Evidence map›Paper›PMID 30013443›Full record

ArticleInternational journal of medical sciences2018

Trehalose inhibits H

Zhijie Gao, Helei Wang, Bo Zhang, Xuemei Wu, Yanfeng Zhang, Pengfei Ge, Guangfan Chi, Jianmin Liang

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in International journal of medical sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 37 citations in OpenAlex.

  1. Article
  2. A brain-derived tau oligomer polymorph is associated with cognitive resilience to Alzheimer's disease.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Article
  3. Article
  4. Review
  5. Metabolomic Analysis of Trehalose Alleviating Oxidative Stress in Myoblasts.International journal of molecular sciences · 2023
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Trehalose Protects the Probiotic YeastJournal of microbiology and biotechnology · 2020
    Article
  14. Article
  15. Neuroprotective Effects ofAntioxidants (Basel, Switzerland) · 2019
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Zhijie GaoDepartment of Neurosurgery, First hospital of Jilin University, Changchun 130021, China.
Helei WangDepartment of Gastrointestinal Surgery, First hospital of Jilin University, Changchun 130021, China.
Bo ZhangDepartment of Pediatric Neurology, First hospital of Jilin University, Changchun 130021, China.
Xuemei WuDepartment of Pediatric Neurology, First hospital of Jilin University, Changchun 130021, China.
Yanfeng ZhangDepartment of Pediatric Neurology, First hospital of Jilin University, Changchun 130021, China.
Pengfei GeDepartment of Neurosurgery, First hospital of Jilin University, Changchun 130021, China.
Guangfan ChiKey Laboratory of Pathobiology, Ministry of Education, Jilin University, Changchun 130021, China.
Jianmin LiangDepartment of Pediatric Neurology, First hospital of Jilin University, Changchun 130021, China.
Jilin University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Autophagy is a catabolic process to maintain intracellular homeostasis via removal of cytoplasmic macromolecules and damaged cellular organelles through lysosome-mediated degradation. Trehalose is often regarded as an autophagy inducer, but we reported previously that it could prevent ischemic insults-induced autophagic death in neurons. Thus, we further investigated in this study whether trehalose could protect human dopaminergic SH-SY5Y cells against H

Indexed as

ApoptosisAutophagyEndoplasmic Reticulum StressAnimalsCell Line, TumorHumansHydrogen PeroxideNeuroblastomaReactive Oxygen SpeciesTrehaloseHydrogen PeroxideReactive Oxygen SpeciesTrehaloseAMPKAutophagyEndoplasmic reticulum stressOxidative stressTrehalose

Identifiers

PMID30013443
PMCPMC6036158
OpenAlexW2807839371

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.