ArticleJournal of clinical oncology : official journal of the American Society of Clinical Oncology2018
Induction Chemotherapy Followed by Cetuximab Radiotherapy Is Not Superior to Concurrent Chemoradiotherapy for Head and Neck Carcinomas: Results of the GORTEC 2007-02 Phase III Randomized Trial.
5 registry-linked trialsAbstract read
In one paragraph
Article in Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 5 registered trials, which are not on this map. Cited by 60 papers, 4 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
60citing papers in PubMed, 4 pooled it
18.9field-weighted citation impact, top 1% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neoadjuvant Tislelizumab With Afatinib for the Treatment of Resectable Head and Neck Squamous Cell Carcinoma: A Single-Arm Phase 2 Trial (neoCHANCE-1 Trial)
A Prospective, Single-arm Clinical Study of Low-dose Radiotherapy Plus Tislelizumab in Combination With Afatinib for Neoadjuvant Treatment of Surgically Resectable Head and Neck Squamous Carcinoma
A Prospective, Single-arm Clinical Study of Immune-targeted Therapy Combined With Lysogenic HSV Virus for the Neoadjuvant Treatment of Surgically Resectable Head and Neck Squamous Carcinoma
Neoadjuvant Low-Dose Radiotherapy Plus Targeted Therapy and Immunotherapy vs. Targeted Therapy Plus Immunotherapy in Resectable Head and Neck Squamous Cell Carcinoma: A Prospective Randomized Controlled Trial
A Prospective Randomized Controlled Trial Comparing Low-Dose Radiotherapy Combined With Targeted Therapy and Immunotherapy Versus Targeted Therapy and Immunotherapy Alone as Neoadjuvant Therapy in Patients With Operable Head and Neck Squamous Cell Carcinoma.
Who cites it
60 citing papers in PubMed, 4 syntheses or guidelines pooled it, 147 citations in OpenAlex.
- Progress in immunotherapy for resectable head and neck squamous cell carcinoma.Medical oncology (Northwood, London, England) · 2025Pooled it
- Correlation Between Early Time-to-Event Outcomes and Overall Survival in Patients With Locally Advanced Head and Neck Squamous Cell Carcinoma Receiving Definitive Chemoradiation Therapy: Systematic Review and Meta-Analysis.Frontiers in oncology · 2022Pooled it
- Radiotherapy and Receptor Tyrosine Kinase Inhibition for Solid Cancers (ROCKIT): A Meta-Analysis of 13 Studies.JNCI cancer spectrum · 2021Pooled it
- Meta-analysis of chemotherapy in head and neck cancer (MACH-NC): An update on 107 randomized trials and 19,805 patients, on behalf of MACH-NC Group.Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology · 2021Pooled it
- nab-Paclitaxel and cisplatin followed by cisplatin and radiation (Arm 1) and nab-paclitaxel followed by cetuximab and radiation (Arm 2) for locally advanced head and neck squamous-cell carcinoma: a multicenter, non-randomized phase 2 trial.Medical oncology (Northwood, London, England) · 2021Trial
- Survival outcomes of the patients with advanced laryngeal squamous cell carcinoma treated with chemoradiotherapy and total laryngectomy based on reports of head and neck cancer registry of Japan.International journal of clinical oncology · 2026Article
- Review
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- PD-1 inhibitors combined with induction chemotherapy followed by chemoradiotherapy in HPV-negative locally advanced head and neck squamous cell carcinoma: a real-world study.Cancer immunology, immunotherapy : CII · 2026Article
- Retrospective analysis of nanoparticle albumin-bound paclitaxel combined with toripalimab and platinum as first-line treatment for Chinese patients with recurrent or metastatic head and neck cancer.Frontiers in oncology · 2026Article
- Prognostic significance of dipeptidyl peptidase-7 (DPP7) in HPV16-negative head and neck squamous cell carcinoma treated with induction chemoradiotherapy.Discover oncology · 2025Article
- A systematic review and network meta-analysis of therapies for locally advanced head and neck squamous cell carcinoma with different HPV status.Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale · 2025Review
- Chemotherapy/Radiotherapy-Induced Dysphagia in Head and Neck Tumors: A Challenge for Otolaryngologists in Low- to Middle-Income Countries.Dysphagia · 2025Review
- Exploring the Therapeutic Implications of Co-Targeting the EGFR and Spindle Assembly Checkpoint Pathways in Oral Cancer.Pharmaceutics · 2024Review
- Advances and residual knowledge gaps in the neck management of head and neck squamous cell carcinoma patients with advanced nodal disease undergoing definitive (chemo)radiotherapy for their primary.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2024Review
- Serum Pro-Inflammatory Cytokines and Leptin as Potential Biomarkers for Treatment Response and Toxicity in Locally Advanced Squamous Cell Carcinoma of the Head and Neck.Diseases (Basel, Switzerland) · 2024Article
- Retrospective study of cisplatin plus radiotherapy toxicities in locally advanced squamous cell carcinoma of the head and neck - ReCisTT study.Frontiers in oncology · 2024Article
- Review
- Review
- Efficacy and feasibility of Apatinib and S-1 as a novel oral induction therapy in locally advanced head and neck squamous cell carcinoma: an exploratory phase 2 open-label, single-arm trial.Frontiers in oncology · 2023Article
Corrections and comments
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Authors and funding
32 authors at 1 institution in 1 country.
Lionnel GeoffroisLionnel Geoffrois, Marie-Christine Kaminsky, Institut de Cancérologie de Lorraine, Vandoeuvre Lès Nancy; Laurent Martin, Centre Guillaume le Conquérant; Dominique De Raucourt, Bernard Gery, Centre François Baclesse; Emmanuel Babin, Hopital Universitaire, Caen; Xu Shan Sun, Joëlle Buffet, Centre Hospitalier Universitaire de Besançon, Besançon; Hôpital de Mulhouse, Mulhouse; Yungan Tao, Gustave-Roussy Institute, Villejuif; Philippe Maingon, Centre François Leclercq, Leclercq; Yoann Pointreau, Cédric Lafond, Marie-Hélène Calais, Pascal Garaud, Centre Jean Bernard, Le Mans; Centre Hospitalier Universitaire de Tours, Tours; Christian Sire, Centre Hospitalier de Lorient, Lorient; Claude Tuchais, Eric Jadaud, Centre Paul Papin, Angers; Alexandre Coutte, Centre Hospitalier Universitaire Amiens, Amiens; Frédéric Rolland, Centre René Gauducheau, Saint Herblain; Marc Alfonsi, Clinique Sainte Catherine, Avignon; Michel Lapeyre, Centre Jean Perrin, Clermont; Marie Saliou, Clinique Mutualiste, Saint Nazaire; Ayman Zawadi, Centre Hospitalier de La Roche-sur-Yon, La Roche-sur-Yon; Jean-Marc Tourani, Centre Hospitalier Universitaire, Poitiers, Poitiers; Cédric Khoury, Centre Saint Louis; Pierre Guillet, Hôpital Font-Pré, Toulon, Toulon; Ali Hasbini, Hopital de Saint Brieuc, Saint Brieuc; François Guichard, Polyclinique de Bordeaux-Nord, Bordeaux; Christian Borel, Centre Paul Strauss, Strasbourg, France; Anne Rose Henry, Hôpital Montigny le Tilleul, Montigny-le-Tilleul; Nicolas Meert, Centre Hospitalier de Charlebois, Charlebois, Belgium; and Jean Bourhis, Centre Hospitalier Universitaire Vaudois Lausanne, Lausanne, Switzerland.
Laurent MartinLionnel Geoffrois, Marie-Christine Kaminsky, Institut de Cancérologie de Lorraine, Vandoeuvre Lès Nancy; Laurent Martin, Centre Guillaume le Conquérant; Dominique De Raucourt, Bernard Gery, Centre François Baclesse; Emmanuel Babin, Hopital Universitaire, Caen; Xu Shan Sun, Joëlle Buffet, Centre Hospitalier Universitaire de Besançon, Besançon; Hôpital de Mulhouse, Mulhouse; Yungan Tao, Gustave-Roussy Institute, Villejuif; Philippe Maingon, Centre François Leclercq, Leclercq; Yoann Pointreau, Cédric Lafond, Marie-Hélène Calais, Pascal Garaud, Centre Jean Bernard, Le Mans; Centre Hospitalier Universitaire de Tours, Tours; Christian Sire, Centre Hospitalier de Lorient, Lorient; Claude Tuchais, Eric Jadaud, Centre Paul Papin, Angers; Alexandre Coutte, Centre Hospitalier Universitaire Amiens, Amiens; Frédéric Rolland, Centre René Gauducheau, Saint Herblain; Marc Alfonsi, Clinique Sainte Catherine, Avignon; Michel Lapeyre, Centre Jean Perrin, Clermont; Marie Saliou, Clinique Mutualiste, Saint Nazaire; Ayman Zawadi, Centre Hospitalier de La Roche-sur-Yon, La Roche-sur-Yon; Jean-Marc Tourani, Centre Hospitalier Universitaire, Poitiers, Poitiers; Cédric Khoury, Centre Saint Louis; Pierre Guillet, Hôpital Font-Pré, Toulon, Toulon; Ali Hasbini, Hopital de Saint Brieuc, Saint Brieuc; François Guichard, Polyclinique de Bordeaux-Nord, Bordeaux; Christian Borel, Centre Paul Strauss, Strasbourg, France; Anne Rose Henry, Hôpital Montigny le Tilleul, Montigny-le-Tilleul; Nicolas Meert, Centre Hospitalier de Charlebois, Charlebois, Belgium; and Jean Bourhis, Centre Hospitalier Universitaire Vaudois Lausanne, Lausanne, Switzerland.
Dominique De RaucourtLionnel Geoffrois, Marie-Christine Kaminsky, Institut de Cancérologie de Lorraine, Vandoeuvre Lès Nancy; Laurent Martin, Centre Guillaume le Conquérant; Dominique De Raucourt, Bernard Gery, Centre François Baclesse; Emmanuel Babin, Hopital Universitaire, Caen; Xu Shan Sun, Joëlle Buffet, Centre Hospitalier Universitaire de Besançon, Besançon; Hôpital de Mulhouse, Mulhouse; Yungan Tao, Gustave-Roussy Institute, Villejuif; Philippe Maingon, Centre François Leclercq, Leclercq; Yoann Pointreau, Cédric Lafond, Marie-Hélène Calais, Pascal Garaud, Centre Jean Bernard, Le Mans; Centre Hospitalier Universitaire de Tours, Tours; Christian Sire, Centre Hospitalier de Lorient, Lorient; Claude Tuchais, Eric Jadaud, Centre Paul Papin, Angers; Alexandre Coutte, Centre Hospitalier Universitaire Amiens, Amiens; Frédéric Rolland, Centre René Gauducheau, Saint Herblain; Marc Alfonsi, Clinique Sainte Catherine, Avignon; Michel Lapeyre, Centre Jean Perrin, Clermont; Marie Saliou, Clinique Mutualiste, Saint Nazaire; Ayman Zawadi, Centre Hospitalier de La Roche-sur-Yon, La Roche-sur-Yon; Jean-Marc Tourani, Centre Hospitalier Universitaire, Poitiers, Poitiers; Cédric Khoury, Centre Saint Louis; Pierre Guillet, Hôpital Font-Pré, Toulon, Toulon; Ali Hasbini, Hopital de Saint Brieuc, Saint Brieuc; François Guichard, Polyclinique de Bordeaux-Nord, Bordeaux; Christian Borel, Centre Paul Strauss, Strasbourg, France; Anne Rose Henry, Hôpital Montigny le Tilleul, Montigny-le-Tilleul; Nicolas Meert, Centre Hospitalier de Charlebois, Charlebois, Belgium; and Jean Bourhis, Centre Hospitalier Universitaire Vaudois Lausanne, Lausanne, Switzerland.
Xu Shan SunLionnel Geoffrois, Marie-Christine Kaminsky, Institut de Cancérologie de Lorraine, Vandoeuvre Lès Nancy; Laurent Martin, Centre Guillaume le Conquérant; Dominique De Raucourt, Bernard Gery, Centre François Baclesse; Emmanuel Babin, Hopital Universitaire, Caen; Xu Shan Sun, Joëlle Buffet, Centre Hospitalier Universitaire de Besançon, Besançon; Hôpital de Mulhouse, Mulhouse; Yungan Tao, Gustave-Roussy Institute, Villejuif; Philippe Maingon, Centre François Leclercq, Leclercq; Yoann Pointreau, Cédric Lafond, Marie-Hélène Calais, Pascal Garaud, Centre Jean Bernard, Le Mans; Centre Hospitalier Universitaire de Tours, Tours; Christian Sire, Centre Hospitalier de Lorient, Lorient; Claude Tuchais, Eric Jadaud, Centre Paul Papin, Angers; Alexandre Coutte, Centre Hospitalier Universitaire Amiens, Amiens; Frédéric Rolland, Centre René Gauducheau, Saint Herblain; Marc Alfonsi, Clinique Sainte Catherine, Avignon; Michel Lapeyre, Centre Jean Perrin, Clermont; Marie Saliou, Clinique Mutualiste, Saint Nazaire; Ayman Zawadi, Centre Hospitalier de La Roche-sur-Yon, La Roche-sur-Yon; Jean-Marc Tourani, Centre Hospitalier Universitaire, Poitiers, Poitiers; Cédric Khoury, Centre Saint Louis; Pierre Guillet, Hôpital Font-Pré, Toulon, Toulon; Ali Hasbini, Hopital de Saint Brieuc, Saint Brieuc; François Guichard, Polyclinique de Bordeaux-Nord, Bordeaux; Christian Borel, Centre Paul Strauss, Strasbourg, France; Anne Rose Henry, Hôpital Montigny le Tilleul, Montigny-le-Tilleul; Nicolas Meert, Centre Hospitalier de Charlebois, Charlebois, Belgium; and Jean Bourhis, Centre Hospitalier Universitaire Vaudois Lausanne, Lausanne, Switzerland.
Yungan TaoLionnel Geoffrois, Marie-Christine Kaminsky, Institut de Cancérologie de Lorraine, Vandoeuvre Lès Nancy; Laurent Martin, Centre Guillaume le Conquérant; Dominique De Raucourt, Bernard Gery, Centre François Baclesse; Emmanuel Babin, Hopital Universitaire, Caen; Xu Shan Sun, Joëlle Buffet, Centre Hospitalier Universitaire de Besançon, Besançon; Hôpital de Mulhouse, Mulhouse; Yungan Tao, Gustave-Roussy Institute, Villejuif; Philippe Maingon, Centre François Leclercq, Leclercq; Yoann Pointreau, Cédric Lafond, Marie-Hélène Calais, Pascal Garaud, Centre Jean Bernard, Le Mans; Centre Hospitalier Universitaire de Tours, Tours; Christian Sire, Centre Hospitalier de Lorient, Lorient; Claude Tuchais, Eric Jadaud, Centre Paul Papin, Angers; Alexandre Coutte, Centre Hospitalier Universitaire Amiens, Amiens; Frédéric Rolland, Centre René Gauducheau, Saint Herblain; Marc Alfonsi, Clinique Sainte Catherine, Avignon; Michel Lapeyre, Centre Jean Perrin, Clermont; Marie Saliou, Clinique Mutualiste, Saint Nazaire; Ayman Zawadi, Centre Hospitalier de La Roche-sur-Yon, La Roche-sur-Yon; Jean-Marc Tourani, Centre Hospitalier Universitaire, Poitiers, Poitiers; Cédric Khoury, Centre Saint Louis; Pierre Guillet, Hôpital Font-Pré, Toulon, Toulon; Ali Hasbini, Hopital de Saint Brieuc, Saint Brieuc; François Guichard, Polyclinique de Bordeaux-Nord, Bordeaux; Christian Borel, Centre Paul Strauss, Strasbourg, France; Anne Rose Henry, Hôpital Montigny le Tilleul, Montigny-le-Tilleul; Nicolas Meert, Centre Hospitalier de Charlebois, Charlebois, Belgium; and Jean Bourhis, Centre Hospitalier Universitaire Vaudois Lausanne, Lausanne, Switzerland.
Philippe MaingonLionnel Geoffrois, Marie-Christine Kaminsky, Institut de Cancérologie de Lorraine, Vandoeuvre Lès Nancy; Laurent Martin, Centre Guillaume le Conquérant; Dominique De Raucourt, Bernard Gery, Centre François Baclesse; Emmanuel Babin, Hopital Universitaire, Caen; Xu Shan Sun, Joëlle Buffet, Centre Hospitalier Universitaire de Besançon, Besançon; Hôpital de Mulhouse, Mulhouse; Yungan Tao, Gustave-Roussy Institute, Villejuif; Philippe Maingon, Centre François Leclercq, Leclercq; Yoann Pointreau, Cédric Lafond, Marie-Hélène Calais, Pascal Garaud, Centre Jean Bernard, Le Mans; Centre Hospitalier Universitaire de Tours, Tours; Christian Sire, Centre Hospitalier de Lorient, Lorient; Claude Tuchais, Eric Jadaud, Centre Paul Papin, Angers; Alexandre Coutte, Centre Hospitalier Universitaire Amiens, Amiens; Frédéric Rolland, Centre René Gauducheau, Saint Herblain; Marc Alfonsi, Clinique Sainte Catherine, Avignon; Michel Lapeyre, Centre Jean Perrin, Clermont; Marie Saliou, Clinique Mutualiste, Saint Nazaire; Ayman Zawadi, Centre Hospitalier de La Roche-sur-Yon, La Roche-sur-Yon; Jean-Marc Tourani, Centre Hospitalier Universitaire, Poitiers, Poitiers; Cédric Khoury, Centre Saint Louis; Pierre Guillet, Hôpital Font-Pré, Toulon, Toulon; Ali Hasbini, Hopital de Saint Brieuc, Saint Brieuc; François Guichard, Polyclinique de Bordeaux-Nord, Bordeaux; Christian Borel, Centre Paul Strauss, Strasbourg, France; Anne Rose Henry, Hôpital Montigny le Tilleul, Montigny-le-Tilleul; Nicolas Meert, Centre Hospitalier de Charlebois, Charlebois, Belgium; and Jean Bourhis, Centre Hospitalier Universitaire Vaudois Lausanne, Lausanne, Switzerland.
Joëlle BuffetLionnel Geoffrois, Marie-Christine Kaminsky, Institut de Cancérologie de Lorraine, Vandoeuvre Lès Nancy; Laurent Martin, Centre Guillaume le Conquérant; Dominique De Raucourt, Bernard Gery, Centre François Baclesse; Emmanuel Babin, Hopital Universitaire, Caen; Xu Shan Sun, Joëlle Buffet, Centre Hospitalier Universitaire de Besançon, Besançon; Hôpital de Mulhouse, Mulhouse; Yungan Tao, Gustave-Roussy Institute, Villejuif; Philippe Maingon, Centre François Leclercq, Leclercq; Yoann Pointreau, Cédric Lafond, Marie-Hélène Calais, Pascal Garaud, Centre Jean Bernard, Le Mans; Centre Hospitalier Universitaire de Tours, Tours; Christian Sire, Centre Hospitalier de Lorient, Lorient; Claude Tuchais, Eric Jadaud, Centre Paul Papin, Angers; Alexandre Coutte, Centre Hospitalier Universitaire Amiens, Amiens; Frédéric Rolland, Centre René Gauducheau, Saint Herblain; Marc Alfonsi, Clinique Sainte Catherine, Avignon; Michel Lapeyre, Centre Jean Perrin, Clermont; Marie Saliou, Clinique Mutualiste, Saint Nazaire; Ayman Zawadi, Centre Hospitalier de La Roche-sur-Yon, La Roche-sur-Yon; Jean-Marc Tourani, Centre Hospitalier Universitaire, Poitiers, Poitiers; Cédric Khoury, Centre Saint Louis; Pierre Guillet, Hôpital Font-Pré, Toulon, Toulon; Ali Hasbini, Hopital de Saint Brieuc, Saint Brieuc; François Guichard, Polyclinique de Bordeaux-Nord, Bordeaux; Christian Borel, Centre Paul Strauss, Strasbourg, France; Anne Rose Henry, Hôpital Montigny le Tilleul, Montigny-le-Tilleul; Nicolas Meert, Centre Hospitalier de Charlebois, Charlebois, Belgium; and Jean Bourhis, Centre Hospitalier Universitaire Vaudois Lausanne, Lausanne, Switzerland.
Yoann PointreauLionnel Geoffrois, Marie-Christine Kaminsky, Institut de Cancérologie de Lorraine, Vandoeuvre Lès Nancy; Laurent Martin, Centre Guillaume le Conquérant; Dominique De Raucourt, Bernard Gery, Centre François Baclesse; Emmanuel Babin, Hopital Universitaire, Caen; Xu Shan Sun, Joëlle Buffet, Centre Hospitalier Universitaire de Besançon, Besançon; Hôpital de Mulhouse, Mulhouse; Yungan Tao, Gustave-Roussy Institute, Villejuif; Philippe Maingon, Centre François Leclercq, Leclercq; Yoann Pointreau, Cédric Lafond, Marie-Hélène Calais, Pascal Garaud, Centre Jean Bernard, Le Mans; Centre Hospitalier Universitaire de Tours, Tours; Christian Sire, Centre Hospitalier de Lorient, Lorient; Claude Tuchais, Eric Jadaud, Centre Paul Papin, Angers; Alexandre Coutte, Centre Hospitalier Universitaire Amiens, Amiens; Frédéric Rolland, Centre René Gauducheau, Saint Herblain; Marc Alfonsi, Clinique Sainte Catherine, Avignon; Michel Lapeyre, Centre Jean Perrin, Clermont; Marie Saliou, Clinique Mutualiste, Saint Nazaire; Ayman Zawadi, Centre Hospitalier de La Roche-sur-Yon, La Roche-sur-Yon; Jean-Marc Tourani, Centre Hospitalier Universitaire, Poitiers, Poitiers; Cédric Khoury, Centre Saint Louis; Pierre Guillet, Hôpital Font-Pré, Toulon, Toulon; Ali Hasbini, Hopital de Saint Brieuc, Saint Brieuc; François Guichard, Polyclinique de Bordeaux-Nord, Bordeaux; Christian Borel, Centre Paul Strauss, Strasbourg, France; Anne Rose Henry, Hôpital Montigny le Tilleul, Montigny-le-Tilleul; Nicolas Meert, Centre Hospitalier de Charlebois, Charlebois, Belgium; and Jean Bourhis, Centre Hospitalier Universitaire Vaudois Lausanne, Lausanne, Switzerland.
Christian SireLionnel Geoffrois, Marie-Christine Kaminsky, Institut de Cancérologie de Lorraine, Vandoeuvre Lès Nancy; Laurent Martin, Centre Guillaume le Conquérant; Dominique De Raucourt, Bernard Gery, Centre François Baclesse; Emmanuel Babin, Hopital Universitaire, Caen; Xu Shan Sun, Joëlle Buffet, Centre Hospitalier Universitaire de Besançon, Besançon; Hôpital de Mulhouse, Mulhouse; Yungan Tao, Gustave-Roussy Institute, Villejuif; Philippe Maingon, Centre François Leclercq, Leclercq; Yoann Pointreau, Cédric Lafond, Marie-Hélène Calais, Pascal Garaud, Centre Jean Bernard, Le Mans; Centre Hospitalier Universitaire de Tours, Tours; Christian Sire, Centre Hospitalier de Lorient, Lorient; Claude Tuchais, Eric Jadaud, Centre Paul Papin, Angers; Alexandre Coutte, Centre Hospitalier Universitaire Amiens, Amiens; Frédéric Rolland, Centre René Gauducheau, Saint Herblain; Marc Alfonsi, Clinique Sainte Catherine, Avignon; Michel Lapeyre, Centre Jean Perrin, Clermont; Marie Saliou, Clinique Mutualiste, Saint Nazaire; Ayman Zawadi, Centre Hospitalier de La Roche-sur-Yon, La Roche-sur-Yon; Jean-Marc Tourani, Centre Hospitalier Universitaire, Poitiers, Poitiers; Cédric Khoury, Centre Saint Louis; Pierre Guillet, Hôpital Font-Pré, Toulon, Toulon; Ali Hasbini, Hopital de Saint Brieuc, Saint Brieuc; François Guichard, Polyclinique de Bordeaux-Nord, Bordeaux; Christian Borel, Centre Paul Strauss, Strasbourg, France; Anne Rose Henry, Hôpital Montigny le Tilleul, Montigny-le-Tilleul; Nicolas Meert, Centre Hospitalier de Charlebois, Charlebois, Belgium; and Jean Bourhis, Centre Hospitalier Universitaire Vaudois Lausanne, Lausanne, Switzerland.
Claude TuchaisLionnel Geoffrois, Marie-Christine Kaminsky, Institut de Cancérologie de Lorraine, Vandoeuvre Lès Nancy; Laurent Martin, Centre Guillaume le Conquérant; Dominique De Raucourt, Bernard Gery, Centre François Baclesse; Emmanuel Babin, Hopital Universitaire, Caen; Xu Shan Sun, Joëlle Buffet, Centre Hospitalier Universitaire de Besançon, Besançon; Hôpital de Mulhouse, Mulhouse; Yungan Tao, Gustave-Roussy Institute, Villejuif; Philippe Maingon, Centre François Leclercq, Leclercq; Yoann Pointreau, Cédric Lafond, Marie-Hélène Calais, Pascal Garaud, Centre Jean Bernard, Le Mans; Centre Hospitalier Universitaire de Tours, Tours; Christian Sire, Centre Hospitalier de Lorient, Lorient; Claude Tuchais, Eric Jadaud, Centre Paul Papin, Angers; Alexandre Coutte, Centre Hospitalier Universitaire Amiens, Amiens; Frédéric Rolland, Centre René Gauducheau, Saint Herblain; Marc Alfonsi, Clinique Sainte Catherine, Avignon; Michel Lapeyre, Centre Jean Perrin, Clermont; Marie Saliou, Clinique Mutualiste, Saint Nazaire; Ayman Zawadi, Centre Hospitalier de La Roche-sur-Yon, La Roche-sur-Yon; Jean-Marc Tourani, Centre Hospitalier Universitaire, Poitiers, Poitiers; Cédric Khoury, Centre Saint Louis; Pierre Guillet, Hôpital Font-Pré, Toulon, Toulon; Ali Hasbini, Hopital de Saint Brieuc, Saint Brieuc; François Guichard, Polyclinique de Bordeaux-Nord, Bordeaux; Christian Borel, Centre Paul Strauss, Strasbourg, France; Anne Rose Henry, Hôpital Montigny le Tilleul, Montigny-le-Tilleul; Nicolas Meert, Centre Hospitalier de Charlebois, Charlebois, Belgium; and Jean Bourhis, Centre Hospitalier Universitaire Vaudois Lausanne, Lausanne, Switzerland.
Emmanuel BabinLionnel Geoffrois, Marie-Christine Kaminsky, Institut de Cancérologie de Lorraine, Vandoeuvre Lès Nancy; Laurent Martin, Centre Guillaume le Conquérant; Dominique De Raucourt, Bernard Gery, Centre François Baclesse; Emmanuel Babin, Hopital Universitaire, Caen; Xu Shan Sun, Joëlle Buffet, Centre Hospitalier Universitaire de Besançon, Besançon; Hôpital de Mulhouse, Mulhouse; Yungan Tao, Gustave-Roussy Institute, Villejuif; Philippe Maingon, Centre François Leclercq, Leclercq; Yoann Pointreau, Cédric Lafond, Marie-Hélène Calais, Pascal Garaud, Centre Jean Bernard, Le Mans; Centre Hospitalier Universitaire de Tours, Tours; Christian Sire, Centre Hospitalier de Lorient, Lorient; Claude Tuchais, Eric Jadaud, Centre Paul Papin, Angers; Alexandre Coutte, Centre Hospitalier Universitaire Amiens, Amiens; Frédéric Rolland, Centre René Gauducheau, Saint Herblain; Marc Alfonsi, Clinique Sainte Catherine, Avignon; Michel Lapeyre, Centre Jean Perrin, Clermont; Marie Saliou, Clinique Mutualiste, Saint Nazaire; Ayman Zawadi, Centre Hospitalier de La Roche-sur-Yon, La Roche-sur-Yon; Jean-Marc Tourani, Centre Hospitalier Universitaire, Poitiers, Poitiers; Cédric Khoury, Centre Saint Louis; Pierre Guillet, Hôpital Font-Pré, Toulon, Toulon; Ali Hasbini, Hopital de Saint Brieuc, Saint Brieuc; François Guichard, Polyclinique de Bordeaux-Nord, Bordeaux; Christian Borel, Centre Paul Strauss, Strasbourg, France; Anne Rose Henry, Hôpital Montigny le Tilleul, Montigny-le-Tilleul; Nicolas Meert, Centre Hospitalier de Charlebois, Charlebois, Belgium; and Jean Bourhis, Centre Hospitalier Universitaire Vaudois Lausanne, Lausanne, Switzerland.
Alexandre CoutteLionnel Geoffrois, Marie-Christine Kaminsky, Institut de Cancérologie de Lorraine, Vandoeuvre Lès Nancy; Laurent Martin, Centre Guillaume le Conquérant; Dominique De Raucourt, Bernard Gery, Centre François Baclesse; Emmanuel Babin, Hopital Universitaire, Caen; Xu Shan Sun, Joëlle Buffet, Centre Hospitalier Universitaire de Besançon, Besançon; Hôpital de Mulhouse, Mulhouse; Yungan Tao, Gustave-Roussy Institute, Villejuif; Philippe Maingon, Centre François Leclercq, Leclercq; Yoann Pointreau, Cédric Lafond, Marie-Hélène Calais, Pascal Garaud, Centre Jean Bernard, Le Mans; Centre Hospitalier Universitaire de Tours, Tours; Christian Sire, Centre Hospitalier de Lorient, Lorient; Claude Tuchais, Eric Jadaud, Centre Paul Papin, Angers; Alexandre Coutte, Centre Hospitalier Universitaire Amiens, Amiens; Frédéric Rolland, Centre René Gauducheau, Saint Herblain; Marc Alfonsi, Clinique Sainte Catherine, Avignon; Michel Lapeyre, Centre Jean Perrin, Clermont; Marie Saliou, Clinique Mutualiste, Saint Nazaire; Ayman Zawadi, Centre Hospitalier de La Roche-sur-Yon, La Roche-sur-Yon; Jean-Marc Tourani, Centre Hospitalier Universitaire, Poitiers, Poitiers; Cédric Khoury, Centre Saint Louis; Pierre Guillet, Hôpital Font-Pré, Toulon, Toulon; Ali Hasbini, Hopital de Saint Brieuc, Saint Brieuc; François Guichard, Polyclinique de Bordeaux-Nord, Bordeaux; Christian Borel, Centre Paul Strauss, Strasbourg, France; Anne Rose Henry, Hôpital Montigny le Tilleul, Montigny-le-Tilleul; Nicolas Meert, Centre Hospitalier de Charlebois, Charlebois, Belgium; and Jean Bourhis, Centre Hospitalier Universitaire Vaudois Lausanne, Lausanne, Switzerland.
Frédéric RollandLionnel Geoffrois, Marie-Christine Kaminsky, Institut de Cancérologie de Lorraine, Vandoeuvre Lès Nancy; Laurent Martin, Centre Guillaume le Conquérant; Dominique De Raucourt, Bernard Gery, Centre François Baclesse; Emmanuel Babin, Hopital Universitaire, Caen; Xu Shan Sun, Joëlle Buffet, Centre Hospitalier Universitaire de Besançon, Besançon; Hôpital de Mulhouse, Mulhouse; Yungan Tao, Gustave-Roussy Institute, Villejuif; Philippe Maingon, Centre François Leclercq, Leclercq; Yoann Pointreau, Cédric Lafond, Marie-Hélène Calais, Pascal Garaud, Centre Jean Bernard, Le Mans; Centre Hospitalier Universitaire de Tours, Tours; Christian Sire, Centre Hospitalier de Lorient, Lorient; Claude Tuchais, Eric Jadaud, Centre Paul Papin, Angers; Alexandre Coutte, Centre Hospitalier Universitaire Amiens, Amiens; Frédéric Rolland, Centre René Gauducheau, Saint Herblain; Marc Alfonsi, Clinique Sainte Catherine, Avignon; Michel Lapeyre, Centre Jean Perrin, Clermont; Marie Saliou, Clinique Mutualiste, Saint Nazaire; Ayman Zawadi, Centre Hospitalier de La Roche-sur-Yon, La Roche-sur-Yon; Jean-Marc Tourani, Centre Hospitalier Universitaire, Poitiers, Poitiers; Cédric Khoury, Centre Saint Louis; Pierre Guillet, Hôpital Font-Pré, Toulon, Toulon; Ali Hasbini, Hopital de Saint Brieuc, Saint Brieuc; François Guichard, Polyclinique de Bordeaux-Nord, Bordeaux; Christian Borel, Centre Paul Strauss, Strasbourg, France; Anne Rose Henry, Hôpital Montigny le Tilleul, Montigny-le-Tilleul; Nicolas Meert, Centre Hospitalier de Charlebois, Charlebois, Belgium; and Jean Bourhis, Centre Hospitalier Universitaire Vaudois Lausanne, Lausanne, Switzerland.
Marie-Christine KaminskyLionnel Geoffrois, Marie-Christine Kaminsky, Institut de Cancérologie de Lorraine, Vandoeuvre Lès Nancy; Laurent Martin, Centre Guillaume le Conquérant; Dominique De Raucourt, Bernard Gery, Centre François Baclesse; Emmanuel Babin, Hopital Universitaire, Caen; Xu Shan Sun, Joëlle Buffet, Centre Hospitalier Universitaire de Besançon, Besançon; Hôpital de Mulhouse, Mulhouse; Yungan Tao, Gustave-Roussy Institute, Villejuif; Philippe Maingon, Centre François Leclercq, Leclercq; Yoann Pointreau, Cédric Lafond, Marie-Hélène Calais, Pascal Garaud, Centre Jean Bernard, Le Mans; Centre Hospitalier Universitaire de Tours, Tours; Christian Sire, Centre Hospitalier de Lorient, Lorient; Claude Tuchais, Eric Jadaud, Centre Paul Papin, Angers; Alexandre Coutte, Centre Hospitalier Universitaire Amiens, Amiens; Frédéric Rolland, Centre René Gauducheau, Saint Herblain; Marc Alfonsi, Clinique Sainte Catherine, Avignon; Michel Lapeyre, Centre Jean Perrin, Clermont; Marie Saliou, Clinique Mutualiste, Saint Nazaire; Ayman Zawadi, Centre Hospitalier de La Roche-sur-Yon, La Roche-sur-Yon; Jean-Marc Tourani, Centre Hospitalier Universitaire, Poitiers, Poitiers; Cédric Khoury, Centre Saint Louis; Pierre Guillet, Hôpital Font-Pré, Toulon, Toulon; Ali Hasbini, Hopital de Saint Brieuc, Saint Brieuc; François Guichard, Polyclinique de Bordeaux-Nord, Bordeaux; Christian Borel, Centre Paul Strauss, Strasbourg, France; Anne Rose Henry, Hôpital Montigny le Tilleul, Montigny-le-Tilleul; Nicolas Meert, Centre Hospitalier de Charlebois, Charlebois, Belgium; and Jean Bourhis, Centre Hospitalier Universitaire Vaudois Lausanne, Lausanne, Switzerland.
Marc AlfonsiLionnel Geoffrois, Marie-Christine Kaminsky, Institut de Cancérologie de Lorraine, Vandoeuvre Lès Nancy; Laurent Martin, Centre Guillaume le Conquérant; Dominique De Raucourt, Bernard Gery, Centre François Baclesse; Emmanuel Babin, Hopital Universitaire, Caen; Xu Shan Sun, Joëlle Buffet, Centre Hospitalier Universitaire de Besançon, Besançon; Hôpital de Mulhouse, Mulhouse; Yungan Tao, Gustave-Roussy Institute, Villejuif; Philippe Maingon, Centre François Leclercq, Leclercq; Yoann Pointreau, Cédric Lafond, Marie-Hélène Calais, Pascal Garaud, Centre Jean Bernard, Le Mans; Centre Hospitalier Universitaire de Tours, Tours; Christian Sire, Centre Hospitalier de Lorient, Lorient; Claude Tuchais, Eric Jadaud, Centre Paul Papin, Angers; Alexandre Coutte, Centre Hospitalier Universitaire Amiens, Amiens; Frédéric Rolland, Centre René Gauducheau, Saint Herblain; Marc Alfonsi, Clinique Sainte Catherine, Avignon; Michel Lapeyre, Centre Jean Perrin, Clermont; Marie Saliou, Clinique Mutualiste, Saint Nazaire; Ayman Zawadi, Centre Hospitalier de La Roche-sur-Yon, La Roche-sur-Yon; Jean-Marc Tourani, Centre Hospitalier Universitaire, Poitiers, Poitiers; Cédric Khoury, Centre Saint Louis; Pierre Guillet, Hôpital Font-Pré, Toulon, Toulon; Ali Hasbini, Hopital de Saint Brieuc, Saint Brieuc; François Guichard, Polyclinique de Bordeaux-Nord, Bordeaux; Christian Borel, Centre Paul Strauss, Strasbourg, France; Anne Rose Henry, Hôpital Montigny le Tilleul, Montigny-le-Tilleul; Nicolas Meert, Centre Hospitalier de Charlebois, Charlebois, Belgium; and Jean Bourhis, Centre Hospitalier Universitaire Vaudois Lausanne, Lausanne, Switzerland.
Michel LapeyreLionnel Geoffrois, Marie-Christine Kaminsky, Institut de Cancérologie de Lorraine, Vandoeuvre Lès Nancy; Laurent Martin, Centre Guillaume le Conquérant; Dominique De Raucourt, Bernard Gery, Centre François Baclesse; Emmanuel Babin, Hopital Universitaire, Caen; Xu Shan Sun, Joëlle Buffet, Centre Hospitalier Universitaire de Besançon, Besançon; Hôpital de Mulhouse, Mulhouse; Yungan Tao, Gustave-Roussy Institute, Villejuif; Philippe Maingon, Centre François Leclercq, Leclercq; Yoann Pointreau, Cédric Lafond, Marie-Hélène Calais, Pascal Garaud, Centre Jean Bernard, Le Mans; Centre Hospitalier Universitaire de Tours, Tours; Christian Sire, Centre Hospitalier de Lorient, Lorient; Claude Tuchais, Eric Jadaud, Centre Paul Papin, Angers; Alexandre Coutte, Centre Hospitalier Universitaire Amiens, Amiens; Frédéric Rolland, Centre René Gauducheau, Saint Herblain; Marc Alfonsi, Clinique Sainte Catherine, Avignon; Michel Lapeyre, Centre Jean Perrin, Clermont; Marie Saliou, Clinique Mutualiste, Saint Nazaire; Ayman Zawadi, Centre Hospitalier de La Roche-sur-Yon, La Roche-sur-Yon; Jean-Marc Tourani, Centre Hospitalier Universitaire, Poitiers, Poitiers; Cédric Khoury, Centre Saint Louis; Pierre Guillet, Hôpital Font-Pré, Toulon, Toulon; Ali Hasbini, Hopital de Saint Brieuc, Saint Brieuc; François Guichard, Polyclinique de Bordeaux-Nord, Bordeaux; Christian Borel, Centre Paul Strauss, Strasbourg, France; Anne Rose Henry, Hôpital Montigny le Tilleul, Montigny-le-Tilleul; Nicolas Meert, Centre Hospitalier de Charlebois, Charlebois, Belgium; and Jean Bourhis, Centre Hospitalier Universitaire Vaudois Lausanne, Lausanne, Switzerland.
Marie SaliouLionnel Geoffrois, Marie-Christine Kaminsky, Institut de Cancérologie de Lorraine, Vandoeuvre Lès Nancy; Laurent Martin, Centre Guillaume le Conquérant; Dominique De Raucourt, Bernard Gery, Centre François Baclesse; Emmanuel Babin, Hopital Universitaire, Caen; Xu Shan Sun, Joëlle Buffet, Centre Hospitalier Universitaire de Besançon, Besançon; Hôpital de Mulhouse, Mulhouse; Yungan Tao, Gustave-Roussy Institute, Villejuif; Philippe Maingon, Centre François Leclercq, Leclercq; Yoann Pointreau, Cédric Lafond, Marie-Hélène Calais, Pascal Garaud, Centre Jean Bernard, Le Mans; Centre Hospitalier Universitaire de Tours, Tours; Christian Sire, Centre Hospitalier de Lorient, Lorient; Claude Tuchais, Eric Jadaud, Centre Paul Papin, Angers; Alexandre Coutte, Centre Hospitalier Universitaire Amiens, Amiens; Frédéric Rolland, Centre René Gauducheau, Saint Herblain; Marc Alfonsi, Clinique Sainte Catherine, Avignon; Michel Lapeyre, Centre Jean Perrin, Clermont; Marie Saliou, Clinique Mutualiste, Saint Nazaire; Ayman Zawadi, Centre Hospitalier de La Roche-sur-Yon, La Roche-sur-Yon; Jean-Marc Tourani, Centre Hospitalier Universitaire, Poitiers, Poitiers; Cédric Khoury, Centre Saint Louis; Pierre Guillet, Hôpital Font-Pré, Toulon, Toulon; Ali Hasbini, Hopital de Saint Brieuc, Saint Brieuc; François Guichard, Polyclinique de Bordeaux-Nord, Bordeaux; Christian Borel, Centre Paul Strauss, Strasbourg, France; Anne Rose Henry, Hôpital Montigny le Tilleul, Montigny-le-Tilleul; Nicolas Meert, Centre Hospitalier de Charlebois, Charlebois, Belgium; and Jean Bourhis, Centre Hospitalier Universitaire Vaudois Lausanne, Lausanne, Switzerland.
Cédric LafondLionnel Geoffrois, Marie-Christine Kaminsky, Institut de Cancérologie de Lorraine, Vandoeuvre Lès Nancy; Laurent Martin, Centre Guillaume le Conquérant; Dominique De Raucourt, Bernard Gery, Centre François Baclesse; Emmanuel Babin, Hopital Universitaire, Caen; Xu Shan Sun, Joëlle Buffet, Centre Hospitalier Universitaire de Besançon, Besançon; Hôpital de Mulhouse, Mulhouse; Yungan Tao, Gustave-Roussy Institute, Villejuif; Philippe Maingon, Centre François Leclercq, Leclercq; Yoann Pointreau, Cédric Lafond, Marie-Hélène Calais, Pascal Garaud, Centre Jean Bernard, Le Mans; Centre Hospitalier Universitaire de Tours, Tours; Christian Sire, Centre Hospitalier de Lorient, Lorient; Claude Tuchais, Eric Jadaud, Centre Paul Papin, Angers; Alexandre Coutte, Centre Hospitalier Universitaire Amiens, Amiens; Frédéric Rolland, Centre René Gauducheau, Saint Herblain; Marc Alfonsi, Clinique Sainte Catherine, Avignon; Michel Lapeyre, Centre Jean Perrin, Clermont; Marie Saliou, Clinique Mutualiste, Saint Nazaire; Ayman Zawadi, Centre Hospitalier de La Roche-sur-Yon, La Roche-sur-Yon; Jean-Marc Tourani, Centre Hospitalier Universitaire, Poitiers, Poitiers; Cédric Khoury, Centre Saint Louis; Pierre Guillet, Hôpital Font-Pré, Toulon, Toulon; Ali Hasbini, Hopital de Saint Brieuc, Saint Brieuc; François Guichard, Polyclinique de Bordeaux-Nord, Bordeaux; Christian Borel, Centre Paul Strauss, Strasbourg, France; Anne Rose Henry, Hôpital Montigny le Tilleul, Montigny-le-Tilleul; Nicolas Meert, Centre Hospitalier de Charlebois, Charlebois, Belgium; and Jean Bourhis, Centre Hospitalier Universitaire Vaudois Lausanne, Lausanne, Switzerland.
Eric JadaudLionnel Geoffrois, Marie-Christine Kaminsky, Institut de Cancérologie de Lorraine, Vandoeuvre Lès Nancy; Laurent Martin, Centre Guillaume le Conquérant; Dominique De Raucourt, Bernard Gery, Centre François Baclesse; Emmanuel Babin, Hopital Universitaire, Caen; Xu Shan Sun, Joëlle Buffet, Centre Hospitalier Universitaire de Besançon, Besançon; Hôpital de Mulhouse, Mulhouse; Yungan Tao, Gustave-Roussy Institute, Villejuif; Philippe Maingon, Centre François Leclercq, Leclercq; Yoann Pointreau, Cédric Lafond, Marie-Hélène Calais, Pascal Garaud, Centre Jean Bernard, Le Mans; Centre Hospitalier Universitaire de Tours, Tours; Christian Sire, Centre Hospitalier de Lorient, Lorient; Claude Tuchais, Eric Jadaud, Centre Paul Papin, Angers; Alexandre Coutte, Centre Hospitalier Universitaire Amiens, Amiens; Frédéric Rolland, Centre René Gauducheau, Saint Herblain; Marc Alfonsi, Clinique Sainte Catherine, Avignon; Michel Lapeyre, Centre Jean Perrin, Clermont; Marie Saliou, Clinique Mutualiste, Saint Nazaire; Ayman Zawadi, Centre Hospitalier de La Roche-sur-Yon, La Roche-sur-Yon; Jean-Marc Tourani, Centre Hospitalier Universitaire, Poitiers, Poitiers; Cédric Khoury, Centre Saint Louis; Pierre Guillet, Hôpital Font-Pré, Toulon, Toulon; Ali Hasbini, Hopital de Saint Brieuc, Saint Brieuc; François Guichard, Polyclinique de Bordeaux-Nord, Bordeaux; Christian Borel, Centre Paul Strauss, Strasbourg, France; Anne Rose Henry, Hôpital Montigny le Tilleul, Montigny-le-Tilleul; Nicolas Meert, Centre Hospitalier de Charlebois, Charlebois, Belgium; and Jean Bourhis, Centre Hospitalier Universitaire Vaudois Lausanne, Lausanne, Switzerland.
Bernard GeryLionnel Geoffrois, Marie-Christine Kaminsky, Institut de Cancérologie de Lorraine, Vandoeuvre Lès Nancy; Laurent Martin, Centre Guillaume le Conquérant; Dominique De Raucourt, Bernard Gery, Centre François Baclesse; Emmanuel Babin, Hopital Universitaire, Caen; Xu Shan Sun, Joëlle Buffet, Centre Hospitalier Universitaire de Besançon, Besançon; Hôpital de Mulhouse, Mulhouse; Yungan Tao, Gustave-Roussy Institute, Villejuif; Philippe Maingon, Centre François Leclercq, Leclercq; Yoann Pointreau, Cédric Lafond, Marie-Hélène Calais, Pascal Garaud, Centre Jean Bernard, Le Mans; Centre Hospitalier Universitaire de Tours, Tours; Christian Sire, Centre Hospitalier de Lorient, Lorient; Claude Tuchais, Eric Jadaud, Centre Paul Papin, Angers; Alexandre Coutte, Centre Hospitalier Universitaire Amiens, Amiens; Frédéric Rolland, Centre René Gauducheau, Saint Herblain; Marc Alfonsi, Clinique Sainte Catherine, Avignon; Michel Lapeyre, Centre Jean Perrin, Clermont; Marie Saliou, Clinique Mutualiste, Saint Nazaire; Ayman Zawadi, Centre Hospitalier de La Roche-sur-Yon, La Roche-sur-Yon; Jean-Marc Tourani, Centre Hospitalier Universitaire, Poitiers, Poitiers; Cédric Khoury, Centre Saint Louis; Pierre Guillet, Hôpital Font-Pré, Toulon, Toulon; Ali Hasbini, Hopital de Saint Brieuc, Saint Brieuc; François Guichard, Polyclinique de Bordeaux-Nord, Bordeaux; Christian Borel, Centre Paul Strauss, Strasbourg, France; Anne Rose Henry, Hôpital Montigny le Tilleul, Montigny-le-Tilleul; Nicolas Meert, Centre Hospitalier de Charlebois, Charlebois, Belgium; and Jean Bourhis, Centre Hospitalier Universitaire Vaudois Lausanne, Lausanne, Switzerland.
Ayman ZawadiLionnel Geoffrois, Marie-Christine Kaminsky, Institut de Cancérologie de Lorraine, Vandoeuvre Lès Nancy; Laurent Martin, Centre Guillaume le Conquérant; Dominique De Raucourt, Bernard Gery, Centre François Baclesse; Emmanuel Babin, Hopital Universitaire, Caen; Xu Shan Sun, Joëlle Buffet, Centre Hospitalier Universitaire de Besançon, Besançon; Hôpital de Mulhouse, Mulhouse; Yungan Tao, Gustave-Roussy Institute, Villejuif; Philippe Maingon, Centre François Leclercq, Leclercq; Yoann Pointreau, Cédric Lafond, Marie-Hélène Calais, Pascal Garaud, Centre Jean Bernard, Le Mans; Centre Hospitalier Universitaire de Tours, Tours; Christian Sire, Centre Hospitalier de Lorient, Lorient; Claude Tuchais, Eric Jadaud, Centre Paul Papin, Angers; Alexandre Coutte, Centre Hospitalier Universitaire Amiens, Amiens; Frédéric Rolland, Centre René Gauducheau, Saint Herblain; Marc Alfonsi, Clinique Sainte Catherine, Avignon; Michel Lapeyre, Centre Jean Perrin, Clermont; Marie Saliou, Clinique Mutualiste, Saint Nazaire; Ayman Zawadi, Centre Hospitalier de La Roche-sur-Yon, La Roche-sur-Yon; Jean-Marc Tourani, Centre Hospitalier Universitaire, Poitiers, Poitiers; Cédric Khoury, Centre Saint Louis; Pierre Guillet, Hôpital Font-Pré, Toulon, Toulon; Ali Hasbini, Hopital de Saint Brieuc, Saint Brieuc; François Guichard, Polyclinique de Bordeaux-Nord, Bordeaux; Christian Borel, Centre Paul Strauss, Strasbourg, France; Anne Rose Henry, Hôpital Montigny le Tilleul, Montigny-le-Tilleul; Nicolas Meert, Centre Hospitalier de Charlebois, Charlebois, Belgium; and Jean Bourhis, Centre Hospitalier Universitaire Vaudois Lausanne, Lausanne, Switzerland.
Jean-Marc TouraniLionnel Geoffrois, Marie-Christine Kaminsky, Institut de Cancérologie de Lorraine, Vandoeuvre Lès Nancy; Laurent Martin, Centre Guillaume le Conquérant; Dominique De Raucourt, Bernard Gery, Centre François Baclesse; Emmanuel Babin, Hopital Universitaire, Caen; Xu Shan Sun, Joëlle Buffet, Centre Hospitalier Universitaire de Besançon, Besançon; Hôpital de Mulhouse, Mulhouse; Yungan Tao, Gustave-Roussy Institute, Villejuif; Philippe Maingon, Centre François Leclercq, Leclercq; Yoann Pointreau, Cédric Lafond, Marie-Hélène Calais, Pascal Garaud, Centre Jean Bernard, Le Mans; Centre Hospitalier Universitaire de Tours, Tours; Christian Sire, Centre Hospitalier de Lorient, Lorient; Claude Tuchais, Eric Jadaud, Centre Paul Papin, Angers; Alexandre Coutte, Centre Hospitalier Universitaire Amiens, Amiens; Frédéric Rolland, Centre René Gauducheau, Saint Herblain; Marc Alfonsi, Clinique Sainte Catherine, Avignon; Michel Lapeyre, Centre Jean Perrin, Clermont; Marie Saliou, Clinique Mutualiste, Saint Nazaire; Ayman Zawadi, Centre Hospitalier de La Roche-sur-Yon, La Roche-sur-Yon; Jean-Marc Tourani, Centre Hospitalier Universitaire, Poitiers, Poitiers; Cédric Khoury, Centre Saint Louis; Pierre Guillet, Hôpital Font-Pré, Toulon, Toulon; Ali Hasbini, Hopital de Saint Brieuc, Saint Brieuc; François Guichard, Polyclinique de Bordeaux-Nord, Bordeaux; Christian Borel, Centre Paul Strauss, Strasbourg, France; Anne Rose Henry, Hôpital Montigny le Tilleul, Montigny-le-Tilleul; Nicolas Meert, Centre Hospitalier de Charlebois, Charlebois, Belgium; and Jean Bourhis, Centre Hospitalier Universitaire Vaudois Lausanne, Lausanne, Switzerland.
Cédric KhouryLionnel Geoffrois, Marie-Christine Kaminsky, Institut de Cancérologie de Lorraine, Vandoeuvre Lès Nancy; Laurent Martin, Centre Guillaume le Conquérant; Dominique De Raucourt, Bernard Gery, Centre François Baclesse; Emmanuel Babin, Hopital Universitaire, Caen; Xu Shan Sun, Joëlle Buffet, Centre Hospitalier Universitaire de Besançon, Besançon; Hôpital de Mulhouse, Mulhouse; Yungan Tao, Gustave-Roussy Institute, Villejuif; Philippe Maingon, Centre François Leclercq, Leclercq; Yoann Pointreau, Cédric Lafond, Marie-Hélène Calais, Pascal Garaud, Centre Jean Bernard, Le Mans; Centre Hospitalier Universitaire de Tours, Tours; Christian Sire, Centre Hospitalier de Lorient, Lorient; Claude Tuchais, Eric Jadaud, Centre Paul Papin, Angers; Alexandre Coutte, Centre Hospitalier Universitaire Amiens, Amiens; Frédéric Rolland, Centre René Gauducheau, Saint Herblain; Marc Alfonsi, Clinique Sainte Catherine, Avignon; Michel Lapeyre, Centre Jean Perrin, Clermont; Marie Saliou, Clinique Mutualiste, Saint Nazaire; Ayman Zawadi, Centre Hospitalier de La Roche-sur-Yon, La Roche-sur-Yon; Jean-Marc Tourani, Centre Hospitalier Universitaire, Poitiers, Poitiers; Cédric Khoury, Centre Saint Louis; Pierre Guillet, Hôpital Font-Pré, Toulon, Toulon; Ali Hasbini, Hopital de Saint Brieuc, Saint Brieuc; François Guichard, Polyclinique de Bordeaux-Nord, Bordeaux; Christian Borel, Centre Paul Strauss, Strasbourg, France; Anne Rose Henry, Hôpital Montigny le Tilleul, Montigny-le-Tilleul; Nicolas Meert, Centre Hospitalier de Charlebois, Charlebois, Belgium; and Jean Bourhis, Centre Hospitalier Universitaire Vaudois Lausanne, Lausanne, Switzerland.
Anne Rose HenryLionnel Geoffrois, Marie-Christine Kaminsky, Institut de Cancérologie de Lorraine, Vandoeuvre Lès Nancy; Laurent Martin, Centre Guillaume le Conquérant; Dominique De Raucourt, Bernard Gery, Centre François Baclesse; Emmanuel Babin, Hopital Universitaire, Caen; Xu Shan Sun, Joëlle Buffet, Centre Hospitalier Universitaire de Besançon, Besançon; Hôpital de Mulhouse, Mulhouse; Yungan Tao, Gustave-Roussy Institute, Villejuif; Philippe Maingon, Centre François Leclercq, Leclercq; Yoann Pointreau, Cédric Lafond, Marie-Hélène Calais, Pascal Garaud, Centre Jean Bernard, Le Mans; Centre Hospitalier Universitaire de Tours, Tours; Christian Sire, Centre Hospitalier de Lorient, Lorient; Claude Tuchais, Eric Jadaud, Centre Paul Papin, Angers; Alexandre Coutte, Centre Hospitalier Universitaire Amiens, Amiens; Frédéric Rolland, Centre René Gauducheau, Saint Herblain; Marc Alfonsi, Clinique Sainte Catherine, Avignon; Michel Lapeyre, Centre Jean Perrin, Clermont; Marie Saliou, Clinique Mutualiste, Saint Nazaire; Ayman Zawadi, Centre Hospitalier de La Roche-sur-Yon, La Roche-sur-Yon; Jean-Marc Tourani, Centre Hospitalier Universitaire, Poitiers, Poitiers; Cédric Khoury, Centre Saint Louis; Pierre Guillet, Hôpital Font-Pré, Toulon, Toulon; Ali Hasbini, Hopital de Saint Brieuc, Saint Brieuc; François Guichard, Polyclinique de Bordeaux-Nord, Bordeaux; Christian Borel, Centre Paul Strauss, Strasbourg, France; Anne Rose Henry, Hôpital Montigny le Tilleul, Montigny-le-Tilleul; Nicolas Meert, Centre Hospitalier de Charlebois, Charlebois, Belgium; and Jean Bourhis, Centre Hospitalier Universitaire Vaudois Lausanne, Lausanne, Switzerland.
Ali HasbiniLionnel Geoffrois, Marie-Christine Kaminsky, Institut de Cancérologie de Lorraine, Vandoeuvre Lès Nancy; Laurent Martin, Centre Guillaume le Conquérant; Dominique De Raucourt, Bernard Gery, Centre François Baclesse; Emmanuel Babin, Hopital Universitaire, Caen; Xu Shan Sun, Joëlle Buffet, Centre Hospitalier Universitaire de Besançon, Besançon; Hôpital de Mulhouse, Mulhouse; Yungan Tao, Gustave-Roussy Institute, Villejuif; Philippe Maingon, Centre François Leclercq, Leclercq; Yoann Pointreau, Cédric Lafond, Marie-Hélène Calais, Pascal Garaud, Centre Jean Bernard, Le Mans; Centre Hospitalier Universitaire de Tours, Tours; Christian Sire, Centre Hospitalier de Lorient, Lorient; Claude Tuchais, Eric Jadaud, Centre Paul Papin, Angers; Alexandre Coutte, Centre Hospitalier Universitaire Amiens, Amiens; Frédéric Rolland, Centre René Gauducheau, Saint Herblain; Marc Alfonsi, Clinique Sainte Catherine, Avignon; Michel Lapeyre, Centre Jean Perrin, Clermont; Marie Saliou, Clinique Mutualiste, Saint Nazaire; Ayman Zawadi, Centre Hospitalier de La Roche-sur-Yon, La Roche-sur-Yon; Jean-Marc Tourani, Centre Hospitalier Universitaire, Poitiers, Poitiers; Cédric Khoury, Centre Saint Louis; Pierre Guillet, Hôpital Font-Pré, Toulon, Toulon; Ali Hasbini, Hopital de Saint Brieuc, Saint Brieuc; François Guichard, Polyclinique de Bordeaux-Nord, Bordeaux; Christian Borel, Centre Paul Strauss, Strasbourg, France; Anne Rose Henry, Hôpital Montigny le Tilleul, Montigny-le-Tilleul; Nicolas Meert, Centre Hospitalier de Charlebois, Charlebois, Belgium; and Jean Bourhis, Centre Hospitalier Universitaire Vaudois Lausanne, Lausanne, Switzerland.
François GuichardLionnel Geoffrois, Marie-Christine Kaminsky, Institut de Cancérologie de Lorraine, Vandoeuvre Lès Nancy; Laurent Martin, Centre Guillaume le Conquérant; Dominique De Raucourt, Bernard Gery, Centre François Baclesse; Emmanuel Babin, Hopital Universitaire, Caen; Xu Shan Sun, Joëlle Buffet, Centre Hospitalier Universitaire de Besançon, Besançon; Hôpital de Mulhouse, Mulhouse; Yungan Tao, Gustave-Roussy Institute, Villejuif; Philippe Maingon, Centre François Leclercq, Leclercq; Yoann Pointreau, Cédric Lafond, Marie-Hélène Calais, Pascal Garaud, Centre Jean Bernard, Le Mans; Centre Hospitalier Universitaire de Tours, Tours; Christian Sire, Centre Hospitalier de Lorient, Lorient; Claude Tuchais, Eric Jadaud, Centre Paul Papin, Angers; Alexandre Coutte, Centre Hospitalier Universitaire Amiens, Amiens; Frédéric Rolland, Centre René Gauducheau, Saint Herblain; Marc Alfonsi, Clinique Sainte Catherine, Avignon; Michel Lapeyre, Centre Jean Perrin, Clermont; Marie Saliou, Clinique Mutualiste, Saint Nazaire; Ayman Zawadi, Centre Hospitalier de La Roche-sur-Yon, La Roche-sur-Yon; Jean-Marc Tourani, Centre Hospitalier Universitaire, Poitiers, Poitiers; Cédric Khoury, Centre Saint Louis; Pierre Guillet, Hôpital Font-Pré, Toulon, Toulon; Ali Hasbini, Hopital de Saint Brieuc, Saint Brieuc; François Guichard, Polyclinique de Bordeaux-Nord, Bordeaux; Christian Borel, Centre Paul Strauss, Strasbourg, France; Anne Rose Henry, Hôpital Montigny le Tilleul, Montigny-le-Tilleul; Nicolas Meert, Centre Hospitalier de Charlebois, Charlebois, Belgium; and Jean Bourhis, Centre Hospitalier Universitaire Vaudois Lausanne, Lausanne, Switzerland.
Christian BorelLionnel Geoffrois, Marie-Christine Kaminsky, Institut de Cancérologie de Lorraine, Vandoeuvre Lès Nancy; Laurent Martin, Centre Guillaume le Conquérant; Dominique De Raucourt, Bernard Gery, Centre François Baclesse; Emmanuel Babin, Hopital Universitaire, Caen; Xu Shan Sun, Joëlle Buffet, Centre Hospitalier Universitaire de Besançon, Besançon; Hôpital de Mulhouse, Mulhouse; Yungan Tao, Gustave-Roussy Institute, Villejuif; Philippe Maingon, Centre François Leclercq, Leclercq; Yoann Pointreau, Cédric Lafond, Marie-Hélène Calais, Pascal Garaud, Centre Jean Bernard, Le Mans; Centre Hospitalier Universitaire de Tours, Tours; Christian Sire, Centre Hospitalier de Lorient, Lorient; Claude Tuchais, Eric Jadaud, Centre Paul Papin, Angers; Alexandre Coutte, Centre Hospitalier Universitaire Amiens, Amiens; Frédéric Rolland, Centre René Gauducheau, Saint Herblain; Marc Alfonsi, Clinique Sainte Catherine, Avignon; Michel Lapeyre, Centre Jean Perrin, Clermont; Marie Saliou, Clinique Mutualiste, Saint Nazaire; Ayman Zawadi, Centre Hospitalier de La Roche-sur-Yon, La Roche-sur-Yon; Jean-Marc Tourani, Centre Hospitalier Universitaire, Poitiers, Poitiers; Cédric Khoury, Centre Saint Louis; Pierre Guillet, Hôpital Font-Pré, Toulon, Toulon; Ali Hasbini, Hopital de Saint Brieuc, Saint Brieuc; François Guichard, Polyclinique de Bordeaux-Nord, Bordeaux; Christian Borel, Centre Paul Strauss, Strasbourg, France; Anne Rose Henry, Hôpital Montigny le Tilleul, Montigny-le-Tilleul; Nicolas Meert, Centre Hospitalier de Charlebois, Charlebois, Belgium; and Jean Bourhis, Centre Hospitalier Universitaire Vaudois Lausanne, Lausanne, Switzerland.
Nicolas MeertLionnel Geoffrois, Marie-Christine Kaminsky, Institut de Cancérologie de Lorraine, Vandoeuvre Lès Nancy; Laurent Martin, Centre Guillaume le Conquérant; Dominique De Raucourt, Bernard Gery, Centre François Baclesse; Emmanuel Babin, Hopital Universitaire, Caen; Xu Shan Sun, Joëlle Buffet, Centre Hospitalier Universitaire de Besançon, Besançon; Hôpital de Mulhouse, Mulhouse; Yungan Tao, Gustave-Roussy Institute, Villejuif; Philippe Maingon, Centre François Leclercq, Leclercq; Yoann Pointreau, Cédric Lafond, Marie-Hélène Calais, Pascal Garaud, Centre Jean Bernard, Le Mans; Centre Hospitalier Universitaire de Tours, Tours; Christian Sire, Centre Hospitalier de Lorient, Lorient; Claude Tuchais, Eric Jadaud, Centre Paul Papin, Angers; Alexandre Coutte, Centre Hospitalier Universitaire Amiens, Amiens; Frédéric Rolland, Centre René Gauducheau, Saint Herblain; Marc Alfonsi, Clinique Sainte Catherine, Avignon; Michel Lapeyre, Centre Jean Perrin, Clermont; Marie Saliou, Clinique Mutualiste, Saint Nazaire; Ayman Zawadi, Centre Hospitalier de La Roche-sur-Yon, La Roche-sur-Yon; Jean-Marc Tourani, Centre Hospitalier Universitaire, Poitiers, Poitiers; Cédric Khoury, Centre Saint Louis; Pierre Guillet, Hôpital Font-Pré, Toulon, Toulon; Ali Hasbini, Hopital de Saint Brieuc, Saint Brieuc; François Guichard, Polyclinique de Bordeaux-Nord, Bordeaux; Christian Borel, Centre Paul Strauss, Strasbourg, France; Anne Rose Henry, Hôpital Montigny le Tilleul, Montigny-le-Tilleul; Nicolas Meert, Centre Hospitalier de Charlebois, Charlebois, Belgium; and Jean Bourhis, Centre Hospitalier Universitaire Vaudois Lausanne, Lausanne, Switzerland.
Pierre GuilletLionnel Geoffrois, Marie-Christine Kaminsky, Institut de Cancérologie de Lorraine, Vandoeuvre Lès Nancy; Laurent Martin, Centre Guillaume le Conquérant; Dominique De Raucourt, Bernard Gery, Centre François Baclesse; Emmanuel Babin, Hopital Universitaire, Caen; Xu Shan Sun, Joëlle Buffet, Centre Hospitalier Universitaire de Besançon, Besançon; Hôpital de Mulhouse, Mulhouse; Yungan Tao, Gustave-Roussy Institute, Villejuif; Philippe Maingon, Centre François Leclercq, Leclercq; Yoann Pointreau, Cédric Lafond, Marie-Hélène Calais, Pascal Garaud, Centre Jean Bernard, Le Mans; Centre Hospitalier Universitaire de Tours, Tours; Christian Sire, Centre Hospitalier de Lorient, Lorient; Claude Tuchais, Eric Jadaud, Centre Paul Papin, Angers; Alexandre Coutte, Centre Hospitalier Universitaire Amiens, Amiens; Frédéric Rolland, Centre René Gauducheau, Saint Herblain; Marc Alfonsi, Clinique Sainte Catherine, Avignon; Michel Lapeyre, Centre Jean Perrin, Clermont; Marie Saliou, Clinique Mutualiste, Saint Nazaire; Ayman Zawadi, Centre Hospitalier de La Roche-sur-Yon, La Roche-sur-Yon; Jean-Marc Tourani, Centre Hospitalier Universitaire, Poitiers, Poitiers; Cédric Khoury, Centre Saint Louis; Pierre Guillet, Hôpital Font-Pré, Toulon, Toulon; Ali Hasbini, Hopital de Saint Brieuc, Saint Brieuc; François Guichard, Polyclinique de Bordeaux-Nord, Bordeaux; Christian Borel, Centre Paul Strauss, Strasbourg, France; Anne Rose Henry, Hôpital Montigny le Tilleul, Montigny-le-Tilleul; Nicolas Meert, Centre Hospitalier de Charlebois, Charlebois, Belgium; and Jean Bourhis, Centre Hospitalier Universitaire Vaudois Lausanne, Lausanne, Switzerland.
Marie-Hélène CalaisLionnel Geoffrois, Marie-Christine Kaminsky, Institut de Cancérologie de Lorraine, Vandoeuvre Lès Nancy; Laurent Martin, Centre Guillaume le Conquérant; Dominique De Raucourt, Bernard Gery, Centre François Baclesse; Emmanuel Babin, Hopital Universitaire, Caen; Xu Shan Sun, Joëlle Buffet, Centre Hospitalier Universitaire de Besançon, Besançon; Hôpital de Mulhouse, Mulhouse; Yungan Tao, Gustave-Roussy Institute, Villejuif; Philippe Maingon, Centre François Leclercq, Leclercq; Yoann Pointreau, Cédric Lafond, Marie-Hélène Calais, Pascal Garaud, Centre Jean Bernard, Le Mans; Centre Hospitalier Universitaire de Tours, Tours; Christian Sire, Centre Hospitalier de Lorient, Lorient; Claude Tuchais, Eric Jadaud, Centre Paul Papin, Angers; Alexandre Coutte, Centre Hospitalier Universitaire Amiens, Amiens; Frédéric Rolland, Centre René Gauducheau, Saint Herblain; Marc Alfonsi, Clinique Sainte Catherine, Avignon; Michel Lapeyre, Centre Jean Perrin, Clermont; Marie Saliou, Clinique Mutualiste, Saint Nazaire; Ayman Zawadi, Centre Hospitalier de La Roche-sur-Yon, La Roche-sur-Yon; Jean-Marc Tourani, Centre Hospitalier Universitaire, Poitiers, Poitiers; Cédric Khoury, Centre Saint Louis; Pierre Guillet, Hôpital Font-Pré, Toulon, Toulon; Ali Hasbini, Hopital de Saint Brieuc, Saint Brieuc; François Guichard, Polyclinique de Bordeaux-Nord, Bordeaux; Christian Borel, Centre Paul Strauss, Strasbourg, France; Anne Rose Henry, Hôpital Montigny le Tilleul, Montigny-le-Tilleul; Nicolas Meert, Centre Hospitalier de Charlebois, Charlebois, Belgium; and Jean Bourhis, Centre Hospitalier Universitaire Vaudois Lausanne, Lausanne, Switzerland.
Pascal GaraudLionnel Geoffrois, Marie-Christine Kaminsky, Institut de Cancérologie de Lorraine, Vandoeuvre Lès Nancy; Laurent Martin, Centre Guillaume le Conquérant; Dominique De Raucourt, Bernard Gery, Centre François Baclesse; Emmanuel Babin, Hopital Universitaire, Caen; Xu Shan Sun, Joëlle Buffet, Centre Hospitalier Universitaire de Besançon, Besançon; Hôpital de Mulhouse, Mulhouse; Yungan Tao, Gustave-Roussy Institute, Villejuif; Philippe Maingon, Centre François Leclercq, Leclercq; Yoann Pointreau, Cédric Lafond, Marie-Hélène Calais, Pascal Garaud, Centre Jean Bernard, Le Mans; Centre Hospitalier Universitaire de Tours, Tours; Christian Sire, Centre Hospitalier de Lorient, Lorient; Claude Tuchais, Eric Jadaud, Centre Paul Papin, Angers; Alexandre Coutte, Centre Hospitalier Universitaire Amiens, Amiens; Frédéric Rolland, Centre René Gauducheau, Saint Herblain; Marc Alfonsi, Clinique Sainte Catherine, Avignon; Michel Lapeyre, Centre Jean Perrin, Clermont; Marie Saliou, Clinique Mutualiste, Saint Nazaire; Ayman Zawadi, Centre Hospitalier de La Roche-sur-Yon, La Roche-sur-Yon; Jean-Marc Tourani, Centre Hospitalier Universitaire, Poitiers, Poitiers; Cédric Khoury, Centre Saint Louis; Pierre Guillet, Hôpital Font-Pré, Toulon, Toulon; Ali Hasbini, Hopital de Saint Brieuc, Saint Brieuc; François Guichard, Polyclinique de Bordeaux-Nord, Bordeaux; Christian Borel, Centre Paul Strauss, Strasbourg, France; Anne Rose Henry, Hôpital Montigny le Tilleul, Montigny-le-Tilleul; Nicolas Meert, Centre Hospitalier de Charlebois, Charlebois, Belgium; and Jean Bourhis, Centre Hospitalier Universitaire Vaudois Lausanne, Lausanne, Switzerland.
Jean BourhisLionnel Geoffrois, Marie-Christine Kaminsky, Institut de Cancérologie de Lorraine, Vandoeuvre Lès Nancy; Laurent Martin, Centre Guillaume le Conquérant; Dominique De Raucourt, Bernard Gery, Centre François Baclesse; Emmanuel Babin, Hopital Universitaire, Caen; Xu Shan Sun, Joëlle Buffet, Centre Hospitalier Universitaire de Besançon, Besançon; Hôpital de Mulhouse, Mulhouse; Yungan Tao, Gustave-Roussy Institute, Villejuif; Philippe Maingon, Centre François Leclercq, Leclercq; Yoann Pointreau, Cédric Lafond, Marie-Hélène Calais, Pascal Garaud, Centre Jean Bernard, Le Mans; Centre Hospitalier Universitaire de Tours, Tours; Christian Sire, Centre Hospitalier de Lorient, Lorient; Claude Tuchais, Eric Jadaud, Centre Paul Papin, Angers; Alexandre Coutte, Centre Hospitalier Universitaire Amiens, Amiens; Frédéric Rolland, Centre René Gauducheau, Saint Herblain; Marc Alfonsi, Clinique Sainte Catherine, Avignon; Michel Lapeyre, Centre Jean Perrin, Clermont; Marie Saliou, Clinique Mutualiste, Saint Nazaire; Ayman Zawadi, Centre Hospitalier de La Roche-sur-Yon, La Roche-sur-Yon; Jean-Marc Tourani, Centre Hospitalier Universitaire, Poitiers, Poitiers; Cédric Khoury, Centre Saint Louis; Pierre Guillet, Hôpital Font-Pré, Toulon, Toulon; Ali Hasbini, Hopital de Saint Brieuc, Saint Brieuc; François Guichard, Polyclinique de Bordeaux-Nord, Bordeaux; Christian Borel, Centre Paul Strauss, Strasbourg, France; Anne Rose Henry, Hôpital Montigny le Tilleul, Montigny-le-Tilleul; Nicolas Meert, Centre Hospitalier de Charlebois, Charlebois, Belgium; and Jean Bourhis, Centre Hospitalier Universitaire Vaudois Lausanne, Lausanne, Switzerland.
Centre Hospitalier Universitaire de Besançon · FR
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeBoth concurrent chemoradiotherapy (CT-RT) and cetuximab radiotherapy (cetux-RT) have been established as the standard of care for the treatment of locally advanced squamous cell carcinoma of the head and neck. It was not known whether the addition of induction chemotherapy before cetux-RT could improve outcomes compared with standard of care CT-RT. PATIENTS AND
methodsThe current trial was restricted to patients with nonmetastatic N2b, N2c, or N3 squamous cell carcinoma of the head and neck and fit for taxotere, cisplatin, fluorouracil (TPF). Patients were randomly assigned to receive three cycles of TPF followed by cetux-RT versus concurrent carboplatin fluorouracil and RT as recommended in National Comprehensive Cancer Network guidelines. The trial was powered to detect a hazard ratio (HR) of 0.66 in favor of TPF plus cetux-RT for progression-free survival at 2 years. The inclusion of 180 patients per arm was needed to achieve 80% power at a two-sided significance level of .05.
resultsBetween 2009 and 2013, 370 patients were included. All patients and tumors characteristics were well balanced between arms. There were more cases of grade 3 and 4 neutropenia in the induction arm, and the induction TPF was associated with 6.6% treatment-related deaths. With a median follow-up of 2.8 years, 2-year progression-free survival was not different between both arms (CT-RT, 0.38
conclusionInduction TPF followed by cetux-RT did not improve outcomes compared with CT-RT in a population of patients with advanced cervical lymphadenopathy.
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Registered trials
NCT05517330ClinicalTrials.gov
NCT06494189ClinicalTrials.gov
NCT06741982ClinicalTrials.gov
NCT06804850ClinicalTrials.gov
NCT07040956ClinicalTrials.gov
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