Evidence map›Paper›PMID 30013719›Full record

ArticleOxidative medicine and cellular longevity2018

Mangiferin and Morin Attenuate Oxidative Stress, Mitochondrial Dysfunction, and Neurocytotoxicity, Induced by Amyloid Beta Oligomers.

Elena Alberdi, María Victoria Sánchez-Gómez, Asier Ruiz, Fabio Cavaliere, Carolina Ortiz-Sanz, Tania Quintela-López, Estibaliz Capetillo-Zarate, Santiago Solé-Domènech, Carlos Matute

Registry-linked trialOpen access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07126717 (Confirmatory Study on the Acute Effects of Zynamite® S on Cognitive Function and Mood in University Students), which is not on this map. Cited by 44 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed, 1 pooled it
14.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07126717 nacompletednot on this mapstarted 2025, after this paper: background citation

Confirmatory Study on the Acute Effects of Zynamite® S on Cognitive Function and Mood in University Students: a Randomized, Double-blind, Placebo-controlled Crossover Study

TypeinterventionalSponsorNektium Pharma SLRan2025 to 2025Enrolled88ConditionsCognitive Performance, MoodArmsPlacebo, Zynamite® S
3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 1 synthesis or guideline pooled it, 94 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Acute Supplementation of Soluble Mango Leaf Extract (ZynamitePharmaceuticals (Basel, Switzerland) · 2025
    Article
  8. Article
  9. Article
  10. From Nature to Nanotechnology: The Bioactivities of Mangiferin Explored.Nanotechnology, science and applications · 2025
    Review
  11. Review
  12. Review
  13. Article
  14. Review
  15. Review
  16. Review
  17. International journal of molecular sciences · 2023
    Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Elena AlberdiDepartamento de Neurociencias, Universidad del País Vasco (UPV/EHU), 48940 Leioa, Spain.ORCID 0000-0002-8000-142X
María Victoria Sánchez-GómezDepartamento de Neurociencias, Universidad del País Vasco (UPV/EHU), 48940 Leioa, Spain.
Asier RuizDepartamento de Neurociencias, Universidad del País Vasco (UPV/EHU), 48940 Leioa, Spain.
Fabio CavaliereDepartamento de Neurociencias, Universidad del País Vasco (UPV/EHU), 48940 Leioa, Spain.
Carolina Ortiz-SanzDepartamento de Neurociencias, Universidad del País Vasco (UPV/EHU), 48940 Leioa, Spain.
Tania Quintela-LópezDepartamento de Neurociencias, Universidad del País Vasco (UPV/EHU), 48940 Leioa, Spain.
Estibaliz Capetillo-ZarateDepartamento de Neurociencias, Universidad del País Vasco (UPV/EHU), 48940 Leioa, Spain.
Santiago Solé-DomènechDepartment of Biochemistry, Weill Cornell Medical College, 1300 York Avenue, New York, NY 10065, USA.
Carlos MatuteDepartamento de Neurociencias, Universidad del País Vasco (UPV/EHU), 48940 Leioa, Spain.ORCID 0000-0001-8672-711X
University of the Basque Country · ESCornell University · USIkerbasque · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Amyloid beta- (A

Indexed as

Alzheimer DiseaseAmyloid beta-PeptidesAnimalsAntioxidantsApoptosisCalciumCell DeathCells, CulturedCell SurvivalCytosolFlavonesFlavonoidsImmunohistochemistryMembrane Potential, MitochondrialMitochondriaNeuronsAmyloid beta-PeptidesAntioxidantsCalciumFlavonesFlavonoidsmangiferinmorinNeuroprotective AgentsReactive Oxygen SpeciesXanthones

Identifiers

PMID30013719
PMCPMC6022276
OpenAlexW2808271437

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.