Evidence map›Paper›PMID 30013718›Full record

ArticleOxidative medicine and cellular longevity2018

Persistent Increased Frequency of Genomic Instability in Women Diagnosed with Breast Cancer: Before, during, and after Treatments.

Márcia Fernanda Correia Jardim Paz, André Luiz Pinho Sobral, Jaqueline Nascimento Picada, Ivana Grivicich, Antonio Luiz Gomes Júnior, Ana Maria Oliveira Ferreira da Mata, Marcus Vinícius Oliveira Barros de Alencar, Rodrigo Mendes de Carvalho, Kátia da Conceição Machado, Muhammad Torequl Islam and 2 more

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Genetic variability of oxidative stress and DNA repair genes associated with pre-treatment cancer-related fatigue in women with breast cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023
    Article
  2. The radioprotective effect of N-acetylcysteine against x-radiation-induced renal injury in rats.Environmental science and pollution research international · 2019
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

Márcia Fernanda Correia Jardim PazLaboratory of Genetic Toxicology, PPGBioSaúde and PPGGTA, Lutheran University of Brazil (ULBRA), Av. Farroupilha 8001, Prédio 22, Sala 22 (4° Andar), 92425-900 Canoas, RS, Brazil.ORCID 0000-0002-6086-6469
André Luiz Pinho SobralUniversity Hospital of Piauí, Av. Universitária, S/N, Ininga, 64049-550 Teresina, PI, Brazil.
Jaqueline Nascimento PicadaLaboratory of Genetic Toxicology, PPGBioSaúde and PPGGTA, Lutheran University of Brazil (ULBRA), Av. Farroupilha 8001, Prédio 22, Sala 22 (4° Andar), 92425-900 Canoas, RS, Brazil.ORCID 0000-0003-2360-1557
Ivana GrivicichLaboratory of Cancer Biology, PPGBioSaúde and PPGGTA, Lutheran University of Brazil (ULBRA), Av. Farroupilha 8001, Prédio 22, Sala 22 (4° Andar), 92425-900 Canoas, RS, Brazil.
Antonio Luiz Gomes JúniorLaboratory of Genetic Toxicology, PPGCF, Federal University of Piauí, Av. Universitária S/N, Ininga, 64049-550 Teresina, PI, Brazil.
Ana Maria Oliveira Ferreira da MataLaboratory of Genetic Toxicology, PPGCF, Federal University of Piauí, Av. Universitária S/N, Ininga, 64049-550 Teresina, PI, Brazil.
Marcus Vinícius Oliveira Barros de AlencarLaboratory of Genetic Toxicology, PPGCF, Federal University of Piauí, Av. Universitária S/N, Ininga, 64049-550 Teresina, PI, Brazil.ORCID 0000-0002-4048-1457
Rodrigo Mendes de CarvalhoCentral Laboratory of Public Health of Piauí, Rua Dezenove de Novembro 1945, Bairro Primavera, 64002-570 Teresina, PI, Brazil.
Kátia da Conceição MachadoLaboratory of Genetic Toxicology, PPGCF, Federal University of Piauí, Av. Universitária S/N, Ininga, 64049-550 Teresina, PI, Brazil.
Muhammad Torequl IslamDepartment for Management of Science and Technology Development, Ton Duc Thang University, Ho Chi Minh City 700000, Vietnam.ORCID 0000-0003-0034-8202
Ana Amélia de Carvalho Melo CavalcanteLaboratory of Genetic Toxicology, PPGCF, Federal University of Piauí, Av. Universitária S/N, Ininga, 64049-550 Teresina, PI, Brazil.
Juliana da SilvaLaboratory of Genetic Toxicology, PPGBioSaúde and PPGGTA, Lutheran University of Brazil (ULBRA), Av. Farroupilha 8001, Prédio 22, Sala 22 (4° Andar), 92425-900 Canoas, RS, Brazil.ORCID 0000-0002-1089-6766
Universidade Federal do Piauí · BRUniversidade Luterana do Brasil · BRTon Duc Thang University · VNUniversidade Estadual do Piauí · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to evaluate DNA damage in patients with breast cancer before treatment (background) and after chemotherapy (QT) and radiotherapy (RT) treatment using the Comet assay in peripheral blood and the micronucleus test in buccal cells. We also evaluated repair of DNA damage after the end of RT, as well as the response of patient's cells before treatment with an oxidizing agent (H

Indexed as

AdultBreast NeoplasmsCells, CulturedComet AssayDNA DamageFemaleHumansHydrogen PeroxideMicronucleus TestsMiddle AgedOxidative StressHydrogen Peroxide

Identifiers

PMID30013718
PMCPMC6022262
OpenAlexW2808655054

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.