Evidence map›Paper›PMID 30013598›Full record

ArticleObstetrics and gynecology international2018

Changes in Uterine Cancer Incidence Rates in Egypt.

Saad Alshahrani, Amr S Soliman, Ahmed Hablas, Mohamed Ramadan, Jane L Meza, Steven Remmenga, Ibrahim A Seifeldein, Robert M Chamberlain

Registry-linked trialAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Obstetrics and gynecology international, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05056259 (Usefulness of 18F-FDG PET/CT in the Initial Staging and Surveillance of Endometrial Cancer Patients), which is not on this map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05056259 unknown statusnot on this mapstarted 2022, after this paper: background citation

Usefulness of 18F-FDG PET/CT in the Initial Staging and Surveillance of Endometrial Cancer Patients

TypeobservationalSponsorAssiut UniversityRan2022 to 2023Enrolled42ConditionsEndometrial CancerArms18F-FDG PET/CT
3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Observational
  3. [Body mass index and triponderal index in abnormal uterine bleed].Revista medica del Instituto Mexicano del Seguro Social · 2023
    Observational
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Saad AlshahraniDepartment of Epidemiology, College of Public Health, University of Nebraska Medical Center, Omaha, NE, USA.ORCID 0000-0002-7096-1072
Amr S SolimanDepartment of Community Health and Social Medicine, School of Medicine, City University of New York, New York, NY, USA.ORCID 0000-0003-2284-360X
Ahmed HablasGharbiah Cancer Society and Gharbiah Cancer Registry, Tanta 31512, Egypt.ORCID 0000-0001-8898-5200
Mohamed RamadanGharbiah Cancer Society and Gharbiah Cancer Registry, Tanta 31512, Egypt.
Jane L MezaDepartment of Biostatistics, College of Public Health, University of Nebraska Medical Center, Omaha, NE, USA.
Steven RemmengaDepartment of Obstetrics and Gynecology, University of Nebraska Medical Center, Omaha, NE, USA.
Ibrahim A SeifeldeinGharbiah Cancer Society and Gharbiah Cancer Registry, Tanta 31512, Egypt.
Robert M ChamberlainDepartment of Community Health and Social Medicine, School of Medicine, City University of New York, New York, NY, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundUterine cancer is one of the top-ranking cancers in women with wide international variations in incidence rates. Developed countries have higher incidence rates than the developing countries. Egypt has significantly lower incidence of uterine cancer than other countries in the Middle East. This study aimed at verifying the incidence rate of uterine cancer and characterizing the demographic and clinical profiles of patients residing in the Gharbiah province in the Nile delta region of Egypt.

methodsData from 660 uterine cancer patients diagnosed during the period of 1999 to 2010 were abstracted from the Gharbiah Cancer Registry, the only population-based registry in Egypt. The data included age, marital status, number of children, residence, smoking, occupation, date and basis of diagnosis, tumor topography, morphology, stage and grade, and treatment. Crude rate, age-standardized rate (ASR), and age-specific rate were calculated and associated with demographic and clinical characteristics of patients.

resultsThe study confirmed the low ASR of uterine cancer in Egypt, (4.1 per 100,000 (95% CI: 3.8-4.4)). The incidence rate increased significantly over the 12-year period. The crude rate (CR) was 1.95, 95% CI (1.64-2.25) in 1999-2002; 2.9, 95% CI (2.5-3.2) in 2003-2006; and 3.5, 95% CI (3.1-3.9) in 2007-2010. The rate ratio was 1.5, 95% CI (1.2-1.8) in 2003-2006 and 1.8, 95% CI (1.5-2.2) in 2007-2010 compared to 1999-2002. The majority of patients (83%) were postmenopausal with the highest age-specific rate in the 60-69-year age group (22.07 per 100,000 (95% CI: 19.3-25.2). The majority of patients were diagnosed at early stages (60% localized and 5% regional), had adenocarcinoma (68%), and resided in urban areas (54%).

conclusionsThe study confirmed the low incidence rate of uterine cancer in the Gharbiah province of Egypt and significant increase in incidence in recent years. Future studies should focus on verifying the possible effect of hysterectomy on lowering the incidence, the factors related to the changes in rates between rural and urban areas, and the possible impact of nutritional and epidemiologic transitions on the increasing rates.

Identifiers

PMID30013598
PMCPMC6022259

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