Evidence map›Paper›PMID 30016242›Full record

ArticleEmerging infectious diseases2018

Distinguishing Zika and Dengue Viruses through Simple Clinical Assessment, Singapore.

Gabriel Yan, Long Pang, Alex R Cook, Hanley J Ho, Mar Soe Win, Ai Leng Khoo, Joshua G X Wong, Chun Kiat Lee, Benedict Yan, Roland Jureen and 10 more

Abstract read
In one paragraph

Article in Emerging infectious diseases, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. SARS-CoV-2 and arbovirus infection: a rapid systematic review.Sao Paulo medical journal = Revista paulista de medicina
    Pooled it
  2. Zika Virus: A Tale of Two Lineages.Pathogens (Basel, Switzerland) · 2025
    Review
  3. Article
  4. Review
  5. Article
  6. Trends in ELISA-Based Flavivirus IgG Serosurveys: A Systematic Review.Tropical medicine and infectious disease · 2023
    Review
  7. Article
  8. Zika virus as an emerging arbovirus of international public health concern.Osong public health and research perspectives · 2022
    Article
  9. Article
  10. Thrombocytopenia in Virus Infections.Journal of clinical medicine · 2021
    Review
  11. Article
  12. Article
  13. Review
  14. Mucocutaneous Features of Zika-a Review.Current infectious disease reports · 2019
    Review
  15. Article
  16. Article
  17. Article
  18. Clinical and laboratory findings of acute Zika virus infection in patients from Salvador during the first Brazilian epidemic.The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Gabriel Yan
Long Pang
Alex R Cook
Hanley J Ho
Mar Soe Win
Ai Leng Khoo
Joshua G X Wong
Chun Kiat Lee
Benedict Yan
Roland Jureen
Siew Seen Ho
David C Lye
Paul A Tambyah
Yee Sin Leo
Dale Fisher
Jolene Oon
Natasha Bagdasarian
Angela Chow
Nares Smitasin
Louis Yi Ann Chai

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dengue virus and Zika virus coexist in tropical regions in Asia where healthcare resources are limited; differentiating the 2 viruses is challenging. We showed in a case-control discovery cohort, and replicated in a validation cohort, that the diagnostic indices of conjunctivitis, platelet count, and monocyte count reliably distinguished between these viruses.

Indexed as

AdultAedesAgedAnimalsCase-Control StudiesCohort StudiesConjunctivitis, ViralDengueDengue VirusDiagnosis, DifferentialFemaleFeverHumansLeukocyte CountMaleMiddle Agedconjunctivitisdengue virusplateletsSingaporeSoutheast AsiavirusesZika viruszoonoses

Identifiers

PMID30016242
PMCPMC6056111

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.