ArticleHuman brain mapping2018
Functional cerebral asymmetry analyses reveal how the control system implements its flexibility.
Article in Human brain mapping, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.
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Who cites it
10 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Not All Stroop-Type Tasks Are Alike: Assessing the Impact of Stimulus Material, Task Design, and Cognitive Demand via Meta-analyses Across Neuroimaging Studies.Neuropsychology review · 2025Pooled it
- A meta-analysis of cognitive flexibility in aging: Perspective from functional network and lateralization.Human brain mapping · 2024Pooled it
- Frontal two-electrode transcranial direct current stimulation protocols may not affect performance on a combined flanker Go/No-Go task.Scientific reports · 2023Trial
- Functional divergence between the two cerebral hemispheres contributes to human fluid intelligence.Communications biology · 2025Article
- Modulation of rhythmic visual stimulation on left-right attentional asymmetry.Frontiers in neuroscience · 2023Article
- Cingulate cortex morphology impacts on neurofunctional activity and behavioral performance in interference tasks.Scientific reports · 2022Article
- Understanding cognitive control in aging: A brain network perspective.Frontiers in aging neuroscience · 2022Review
- Low frequency repetitive transcranial magnetic stimulation to the right dorsolateral prefrontal cortex engages thalamus, striatum, and the default mode network.Frontiers in neuroscience · 2022Article
- Involvement of the Right Dorsolateral Prefrontal Cortex in Numerical Rule Induction: A Transcranial Direct Current Stimulation Study.Frontiers in human neuroscience · 2020Article
- Functional cerebral asymmetry analyses reveal how the control system implements its flexibility.Human brain mapping · 2018Article
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4 authors.
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Abstract
The control system in human brain generally exerts the goal-directed regulation on a variety of mental processes. To deal with different control demands, these brain areas of the control system, especially the dorsolateral prefrontal cortex (DLPFC), may be flexibly recruited across different tasks. However, few studies have investigated how the flexibility of the control system is realized during cognitive control. Present study employed functional magnetic resonance imaging to examine the brain responses during two domain distinct conflict tasks (verbal color-word Stroop and visuospatial arrow flanker). The voxel-wise asymmetries in both functional activity and psychophysiological interaction (PPI) between these two tasks were compared. The results showed that the brain areas of control system were consistently activated in these two tasks. When considering functional cerebral asymmetries, the left DLPFC was dominantly activated during the Stroop task, while more symmetric DLPFC activation was found during the flanker task. The left DLPFC rather than the right DLPFC showed greater positive interaction with the visual areas V1 and V2 during the Stroop interference, but interactions of both the left and right DLPFC with the right visual area V5/MT were positively enhanced during the flanker interference. These results suggest that the flexible cognitive control is achieved by the control system's task-specific activity and its top-down interaction with domain-specific brain areas, in implementing flexible representation and modulation of control demands.
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