Evidence map›Paper›PMID 30015616›Full record

ArticleeLife2018

Radially patterned cell behaviours during tube budding from an epithelium.

Yara E Sanchez-Corrales, Guy B Blanchard, Katja Röper

Abstract read
In one paragraph

Article in eLife, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed.

  1. Article
  2. Opposing Activity at the Apical Surface: An Antagonistic Collaboration Between Crumbs and Myosin II Determines Organ Shape.BioEssays : news and reviews in molecular, cellular and developmental biology · 2026
    Review
  3. Actuation of Cell Layers in Three Dimensions.Advanced materials (Deerfield Beach, Fla.) · 2026
    Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. The dynamics of tubulogenesis in development and disease.Development (Cambridge, England) · 2025
    Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Yara E Sanchez-CorralesMRC Laboratory of Molecular Biology, Cambridge, United Kingdom.ORCID http://orcid.org/0000-0003-1438-1994
Guy B BlanchardDepartment of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, United Kingdom.ORCID http://orcid.org/0000-0002-3689-0522
Katja RöperMRC Laboratory of Molecular Biology, Cambridge, United Kingdom.ORCID http://orcid.org/0000-0002-3361-766X

Funding

Biotechnology and Biological Sciences Research Council BB/J010278/1Medical Research Council MC_UP_1201/11Medical Research Council U105178780Wellcome TrustWellcome Trust 099234/Z/12/ZWellcome Trust 100329/Z/12/Z
6 · The paper itself

Abstract

The budding of tubular organs from flat epithelial sheets is a vital morphogenetic process. Cell behaviours that drive such processes are only starting to be unraveled. Using live-imaging and novel morphometric methods, we show that in addition to apical constriction, radially oriented directional intercalation of cells plays a major contribution to early stages of invagination of the salivary gland tube in the

Indexed as

MorphogenesisAnimalsCell PolarityCell ShapeDrosophila melanogasterEmbryo, NonmammalianEpithelial CellsEpitheliumFluorescenceImaging, Three-DimensionalMutationMyosin Type IISalivary GlandsTime-Lapse ImagingMyosin Type IIcell biologycell shapedevelopmental biologyD. melanogasterepitheliamorphogenesisorganogenesisquantitative analysisradial polarity

Identifiers

PMID30015616
PMCPMC6089598

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.