resultsSweet likers were 36% (n = 20) using Grouping A and 58.2% (n = 32) using Grouping B. Grouping B, but not Grouping A, sweet likers had higher BMI (P = 0.01). In Grouping B, sweet likers had higher plasma leptin and insulin concentrations and higher insulin resistance (P's < 0.05). C-reactive protein concentrations were higher in sweet likers in Grouping A (P = 0.0015) and at a trend level in Grouping B (P = 0.07). Grouping A sweet likers had higher alcohol craving (P = 0.0004). Sweet likers preferred spirits compared to nonspirits (wine and beer) across both grouping (P's < 0.05).
conclusionsThese results provide further support for the role of sweet liking phenotype in identifying subpopulations of AUD individuals. These findings also point to the importance of how sweet likers are defined, therefore highlighting the need for further research.
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