Evidence map›Paper›PMID 30014834›Full record

ArticleEmerging infectious diseases2018

Ancylostoma ceylanicum Hookworm in Myanmar Refugees, Thailand, 2012-2015.

Elise M O'Connell, Tarissa Mitchell, Marina Papaiakovou, Nils Pilotte, Deborah Lee, Michelle Weinberg, Potsawin Sakulrak, Dilok Tongsukh, Georgiette Oduro-Boateng, Sarah Harrison and 3 more

Abstract read
In one paragraph

Article in Emerging infectious diseases, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Zoonotic Ancylostomiasis: An Update of a Continually Neglected Zoonosis.The American journal of tropical medicine and hygiene · 2020
    Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Risk profiling and efficacy of albendazole against the hookwormsThe Lancet regional health. Western Pacific · 2021
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Elise M O'Connell
Tarissa Mitchell
Marina Papaiakovou
Nils Pilotte
Deborah Lee
Michelle Weinberg
Potsawin Sakulrak
Dilok Tongsukh
Georgiette Oduro-Boateng
Sarah Harrison
Steven A Williams
William M Stauffer
Thomas B Nutman

Funding

Clinical And Therapeutic Studies Of Human Filariasis and Related DiseasesZIAAI000439 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI NUTMAN, THOMAS · 2009 to 2025
$14.8M
Biomarkers and host-parasite interactions in neurocysticercosis and other parasitic infectionsZIAAI001234 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI NUTMAN, THOMAS · 2018 to 2025
$2.5M
6 · The paper itself

Abstract

During 2012-2015, US-bound refugees living in Myanmar-Thailand border camps (n = 1,839) were surveyed for hookworm infection and treatment response by using quantitative PCR. Samples were collected at 3 time points: after each of 2 treatments with albendazole and after resettlement in the United States. Baseline prevalence of Necator americanus hookworm was 25.4%, Ancylostoma duodenale 0%, and Ancylostoma ceylanicum (a zoonosis) 5.4%. Compared with N. americanus prevalence, A. ceylanicum hookworm prevalence peaked in younger age groups, and blood eosinophil concentrations during A. ceylanicum infection were higher than those for N. americanus infection. Female sex was associated with a lower risk for either hookworm infection. Cure rates after 1 dose of albendazole were greater for A. ceylanicum (93.3%) than N. americanus (65.9%) hookworm (p<0.001). Lower N. americanus hookworm cure rates were unrelated to β-tubulin single-nucleotide polymorphisms at codons 200 or 167. A. ceylanicum hookworm infection might be more common in humans than previously recognized.

Indexed as

RefugeesAdolescentAdultAgedAged, 80 and overAlbendazoleAncylostomaAncylostomiasisAnimalsAnthelminticsChildChild, PreschoolFecesFemaleHumansInfantAlbendazoleAnthelminticsalbendazoleAncylostomaAncylostoma ceylanicumAncylostoma duodenalebenzimidazoleBurmesecure rateeosinophilshemoglobinhookwormMyanmarNecator americanusneglected tropical diseaseparasitesrefugeesSNP167SNP200soil-transmitted helminthsThailandUnited Stateszoonosesβ-tubulin SNP

Identifiers

PMID30014834
PMCPMC6056130

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.