Evidence map›Paper›PMID 30013482›Full record

ArticleFrontiers in physiology2018

Physical Activity, Immune System, and the Microbiome in Cardiovascular Disease.

Dawn M Fernandez, Jose C Clemente, Chiara Giannarelli

Abstract read
In one paragraph

Article in Frontiers in physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Observational
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Ten things to know about ten cardiovascular disease risk factors - 2022.American journal of preventive cardiology · 2022
    Review
  10. Review
  11. Ten things to know about ten cardiovascular disease risk factors.American journal of preventive cardiology · 2021
    Review
  12. Article
  13. Review
  14. Article
  15. Article
  16. Review
  17. Cardiovascular Effects and Benefits of Exercise.Frontiers in cardiovascular medicine · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Dawn M FernandezDepartment of Medicine, Cardiovascular Research Center, Icahn School of Medicine at Mount Sinai, New York, NY, United States.
Jose C ClementeDepartment of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, United States.
Chiara GiannarelliDepartment of Medicine, Cardiovascular Research Center, Icahn School of Medicine at Mount Sinai, New York, NY, United States.

Funding

TRAINING PROGRAM IN MOLECULAR AND CELLULAR CARDIOLOGYT32HL007824 · NHLBI · MOUNT SINAI SCHOOL OF MEDICINE OF NYU · PI GELB, BRUCE D · 1995 to 2022
$8.6M
Hippocampal Inflammation as a Pathophysiology for PsychosisR01MH110418 · NIMH · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI MALASPINA, DOLORES · 2017 to 2021
$3.8M
Role of alternatively spliced Tissue Factor in atherosclerosisK23HL111339 · NHLBI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI GIANNARELLI, CHIARA · 2013 to 2017
$782k
Network-driven drug repurposing approaches to treat coronary artery diseaseR21TR001739 · NCATS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI BJORKEGREN, JOHAN M, GIANNARELLI, CHIARA · 2016 to 2017
$678k
Single-cell-driven drug repositioning approaches to target inflammation in atherosclerosisUH2TR002067 · NCATS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI GIANNARELLI, CHIARA · 2017 to 2018
$678k
Dissecting the cellular and molecular immune interactions in human atherosclerosisR03HL135289 · NHLBI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI GIANNARELLI, CHIARA · 2016 to 2017
$170k
NCATS NIH HHS R21 TR001739NCATS NIH HHS UH2 TR002067NHLBI NIH HHS K23 HL111339NHLBI NIH HHS R03 HL135289NHLBI NIH HHS T32 HL007824NIMH NIH HHS R01 MH110418
6 · The paper itself

Abstract

Cardiovascular health is a primary research focus, as it is a leading contributor to mortality and morbidity worldwide, and is prohibitively costly for healthcare. Atherosclerosis, the main driver of cardiovascular disease, is now recognized as an inflammatory disorder. Physical activity (PA) may have a more important role in cardiovascular health than previously expected. This review overviews the contribution of PA to cardiovascular health, the inflammatory role of atherosclerosis, and the emerging evidence of the microbiome as a regulator of inflammation.

Indexed as

atherosclerosiscardiovascular diseaseinflammationmicrobiomephysical activity

Identifiers

PMID30013482
PMCPMC6036301

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.