ArticleEpilepsy & behavior case reports2018
Responsive neurostimulation for treatment of pediatric drug-resistant epilepsy.
Article in Epilepsy & behavior case reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it, 66 citations in OpenAlex.
- Responsive neurostimulation in pediatric epilepsy: a systematic review and individual patient meta-analysis supplemented by a single institution case series in 105 aggregated patients.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2024Pooled it
- A guide to neuromodulation in drug-resistant epilepsy.Epileptic disorders : international epilepsy journal with videotape · 2026Review
- The Exchange Breathing Method for Seizure Intervention: A Historical and Scientific Review of Epilepsy and Its Evolving Therapeutic Paradigms.Journal of personalized medicine · 2025Review
- Neuromorphic neuromodulation: Towards the next generation of closed-loop neurostimulation.PNAS nexus · 2024Review
- The role of neuromodulation in the management of drug-resistant epilepsy.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2024Review
- Extremely long RNS implantation effect: The extended impact of RNS electrodes on clinical and ECoG findings without the confounding effect of RNS stimulation.Epileptic disorders : international epilepsy journal with videotape · 2024Article
- Novel Surgical Approaches in Childhood Epilepsy: Laser, Brain Stimulation, and Focused Ultrasound.Advances and technical standards in neurosurgery · 2024Article
- The Utility of Responsive Neurostimulation for the Treatment of Pediatric Drug-Resistant Epilepsy.Brain sciences · 2023Review
- Beyond Tissue replacement: The Emerging role of smart implants in healthcare.Materials today. Bio · 2023Review
- A Comprehensive Review of Emerging Trends and Innovative Therapies in Epilepsy Management.Brain sciences · 2023Review
- Effect of intracranial electrical stimulation on dynamic functional connectivity in medically refractory epilepsy.Frontiers in human neuroscience · 2023Article
- Seizure freedom after laser amygdalohippocampotomy guided by bilateral responsive neurostimulation in pediatric epilepsy: illustrative case.Journal of neurosurgery. Case lessons · 2022Article
- Real-World Preliminary Experience With Responsive Neurostimulation in Pediatric Epilepsy: A Multicenter Retrospective Observational Study.Neurosurgery · 2021Observational
- Responsive Neurostimulation as a Novel Palliative Option in Epilepsy Surgery.Neurologia medico-chirurgica · 2021Review
- Prediction of Seizure Recurrence. A Note of Caution.Frontiers in neurology · 2021Article
- Case Report: Responsive Neurostimulation of the Centromedian Thalamic Nucleus for the Detection and Treatment of Seizures in Pediatric Primary Generalized Epilepsy.Frontiers in neurology · 2021Article
- Centromedian thalamic responsive neurostimulation for Lennox-Gastaut epilepsy and autism.Annals of clinical and translational neurology · 2020Article
- Epilepsy surgery in tuberous sclerosis complex (TSC): emerging techniques and redefinition of treatment goals.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2020Article
- Epilepsy surgery in children: what the radiologist needs to know.Neuroradiology · 2020Review
- Neurosurgical approaches to pediatric epilepsy: Indications, techniques, and outcomes of common surgical procedures.Seizure · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Responsive neurostimulation for epilepsy involves an implanted device that delivers direct electrical brain stimulation in response to detection of incipient seizures. Responsive neurostimulation is a safe and effective treatment for adults with drug-resistant epilepsy, but although novel treatments are critically needed for younger patients, responsive neurostimulation is currently not approved for children with drug-resistant epilepsy. Here, we report a 16-year-old patient with seizures arising from eloquent cortex, who was successfully treated with responsive neurostimulation. This case highlights the potential utility of this therapy for pediatric patients and underscores the need for larger studies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.