Evidence map›Paper›PMID 30013399›Full record

ArticleCancer management and research2018

Recurrence risk after preoperative biopsy in patients with resected early-stage non-small-cell lung cancer: a retrospective study.

Chengping Hu, Juan Jiang, Yuanyuan Li, Chunfang Zhang, Weixing Zhang, Haihe Jiang, Yang Gao, Wei Zhuang, Kaibo Lei, Yong Tang and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancer management and research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 2 pooled it
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 2 syntheses or guidelines pooled it, 10 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Chengping HuDepartment of Respiratory and Critical Care Medicine, National Key Clinical Specialty, Xiangya Hospital, Central South University, Changsha, China, leeround@csu.edu.cn.
Juan JiangDepartment of Respiratory and Critical Care Medicine, National Key Clinical Specialty, Xiangya Hospital, Central South University, Changsha, China, leeround@csu.edu.cn.
Yuanyuan LiDepartment of Respiratory and Critical Care Medicine, National Key Clinical Specialty, Xiangya Hospital, Central South University, Changsha, China, leeround@csu.edu.cn.
Chunfang ZhangDepartment of Thoracic Surgery, Xiangya Hospital, Central South University, Changsha, China.
Weixing ZhangDepartment of Thoracic Surgery, Xiangya Hospital, Central South University, Changsha, China.
Haihe JiangDepartment of Thoracic Surgery, Xiangya Hospital, Central South University, Changsha, China.
Yang GaoDepartment of Thoracic Surgery, Xiangya Hospital, Central South University, Changsha, China.
Wei ZhuangDepartment of Thoracic Surgery, Xiangya Hospital, Central South University, Changsha, China.
Kaibo LeiDepartment of Thoracic Surgery, Xiangya Hospital, Central South University, Changsha, China.
Yong TangDepartment of Thoracic Surgery, Xiangya Hospital, Central South University, Changsha, China.
Rongjun WanDepartment of Respiratory and Critical Care Medicine, National Key Clinical Specialty, Xiangya Hospital, Central South University, Changsha, China, leeround@csu.edu.cn.
Central South University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTumor cell dissemination after needle biopsy has been reported in a variety of malignancies, including non-small-cell lung cancer (NSCLC). However, there is little clinical evidence in regard to whether preoperative biopsy increases the risk of recurrence in completely resected NSCLC. PATIENTS AND

methodsA total of 322 patients diagnosed as pathological stage I NSCLC using intraoperative biopsy (IOB) (control group), preoperative percutaneous needle biopsy (PNB) or bronchoscopic biopsy were included in this study. Baseline characteristics were collected and compared. The disease-free survival (DFS) of patients was analyzed using Kaplan-Meier method. Subgroup analysis and Cox regression were performed to evaluate the effect of preoperative biopsy on recurrence risk with adjustment for potential confounders.

resultsAmong these patients, 202 (63%) underwent IOB, 66 (20%) underwent PNB, and 54 (17%) underwent bronchoscopic biopsy. DFS of patients who had preoperative PNB or bronchoscopic biopsy was similar to those who had IOB (

conclusionNeither preoperative PNB nor bronchoscopic biopsy increased the recurrence risk in patients with resected stage I NSCLC, indicating that these procedures could be safely used for diagnosis of early-stage NSCLC.

Indexed as

biopsybron-choscopynon-small-cell lung cancerpercutaneous needle biopsyrecurrencesurgery

Identifiers

PMID30013399
PMCPMC6038855
OpenAlexW2864755014

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.