ArticleActa radiologica open2018
Extraocular muscle sampled volume in Graves' orbitopathy using 3-T fast spin-echo MRI with iterative decomposition of water and fat sequences.
Article in Acta radiologica open, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.
- A systematic review on volumetric analysis in orbital MRI.Neuroradiology · 2025Pooled it
- Quantitative analysis of orbital soft tissue for the detection of dysthyroid optic neuropathy in patients with thyroid-associated ophthalmopathy, based on three-dimensional cube fast spin-echo Flex.Quantitative imaging in medicine and surgery · 2025Article
- Analysis of extraocular muscle volumes in idiopathic hypertrophic pachymeningitis patients.PloS one · 2025Article
- Whole-orbit-based multiparametric assessment of disease activity of thyroid eye disease on Dixon MRI.International ophthalmology · 2024Article
- Clinical and imaging clues to the diagnosis and follow-up of ptosis and ophthalmoparesis.Journal of cachexia, sarcopenia and muscle · 2022Review
- Multiparametric quantitative MRI for the evaluation of dysthyroid optic neuropathy.European radiology · 2022Article
- Dixon-T2WI magnetic resonance imaging at 3 tesla outperforms conventional imaging for thyroid eye disease.European radiology · 2021Article
- Evaluation of bone marrow infiltration in multiple myeloma using whole-body diffusion-weighted imaging and T1-weighted water-fat separation Dixon.Quantitative imaging in medicine and surgery · 2021Article
- The feasibility of quantitative MRI of extra-ocular muscles in myasthenia gravis and Graves' orbitopathy.NMR in biomedicine · 2021Article
- Cross-Sectional Area Measurement Techniques of Soft Tissue: A Literature Review.Orthopaedic surgery · 2020Review
- Neuroradiological and clinical features in ophthalmoplegia.Neuroradiology · 2019Review
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCurrent magnetic resonance imaging (MRI) techniques for measuring extraocular muscle (EOM) volume enlargement are not ideally suited for routine follow-up of Graves' ophthalmopathy (GO) because the difficulty of segmenting the muscles at the tendon insertion complicates and lengthens the study protocol. PURPOSE: To measure the EOM sampled volume (SV) and assess its correlation with proptosis. MATERIAL AND
methodsA total of 37 patients with newly diagnosed GO underwent 3-T MRI scanning with iterative decomposition of water and fat (IDEAL) sequences with and without contrast enhancement. In each patient, the three largest contiguous coronal cross-sectional areas (CSA) on the EOM slices were segmented using a polygon selection tool and then summed to compute the EOM-SV. Proptosis was evaluated with the Hertel index (HI). The relationships between the HI value and EOM-SV and between HI and EOM-CSA were compared and assessed with Pearson's correlation coefficient and the univariate regression coefficient. Inter-observer and intra-observer variability were calculated.
resultsHI showed a stronger correlation with EOM-SV (
conclusionIDEAL sequences allow for the measurement EOM-SV both on non-contrast and contrast-enhanced scans. EOM-SV predicts proptosis more accurately than does EOM-CSA. The measurement of EOM-SV is practical and reproducible. EOM-SV changes of 3.5-8.3% can be assumed to reflect true volume changes.
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