Evidence map›Paper›PMID 30014235›Full record

ArticleStrahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al]2018

Prognostic factors in stereotactic body radiotherapy of lung metastases.

K J Borm, M Oechsner, K Schiller, J C Peeken, H Dapper, S Münch, L Kroll, S E Combs, M N Duma

Abstract read
PubMed Publisher
In one paragraph

Article in Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

K J BormDepartment of Radiation Oncology, Klinikum rechts der Isar, TU München, Ismaninger Straße 22, 81675, München, Germany.
M OechsnerDepartment of Radiation Oncology, Klinikum rechts der Isar, TU München, Ismaninger Straße 22, 81675, München, Germany.
K SchillerDepartment of Radiation Oncology, Klinikum rechts der Isar, TU München, Ismaninger Straße 22, 81675, München, Germany.
J C PeekenDepartment of Radiation Oncology, Klinikum rechts der Isar, TU München, Ismaninger Straße 22, 81675, München, Germany.
H DapperDepartment of Radiation Oncology, Klinikum rechts der Isar, TU München, Ismaninger Straße 22, 81675, München, Germany.
S MünchDepartment of Radiation Oncology, Klinikum rechts der Isar, TU München, Ismaninger Straße 22, 81675, München, Germany.
L KrollFakultät für Medizin, Technische Universität München, München, Germany.
S E CombsDepartment of Radiation Oncology, Klinikum rechts der Isar, TU München, Ismaninger Straße 22, 81675, München, Germany.
M N DumaDepartment of Radiation Oncology, Klinikum rechts der Isar, TU München, Ismaninger Straße 22, 81675, München, Germany. Marciana.Duma@mri.tum.de.
Klinikum rechts der Isar · DEHelmholtz Zentrum München · DETechnical University of Munich · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe aim of this study was to evaluate prognostic factors in patients with lung metastases who undergo lung stereotactic body radiotherapy (SBRT). MATERIALS AND

methodsA total of 87 patients with 129 lung metastases who underwent SBRT between November 2004 and May 2012 were enrolled in this retrospective study. The patient collective consisted of 54 men (62.1%) and 33 women (37.9%); the median age was 65 years (range 36-88). The Karnofsky performance index was ≥70% (median 90%) for all cases, but one (60%). Adverse effects were categorized using the CTCAE 4.0 classification system. Retrospective analyses regarding patients' characteristics, progression-free survival (PFS), overall survival (OS), disease-specific survival (DSS), and local tumor control rates (LTC) were performed.

resultsOn univariate and multivariate analysis OS, DSS, and PFS were significantly (p < 0.05) better for patients with ≤3 lung metastases; no extrathoracic metastases at the time of the SBRT; a gross tumor volume (GTV) <7.7 cm

conclusionThe number and pattern of metastases, and the size of the target volume are strong predictors for the outcome of patients receiving SBRT of lung tumors. FDG-PET/CT should be part of pretherapeutic staging before SBRT.

Indexed as

RadiosurgeryAdultAgedAged, 80 and overDisease-Free SurvivalFemaleFollow-Up StudiesHumansLung NeoplasmsMaleMiddle AgedNeoplasm Recurrence, LocalPrognosisRadiotherapy DosageRetreatmentRetrospective StudiesLung metastasisPET-CTPrognostic factorsSBRTStaging

Identifiers

PMID30014235
OpenAlexW2884909372

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.