Evidence map›Paper›PMID 30016256›Full record

ArticleEmerging infectious diseases2018

Case Definition of Chronic Pulmonary Aspergillosis in Resource-Constrained Settings.

David W Denning, Iain D Page, Jeremiah Chakaya, Kauser Jabeen, Cecilia M Jude, Muriel Cornet, Ana Alastruey-Izquierdo, Felix Bongomin, Paul Bowyer, Arunaloke Chakrabarti and 23 more

Open access · diamondAbstract read
In one paragraph

Article in Emerging infectious diseases, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 80 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
80citing papers in PubMed, 2 pooled it
8.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

80 citing papers in PubMed, 2 syntheses or guidelines pooled it, 140 citations in OpenAlex.

  1. A Systematic Review of Chronic Pulmonary Aspergillosis Among Patients Treated for Pulmonary Tuberculosis.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2025
    Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Performance of the LDBioMicrobiology spectrum · 2026
    Article
  6. Article
  7. Multiplex CRISPR/Cas9 editing of gliotoxin biosynthesis genes in Aspergillus fumigatus reduces pathogenicity in broilers.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2026
    Article
  8. Article
  9. Review
  10. Article
  11. Diagnostic performance ofJournal of thoracic disease · 2025
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Chronic pulmonary aspergillosis in tea population of Assam.PLoS neglected tropical diseases · 2025
    Article
  19. Molecular identification and antifungal susceptibility testing ofAfrican journal of laboratory medicine · 2025
    Article
  20. Article

20 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

33 authors.

David W Denning
Iain D Page
Jeremiah Chakaya
Kauser Jabeen
Cecilia M Jude
Muriel Cornet
Ana Alastruey-Izquierdo
Felix Bongomin
Paul Bowyer
Arunaloke Chakrabarti
Sara Gago
John Guto
Bruno Hochhegger
Martin Hoenigl
Muhammad Irfan
Nicholas Irurhe
Koichi Izumikawa
Bruce Kirenga
Veronica Manduku
Samihah Moazam
Rita O Oladele
Malcolm D Richardson
Juan Luis Rodriguez Tudela
Anna Rozaliyani
Helmut J F Salzer
Richard Sawyer
Nasilele F Simukulwa
Alena Skrahina
Charlotte Sriruttan
Findra Setianingrum
Bayu A P Wilopo
Donald C Cole
Haileyesus Getahun

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic pulmonary aspergillosis (CPA) is a recognized complication of pulmonary tuberculosis (TB). In 2015, the World Health Organization reported 2.2 million new cases of nonbacteriologically confirmed pulmonary TB; some of these patients probably had undiagnosed CPA. In October 2016, the Global Action Fund for Fungal Infections convened an international expert panel to develop a case definition of CPA for resource-constrained settings. This panel defined CPA as illness for >3 months and all of the following: 1) weight loss, persistent cough, and/or hemoptysis; 2) chest images showing progressive cavitary infiltrates and/or a fungal ball and/or pericavitary fibrosis or infiltrates or pleural thickening; and 3) a positive Aspergillus IgG assay result or other evidence of Aspergillus infection. The proposed definition will facilitate advancements in research, practice, and policy in lower- and middle-income countries as well as in resource-constrained settings.

Indexed as

Chronic DiseaseDeveloping CountriesHumansPractice Guidelines as TopicPulmonary AspergillosisSocioeconomic FactorsantibodyaspergillomaAspergillusdeveloping countriesfungiimagingresource-constrained settingsTuberculosistuberculosis and other mycobacteria

Identifiers

PMID30016256
PMCPMC6056117
OpenAlexW2810754029

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.