Evidence map›Paper›PMID 30013433›Full record

ArticleReproductive medicine and biology2018

Identifying a possible factor for the increased newborn size in singleton pregnancies after assisted reproductive technology using cryopreserved embryos, in comparison with fresh embryos.

Rena Ishii, Akiko Shoda, Michiyo Kubo, Satiko Okazaki, Minori Suzuki, Riho Okawa, Megumi Enomoto, Manami Shitanaka, Yoko Fujita, Kazuki Nakao and 4 more

Open access · goldAbstract read
In one paragraph

Article in Reproductive medicine and biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Rena IshiiWomen's Clinic Oizumi Gakuen Lenia Medical Corporation Tokyo Japan.ORCID 0000-0002-4067-1066
Akiko ShodaWomen's Clinic Oizumi Gakuen Lenia Medical Corporation Tokyo Japan.
Michiyo KuboWomen's Clinic Oizumi Gakuen Lenia Medical Corporation Tokyo Japan.
Satiko OkazakiWomen's Clinic Oizumi Gakuen Lenia Medical Corporation Tokyo Japan.
Minori SuzukiWomen's Clinic Oizumi Gakuen Lenia Medical Corporation Tokyo Japan.
Riho OkawaWomen's Clinic Oizumi Gakuen Lenia Medical Corporation Tokyo Japan.
Megumi EnomotoWomen's Clinic Oizumi Gakuen Lenia Medical Corporation Tokyo Japan.
Manami ShitanakaWomen's Clinic Oizumi Gakuen Lenia Medical Corporation Tokyo Japan.
Yoko FujitaWomen's Clinic Oizumi Gakuen Lenia Medical Corporation Tokyo Japan.
Kazuki NakaoWomen's Clinic Oizumi Gakuen Lenia Medical Corporation Tokyo Japan.
Nobutaka ShimadaArtemis Women's Hospital Lenia Medical Corporation Tokyo Japan.
Michiharu HorikawaWomen's Clinic Oizumi Gakuen Lenia Medical Corporation Tokyo Japan.
Hiroaki NegishiWomen's Clinic Oizumi Gakuen Lenia Medical Corporation Tokyo Japan.
Yuji TaketaniWomen's Clinic Oizumi Gakuen Lenia Medical Corporation Tokyo Japan.
Tokyo Women's Medical University · JPTokyo Women's Medical University Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo determine whether the cycle regimens that are used for endometrial preparation are associated with the birthweight (BW) after assisted reproductive technology (ART) using frozen-thawed embryo transfer (FET).

methodsThe BW of singletons who were born by ART using FET was compared retrospectively, according to whether a FET was conducted in a hormone replacement therapy cycle (HRT, n

resultsThere were no significant differences in the age of the mothers, percentage of primiparas, gestational periods, Body Mass Index, and sex ratio between the HRT and OVL cycles. The average BW from HRT was significantly greater than that of OVL. The BW from HRT was also greater, compared with NAT, while statistical significance was not achieved between OVL and NAT. The putative factors affecting the BW, such as ovarian stimulation protocols, endometrial thickness, and the stage and quality of embryos, could not explain the difference in the BW between the HRT and OVL cycles.

conclusionAn increased BW from ART using FET seems to be ascribable to conditions of the endometrium, but not cryopreservation procedures per se, which might provide a mechanistic framework for understanding heavier neonates who are born by FET.

Indexed as

assisted reproductive technologybirthweightendometrial preparationfrozen embryohormone replacement therapy

Identifiers

PMID30013433
PMCPMC6046533
OpenAlexW2800993335

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.