ArticleMagnetic resonance in medicine2019
The effects of variations in tissue microstructure from postmortem rat brain on the asymmetry of the water proton resonance.
Article in Magnetic resonance in medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Imaging white matter microstructure with gradient-echo phase imaging: Is ex vivo imaging with formalin-fixed tissue a good approximation of the in vivo brain?Magnetic resonance in medicine · 2022Article
- Multi-modal imaging of a single mouse brain over five orders of magnitude of resolution.NeuroImage · 2021Article
- Synchrotron X-ray micro-CT as a validation dataset for diffusion MRI in whole mouse brain.Magnetic resonance in medicine · 2021Article
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Abstract
purposeThis work was performed to investigate the effects of tissue microstructure from postmortem rat brain on the shape of the water proton spectrum.
methodsPerfusion-fixed, resected rat brains (N = 4) were imaged at 9.4T. 3D DTI and 3D echo-planar spectroscopic imaging (EPSI) data were acquired with 150 μm isotropic resolution. DTI data were acquired over 60 directions with b = 3000 s/mm
resultsAsymmetric broadening of the water resonance was computed for mixed populations of grey and/or white matter as determined by thresholding the fractional anisotropy. Asymmetry was shown to be differentially affected by tract orientation relative to B
conclusionPresent results demonstrate that structural variations in tissue architecture cause characteristic, reproducible changes in the water resonance shape. This suggests that water spectra are sensitive to cytoarchitectural variations in brain tissue.
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