Evidence map›Paper›PMID 30013388›Full record

ArticleJournal of experimental neuroscience2018

Regional Cerebrovascular Reactivity and Cognitive Performance in Healthy Aging.

Sarah J Catchlove, Todd B Parrish, Yufen Chen, Helen Macpherson, Matthew E Hughes, Andrew Pipingas

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Journal of experimental neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04586049 (Autonomic Dysfunction, Brain Blood Flow and Cognitive Decline in Veterans With Gulf War Illness), which is not on this map. Cited by 34 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 2 pooled it
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04586049 active not recruitingnot on this mapstarted 2023, after this paper: background citation

Autonomic Dysfunction, Brain Blood Flow and Cognitive Decline in Veterans With Gulf War Illness

TypeobservationalSponsorUniversity of Wisconsin, MadisonRan2023 to 2026Enrolled70ConditionsBrain Blood Flow, Neurovascular ControlArmsMRI, Transcranial Doppler Ultrasound, Sympathetic Nerve Activity
3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 2 syntheses or guidelines pooled it, 57 citations in OpenAlex.

  1. Reproducibility of cerebrovascular reactivity measurements: A systematic review of neuroimaging techniquesJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2022
    Pooled it
  2. Pooled it
  3. Sex comparison of cerebrovascular reactivity to COJournal of applied physiology (Bethesda, Md. : 1985) · 2026
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  9. Measuring cerebrovascular reactivity in a hemodialysis cohort.Cerebral circulation - cognition and behavior · 2025
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  11. The dependence of COImaging neuroscience (Cambridge, Mass.) · 2025
    Article
  12. Article
  13. CD8American journal of physiology. Regulatory, integrative and comparative physiology · 2024
    Article
  14. Cerebrovascular Reactivity Following Spinal Cord Injury.Topics in spinal cord injury rehabilitation · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Sarah J CatchloveCentre for Human Psychopharmacology, Swinburne University, Hawthorn, VIC, Australia.ORCID https://orcid.org/0000-0003-2314-1706
Todd B ParrishFeinberg School of Medicine, Northwestern University, Chicago, IL, USA.
Yufen ChenFeinberg School of Medicine, Northwestern University, Chicago, IL, USA.
Helen MacphersonInstitute for Physical Activity and Nutrition, Deakin University, Geelong, VIC, Australia.
Matthew E HughesCentre for Mental Health, Swinburne University, Hawthorn, VIC, Australia.
Andrew PipingasCentre for Human Psychopharmacology, Swinburne University, Hawthorn, VIC, Australia.
Northwestern University · USSwinburne University of Technology · AUDeakin University · AUNational Imaging Facility · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cerebrovascular reactivity (CVR) reflects the response of brain blood vessels to vasoactive stimuli, such as neural activity. The current research assessed age-related changes in regional CVR to 5% CO

Indexed as

Cerebrovascular reactivitycognitionhealthy agingmagnetic resonance imaging (MRI)memory

Identifiers

PMID30013388
PMCPMC6043917
OpenAlexW2856910437

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.