ArticleGastroenterology and hepatology from bed to bench2018
Prevalence of celiac disease serological markers in a cohort of Italian rheumatological patients.
Article in Gastroenterology and hepatology from bed to bench, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.
- Prevalence of coeliac disease in patients with systemic lupus erythematosus: a systematic review and meta-analysis.Lupus science & medicine · 2024Pooled it
- Systemic Lupus Erythematosus and the Risk of Coeliac Disease: Substantial Discrepancies Among Studies Highlight a Significant Research Gap.Mediterranean journal of rheumatology · 2026Review
- Prevalence and Significance of the Presence of Anti-transglutaminase and Anti-endomysium Antibodies in Patients with Early Inflammatory Joint Disease.Rheumatology and therapy · 2025Article
- Commentary: Prevalence and incidence of celiac disease in patients with rheumatoid arthritis: a case-control study based on the RECORD cohort.Frontiers in medicine · 2025Article
- Commentary: Prevalence and incidence of celiac disease in patients with rheumatoid arthritis: a case-control study based on the RECORD cohort.Frontiers in medicine · 2025Article
- Gluten and Wheat in Women's Health: Beyond the Gut.Nutrients · 2024Review
- Prevalence and incidence of celiac disease in patients with rheumatoid arthritis: a case-control study based on the RECORD cohort.Frontiers in medicine · 2024Article
- Cutaneous Disorders Masking Celiac Disease: Case Report and Mini Review with Proposal for a Practical Clinical Approach.Nutrients · 2023Review
- Autoimmune polyendocrine syndromes associated with autoimmune rheumatic diseases.Reumatologia · 2023Review
- Frequency of serological markers of rheumatoid arthritis in adult patients with active celiac disease.Journal of clinical laboratory analysis · 2022Article
- Causal association between rheumatoid arthritis and celiac disease: A bidirectional two-sample mendelian randomization study.Frontiers in genetics · 2022Article
- Celiac disease and Sjögren's syndrome: A case report and review of literature.World journal of clinical cases · 2020Article
- The Value of Screening for Celiac Disease in Systemic Lupus Erythematosus: A Single Experience of a Tertiary Medical Center.Rheumatology and therapy · 2020Article
- Effect of Gluten-Free Diet on Gut Microbiota Composition in Patients with Celiac Disease and Non-Celiac Gluten/Wheat Sensitivity.Nutrients · 2020Review
- Celiac disease: a comprehensive current review.BMC medicine · 2019Review
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo assess the prevalence of celiac disease (CD) serological markers in a cohort of patients referred to an Italian rheumatological outpatient clinic.
backgroundCurrent guidelines do not suggest CD screening in patients with rheumatological diseases and these subjects are not considered to be at high risk for CD.
methodsA total of 230 sera of rheumatological patients referred to the Division of Internal Medicine at the Department of Medical and Surgical Sciences between January 2005 and December 2013 were screened for CD by testing IgA antitransglutaminase (TTG IgA), IgG deamidated gliadin peptides (DGP IgG) and IgA antiendomysium (EMA) antibodies. Of the 230 patients tested, 67 had a diagnosis of rheumatoid arthritis (RA), 52 Sjögren's syndrome (SjS), 42 systemic sclerosis (SCL), 35 systemic lupus erythematosus (SLE), 15 mixed connective tissue disease, 11 polymyositis and 10 dermatomyositis.
resultsTTG IgA antibodies were identified in 7/230 cases (3%), 3 in SjS (3/42 - 5.8%), 2 in SCL (2/42 - 4.8%), 1 in RA (1/67 - 1.5%) and 1 in SLE sera (1/35 - 2.8%). All the seven sera were also positive for DGP IgG and EMA IgA. DGP IgG were the most frequent antibody detected, being found in 16 (7%) sera.
conclusionThis study identified a high prevalence of CD antibodies in adult patients referred to a rheumatology outpatient clinic. These results highlight the importance of CD screening in subjects presenting with rheumatological features.
Indexed as
Identifiers
30013749PMC6040033W2887635479What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.