ReviewInternational journal of medical sciences2018
A Review on the Effects of Bisphenol A and Its Derivatives on Skeletal Health.
Review in International journal of medical sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed, 1 synthesis or guideline pooled it, 67 citations in OpenAlex.
- Pooled it
- Curcumin Attenuates Bisphenol F-Induced Osteoporosis and Osteogenic Dysfunction via PI3K/AKT Pathway Activation.Nutrients · 2026Article
- Article
- Investigating the mechanisms by which bisphenol A affects osteoarthritis through a novel network toxicology framework and experimental validation.BMC pharmacology & toxicology · 2026Article
- The cannabinoid receptor 2 is an in vivo receptor of bisphenol A during bone formation.Journal of hazardous materials · 2026Article
- Use of Amalgam and Composite Restorations Among 12-Year-Old Children in Israel: A Retrospective Study.Biomimetics (Basel, Switzerland) · 2025Article
- Molecular networking derived from untargeted LC-MS/MS analysis to discover inhibitors of RANKL-induced osteoclastogenesis from Egyptian marine sponge-associated fungi.Scientific reports · 2025Article
- Identification of lactylation-related biomarkers in osteoporosis from transcriptome and single-cell data.Frontiers in endocrinology · 2025Article
- Prenatal Exposure to a Human Relevant Mixture of Endocrine-Disrupting Chemicals Affects Mandibular Development in Mice.International journal of molecular sciences · 2024Article
- Article
- Molecular mechanisms of environmental pollutant-induced cartilage damage: from developmental disorders to osteoarthritis.Archives of toxicology · 2024Review
- Effects of Endocrine-Disrupting Chemicals on Bone Health.Endocrinology and metabolism (Seoul, Korea) · 2024Review
- Bisphenol A-What Do We Know? A Global or Local Approach at the Public Health Risk Level.International journal of molecular sciences · 2024Review
- A Novel Magnetic β-Cyclodextrin-Modified Graphene Oxide and Chitosan Composite as an Adsorbent for Trace Extraction of Four Bisphenol Pollutants from Environmental Water Samples and Food Samples.Molecules (Basel, Switzerland) · 2024Article
- Prenatal Phenol and Paraben Exposures and Adverse Birth Outcomes: A Prospective Analysis of U.S. Births.Environment international · 2024Article
- Effects of Endocrine Disrupting Chemicals (EDCs) on Skeletal System Development: A Review.Cureus · 2023Review
- Effects of bisphenol F, bisphenol S, and bisphenol AF on cultured human osteoblasts.Archives of toxicology · 2023Article
- Current Evidence on Bisphenol A Exposure and the Molecular Mechanism Involved in Related Pathological Conditions.Pharmaceutics · 2023Review
- Associations of maternal gestational urinary environmental phenols concentrations with bone mineral density among 12-year-old children in the HOME Study.International journal of hygiene and environmental health · 2023Article
- Modulation of Osteogenic Gene Expression by Human Osteoblasts Cultured in the Presence of Bisphenols BPF, BPS, or BPAF.International journal of molecular sciences · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Bisphenol A (BPA) is an endocrine disruptor which can bind to the oestrogen receptor. It also possesses oestrogenic, antiandrogenic, inflammatory and oxidative properties. Since bone responds to changes in sex hormones, inflammatory and oxidative status, BPA exposure could influence bone health in humans. This review aimed to summarize the current evidence on the relationship between BPA and bone health derived from cellular, animal and human studies. Exposure to BPA (0.5-12.5 µM) decreased the proliferation of osteoblast and osteoclast precursor cells and induce their apoptosis. Bisphenol AF (10 nM) enhanced transforming growth factor beta signalling but bisphenol S (10 nM) inhibited Wnt signalling involved in osteoblast differentiation
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.