Evidence map›Paper›PMID 30013640›Full record

ArticleOncology letters2018

Effects of miRNA-130a on the proliferation and apoptosis of glioma cell lines.

Ke Lu, Hechun Shen, Sheng Zhu, Shuiqing Bi, Shengtian Wu

Abstract read
In one paragraph

Article in Oncology letters, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. MiR-3150b-3p inhibits the progression of colorectal cancer cells via targeting GOLPH3.Journal of investigative medicine : the official publication of the American Federation for Clinical Research · 2020
    Article
  6. Article
  7. microRNA-1471 suppresses glioma cell growth and invasion by repressing metadherin expression.International journal of clinical and experimental pathology · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ke LuDepartment of Neurosurgery, The Second Nanning People's Hospital, Nanning, Guangxi 530031, P.R. China.
Hechun ShenDepartment of Neurosurgery, The Second Nanning People's Hospital, Nanning, Guangxi 530031, P.R. China.
Sheng ZhuDepartment of Neurosurgery, The Second Nanning People's Hospital, Nanning, Guangxi 530031, P.R. China.
Shuiqing BiDepartment of Neurosurgery, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi 530021, P.R. China.
Shengtian WuDepartment of Neurosurgery, The Second Nanning People's Hospital, Nanning, Guangxi 530031, P.R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Regulatory ability of micro-ribose nucleic acid-130a (miRNA-130a) in the proliferation and invasive growth of human brain glioma cells and its mechanism were investigated. RT-qPCR was used to analyze expression of miRNA-130a in U-87MG glioma specimens; lipidosome was used to mediate miRNA-130a mimic transfecting glioma cells and the expression of miRNA-130a was detected by using RT-qPCR after transfection; methyl thiazolyl tetrazolium (MTT) assay and flow cytometry (FCM) were adopted to evaluate the changes in biological characteristics of cell growth and proliferation; the migration and invasion abilities of tumor cells were measured through scratch assay and Transwell

Indexed as

cell linegliomamiRNA-130proliferation and apoptosistransfection

Identifiers

PMID30013640
PMCPMC6036606

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.