Evidence map›Paper›PMID 30014702›Full record

ArticleOrganic letters2018

Silicon Substitution in Oxazine Dyes Yields Near-Infrared Azasiline Fluorophores That Absorb and Emit beyond 700 nm.

Adam Choi, Stephen C Miller

Abstract read
In one paragraph

Article in Organic letters, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.8field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 26 citations in OpenAlex.

  1. Silicon Flavylium Polymethine Dyes for Shortwave Infrared Imaging.Journal of the American Chemical Society · 2026
    Article
  2. Article
  3. Ratio-based indicators for cytosolic CaProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  4. Article
  5. THQ-Xanthene: An Emerging Strategy to Create Next-Generation NIR-I/II Fluorophores.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023
    Review
  6. Article
  7. Article
  8. Article
  9. Silicon incorporation in polymethine dyes.Chemical communications (Cambridge, England) · 2020
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Adam ChoiDepartment of Biochemistry and Molecular Pharmacology , University of Massachusetts Medical School , Worcester , Massachusetts 01605 , United States.
Stephen C MillerDepartment of Biochemistry and Molecular Pharmacology , University of Massachusetts Medical School , Worcester , Massachusetts 01605 , United States.ORCID 0000-0001-7154-7757
University of Massachusetts Chan Medical School · US

Funding

Illuminating serine hydrolase activityR01DA039961 · NIDA · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI MILLER, STEPHEN C. · 2015 to 2018
$1.9M
NIDA NIH HHS R01 DA039961
6 · The paper itself

Abstract

Exchanging the bridging oxygen atom in rhodamine dyes with a dimethylsilyl group red-shifts their excitation and emission spectra, transforming orange fluorescent rhodamines into far-red Si-rhodamines. To study the effect of this substitution in other dye scaffolds, synthetic approaches to incorporate silicon into the bridging position of oxazine dyes were developed. The fluorescence of the compact azasiline dyes ASiFluor710 and ASiFluor730 is red-shifted by 57-83 nm from that of Oxazine 1.

Indexed as

CatalysisFluorescent DyesMolecular StructureOrganosilicon CompoundsOxazinesOxidation-ReductionOxygenRhodaminesSiliconSpectrometry, FluorescenceStructure-Activity RelationshipFluorescent DyesOrganosilicon CompoundsOxazinesOxygenRhodaminesSilicon

Identifiers

PMID30014702
PMCPMC6524783
OpenAlexW2883639185

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.