Evidence map›Paper›PMID 30014224›Full record

ArticleDigestive diseases and sciences2018

Relationship Between Meal Frequency and Gastroesophageal Reflux Disease (GERD) in Iranian Adults.

Mehrbod Vakhshoori, Ammar Hassanzadeh Keshteli, Parvane Saneei, Ahmad Esmaillzadeh, Peyman Adibi

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In one paragraph

Article in Digestive diseases and sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.3field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Mehrbod VakhshooriIntegrative Functional Gastroenterology Research Center, Students' Research Committee, Isfahan University of Medical Sciences, Isfahan, Iran.
Ammar Hassanzadeh KeshteliIntegrative Functional Gastroenterology Research Center, Students' Research Committee, Isfahan University of Medical Sciences, Isfahan, Iran.
Parvane SaneeiDepartment of Community Nutrition, School of Nutrition and Food Science, Isfahan University of Medical Sciences, Isfahan, Iran. saneeip@yahoo.com.
Ahmad EsmaillzadehObesity and Eating Habits Research Center, Endocrinology and Metabolism Molecular-Cellular Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.
Peyman AdibiIntegrative Functional Gastroenterology Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
Isfahan University of Medical Sciences · IRTehran University of Medical Sciences · IRUniversity of Alberta · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe association between frequency of meals and snacks and gastroesophageal reflux disease (GERD) is less studied in Middle-Eastern countries.

aimWe aimed to determine the relationship between meal and snack frequency with GERD symptoms in a large sample of Iranian adults.

methodsIn this cross-sectional study, 4669 individuals filled out a questionnaire about their number of meals and snacks. Frequency of total meals was defined by summing up the frequency of main meals and snacks, and participants were categorized into four categories: < 3, 3-5, 6-7 and ≥ 8 meals/day. GERD was defined as having heartburn sometimes or more during the last 3 months. The severity of disease was assessed.

resultsThe prevalence of GERD in the study population was 23.7%. There was no significant association between meal or snack frequency and GERD symptoms in the whole population. However, after adjustment of all potential confounders, we found that women who consumed 1-2 or 3-5 snacks per day, compared with those who never had snacks, had a 41% (OR 0.59; 95% CI 0.42-0.84) and 51% (OR 0.49; 95% CI 0.32-0.75) reduced risk of having GERD, respectively. Women who consumed 6-7 or ≥ 8 snacks and meals per day had a 38% (OR 0.62; 95% CI 0.41-0.96) and 43% (OR 0.57; 95% CI 0.34-0.95) risk reduction for GERD compared with those who ate < 3 snacks and meals per day.

conclusionWe found no significant association between meal frequency and GERD symptoms in the whole population. Gender-specific analysis revealed inverse associations between meal and snack frequency and GERD in Iranian women. Further prospective studies are required to confirm these associations.

Indexed as

Feeding BehaviorMealsAdultCross-Sectional StudiesFemaleGastroesophageal RefluxHumansIranMaleMiddle AgedSex FactorsFeeding behaviorGastroesophageal refluxMeal frequencySnack frequency

Identifiers

PMID30014224
OpenAlexW2884045805

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.