ArticleCurrent behavioral neuroscience reports2018
Using animal models to improve the design and application of transcranial electrical stimulation in humans.
Article in Current behavioral neuroscience reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.
- The Efficacy and Safety of Transcranial Direct Current Stimulation for Cerebellar Ataxia: a Systematic Review and Meta-Analysis.Cerebellum (London, England) · 2021Pooled it
- Polarity-dependent modulation of sensory circuits by cerebellar tDCS: local and distant effects.Scientific reports · 2026Article
- Polarity-dependent modulation of sensory circuits by cerebellar tDCS: local and distant effects.bioRxiv : the preprint server for biology · 2025Article
- Somatodendritic orientation determines tDCS-induced neuromodulation of Purkinje cell activity in awake mice.eLife · 2025Article
- Role of Hypothalamus in Acupuncture's Effects.Brain sciences · 2025Review
- Modulating excitation/inhibition balance through transcranial electrical stimulation: physiological mechanisms in animal models.Frontiers in neuroscience · 2025Review
- Preclinical insights into gamma-tACS: foundations for clinical translation in neurodegenerative diseases.Frontiers in neuroscience · 2025Review
- Transcranial alternating current stimulation (tACS) at gamma frequency: an up-and-coming tool to modify the progression of Alzheimer's Disease.Translational neurodegeneration · 2024Review
- Bioelectronic Medicine: a multidisciplinary roadmap from biophysics to precision therapies.Frontiers in integrative neuroscience · 2024Review
- Neurophysiological mechanisms of transcranial alternating current stimulation.Frontiers in neuroscience · 2023Review
- Immediate and after effects of transcranial direct-current stimulation in the mouse primary somatosensory cortex.Scientific reports · 2021Article
- Exploring new transcranial electrical stimulation strategies to modulate brain function in animal models.Current opinion in biomedical engineering · 2018Article
- Dose-response relationships in transcranial brain stimulation: Physics, physiology and mechanism.Brain stimulationReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
Abstract
purpose of reviewTranscranial electrical stimulation (tES) is a non-invasive stimulation technique used for modulating brain function in humans. To help tES reach its full therapeutic potential, it is necessary to address a number of critical gaps in our knowledge. Here, we review studies that have taken advantage of animal models to provide invaluable insight about the basic science behind tES. RECENT
findingsAnimal studies are playing a key role in elucidating the mechanisms implicated in tES, defining safety limits, validating computational models, inspiring new stimulation protocols, enhancing brain function and exploring new therapeutic applications. SUMMARY: Animal models provide a wealth of information that can facilitate the successful utilization of tES for clinical interventions in human subjects. To this end, tES experiments in animals should be carefully designed to maximize opportunities for applying discoveries to the treatment of human disease.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.