Evidence map›Paper›PMID 30013611›Full record

ArticleUltrasound (Leeds, England)2018

A retrospective review of the role of B-mode and color Doppler ultrasonography in the investigation of primary hyperparathyroidism: Features that differentiate benign from malignant lesions.

Cheng Fang, Eleni Konstantatou, Nicola J Mulholland, Serena Baroncini, Mohammad A Husainy, Klaus-Martin Schulte, Paul S Sidhu

Open access · greenAbstract read
In one paragraph

Article in Ultrasound (Leeds, England), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Cheng FangDepartment of Radiology, King's College Hospital NHS Foundation Trust London, London, UK.ORCID 0000-0001-9649-8904
Eleni KonstantatouDepartment of Radiology, King's College Hospital NHS Foundation Trust London, London, UK.
Nicola J MulhollandDepartment of Radiology, King's College Hospital NHS Foundation Trust London, London, UK.
Serena BaronciniDepartment of Radiology, King's College Hospital NHS Foundation Trust London, London, UK.
Mohammad A HusainyDepartment of Radiology, King's College Hospital NHS Foundation Trust London, London, UK.
Klaus-Martin SchulteDepartment of Radiology, King's College Hospital NHS Foundation Trust London, London, UK.
Paul S SidhuDepartment of Radiology, King's College Hospital NHS Foundation Trust London, London, UK.
King's College Hospital NHS Foundation Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo identify the variant features encountered in parathyroid abnormalities and document those suggesting malignant change. MATERIALS AND

methodsData were collected from a cohort of patients who underwent investigation for primary hyperparathyroidism over a 10-year period. Ultrasonographic features: shape, presence of calcification, cystic changes, heterogeneous echogenicity, vascularity, capsular thickening, local invasion, and vascularity were reviewed retrospectively and were used to correlate with final histological findings.

resultsOne hundred forty-seven patients with histology and concurrent ultrasonographic scans were reviewed, and divided into benign parathyroid lesions (nodular hyperplasia (

conclusionUltrasonographic features such as irregular shape, heterogeneous echogenicity, cystic change, and vascularity are nondiscriminatory features between benign or malignant lesions. Large lesion size together with the presence of calcification, capsular thickening, or infiltrative margin strongly raises the suspicion of a malignant parathyroid lesion, and management should be altered.

Indexed as

Color Dopplerparathyroid adenomaparathyroid carcinomaprimary hyperparathyroidismsonographyultrasound

Identifiers

PMID30013611
PMCPMC6042299
OpenAlexW2791412536

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.