Evidence map›Paper›PMID 30015461›Full record

ArticlePolish journal of microbiology2018

Global Transcriptome Changes of Biofilm-Forming Staphylococcus epidermidis Responding to Total Alkaloids of Sophorea alopecuroides.

Cui-Ping Guan, Hui-Xia Luo, H E Fang, Xue-Zhang Zhou

Abstract read
In one paragraph

Article in Polish journal of microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Aloperin improves liver non-alcoholic steatohepatitisArchives of medical science : AMS · 2025
    Article
  2. Total alkaloids ofChinese herbal medicines · 2020
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Cui-Ping GuanKey Laboratory of the Ministry of Education for the Conservation and Utilization of Special Biological Resources in Western China, Ningxia University,Yinchuan, Ningxia,China.
Hui-Xia LuoKey Laboratory of the Ministry of Education for the Conservation and Utilization of Special Biological Resources in Western China, Ningxia University,Yinchuan, Ningxia,China.
H E FangKey Laboratory of the Ministry of Education for the Conservation and Utilization of Special Biological Resources in Western China, Ningxia University,Yinchuan, Ningxia,China.
Xue-Zhang ZhouKey Laboratory of the Ministry of Education for the Conservation and Utilization of Special Biological Resources in Western China, Ningxia University,Yinchuan, Ningxia,China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Transcriptome changes of biofilm-forming Staphylococcus epidermidis response to total alkaloids of Sophorea alopecuroides was observed. Bioinformatic analyses were further used to compare the differential gene expression between control and the treated samples. It was found that 282 genes were differentially expressed, with 92 up-regulated and 190 down-regulated. These involved down-regulation of the sulfur metabolism pathway. It was suggested that inhibitory effects on Staphylococcus epidermidis and its biofilm formation of the total alkaloids of S. alopecuroides was mainly due to the regulation of the sulfur metabolism pathways of S. epidermidis.

Indexed as

TranscriptomeAlkaloidsAnti-Bacterial AgentsBacterial ProteinsBiofilmsComputational BiologyGene Expression Regulation, BacterialMetabolic Networks and PathwaysSophoraStaphylococcus epidermidisSulfurAlkaloidsAnti-Bacterial AgentsBacterial ProteinsSulfurStaphylococcus epidermidissulfur metabolismtotal alkaloids of Sophorea alopecuroidestranscriptome

Identifiers

PMID30015461
PMCPMC7256688

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.