Observational studyIndian journal of gastroenterology : official journal of the Indian Society of Gastroenterology2018
Acute kidney injury in patients with cirrhosis of liver: Clinical profile and predictors of outcome.
Observational study in Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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10 citing papers in PubMed, 19 citations in OpenAlex.
- Urinary neutrophil gelatinase-associated lipocalin: a key biomarker for differentiating acute kidney injury and predicting short-term mortality in liver cirrhosis patients.Renal failure · 2026Observational
- Predictors of Renal Replacement Therapy Requirement in Cirrhotic Patients with Acute Kidney Injury.Digestive diseases and sciences · 2025Article
- Study of prevalence, risk factors for acute kidney injury, and mortality in liver cirrhosis patients.Irish journal of medical science · 2024Article
- Clinical outcomes and prognostic factors of mortality in liver cirrhosis patients on continuous renal replacement therapy in two tertiary hospitals in Korea.Kidney research and clinical practice · 2021Article
- Acute kidney injury in hospitalized cirrhotic patients: Risk factors, type of kidney injury, and survival.JGH open : an open access journal of gastroenterology and hepatology · 2021Article
- [Comparison of clinical features between patients with acute-on-chronic liver failure and decompensated liver cirrhosis combined with acute kidney injury].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2020Article
- Reappraising the spectrum of AKI and hepatorenal syndrome in patients with cirrhosis.Nature reviews. Nephrology · 2020Review
- Predictors of Short-term Mortality in Patients of Cirrhosis of Liver Presenting as Acute Kidney Injury: An In-hospital Prospective Observational Study.Journal of clinical and experimental hepatologyArticle
- Acute Kidney Injury in Chronic Liver Disease in Northwest India: Still a Battle to Conquer.Indian journal of nephrologyArticle
- Fractional Excretion of Sodium and Urea in Differentiating Acute Kidney Injury Phenotypes in Decompensated Cirrhosis.Journal of clinical and experimental hepatologyArticle
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8 authors at 4 institutions in 1 country.
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Abstract
backgroundAcute kidney injury (AKI) is a common complication of liver cirrhosis and is associated with poor survival. We studied the clinical profile and predictors of in-hospital mortality in patients with cirrhosis of the liver with AKI.
methodsThis retrospective cohort study examined patients at a tertiary care hospital. AKI staging was done based on the new 2015 Ascites Club Criteria. Patients were grouped into three types of AKI: pre-renal azotemia (PRA), hepatorenal syndrome (HRS), and acute tubular necrosis (ATN).
resultsData of 123 patients with cirrhosis and AKI were analyzed. Most patients had AKI stage 3 (57.7%). ATN (42.3%) and HRS (43.9) were the predominant types of AKI followed by PRA (13.8%). The overall in-hospital mortality in our study was 44.7%. The mortality increased with increasing severity of AKI (p = 0.0001) and was the highest in AKI stage 3 (p = 0.001) and those who required hemodialysis (p = 0.001). There was a significant in-hospital mortality in patients with ATN and HRS in comparison to PRA (p = 0.001). On multivariate analysis, the factors predicting in-hospital mortality were AKI stage 3, and oliguria (p = 0.0001).
conclusionsAcute kidney injury in cirrhosis of liver carries high in-hospital mortality. Pre-renal AKI has a better survival compared to ATN and HRS. The higher stage of AKI at presentation and the presence of oliguria are two important predictors of in-hospital mortality.
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