Evidence map›Paper›PMID 30013375›Full record

ArticleInfection and drug resistance2018

Epidemiology and molecular characterization of multidrug-resistant

Elisabet Guiral, Maria Jesús Pons, Delfino Vubil, Marta Marí-Almirall, Betuel Sigaúque, Sara Maria Soto, Pedro Luís Alonso, Joaquim Ruiz, Jordi Vila, Inácio Mandomando

Open access · goldAbstract read
In one paragraph

Article in Infection and drug resistance, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Rabbits as a Reservoir of Multidrug-ResistantAntibiotics (Basel, Switzerland) · 2024
    Article
  4. Article
  5. Article
  6. The Evaluation of EazyplexAntibiotics (Basel, Switzerland) · 2022
    Article
  7. Colistin Resistance and ESBL Production inAntibiotics (Basel, Switzerland) · 2021
    Article
  8. Article
  9. Review
  10. Antibiotic-ResistantThe American journal of tropical medicine and hygiene · 2019
    Article
  11. Review
  12. Antibiotic-Resistance Genes inSaudi journal of medicine & medical sciences
    Article
  13. High prevalence of CTX-M-1 group in ESBL-producing enterobacteriaceae infection in intensive care units in southern Chile.The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Elisabet GuiralBarcelona Institute for Global Health (ISGlobal), Hospital Clínic-Universitat de Barcelona, Barcelona, Spain.
Maria Jesús PonsBarcelona Institute for Global Health (ISGlobal), Hospital Clínic-Universitat de Barcelona, Barcelona, Spain.
Delfino VubilCentro de Investigação em Saúde de Manhiça (CISM), Maputo, Mozambique, inacio.mandomando@manhica.net.
Marta Marí-AlmirallBarcelona Institute for Global Health (ISGlobal), Hospital Clínic-Universitat de Barcelona, Barcelona, Spain.
Betuel SigaúqueCentro de Investigação em Saúde de Manhiça (CISM), Maputo, Mozambique, inacio.mandomando@manhica.net.
Sara Maria SotoBarcelona Institute for Global Health (ISGlobal), Hospital Clínic-Universitat de Barcelona, Barcelona, Spain.
Pedro Luís AlonsoBarcelona Institute for Global Health (ISGlobal), Hospital Clínic-Universitat de Barcelona, Barcelona, Spain.
Joaquim RuizBarcelona Institute for Global Health (ISGlobal), Hospital Clínic-Universitat de Barcelona, Barcelona, Spain.
Jordi VilaBarcelona Institute for Global Health (ISGlobal), Hospital Clínic-Universitat de Barcelona, Barcelona, Spain.
Inácio MandomandoCentro de Investigação em Saúde de Manhiça (CISM), Maputo, Mozambique, inacio.mandomando@manhica.net.
Barcelona Institute for Global Health · ESManhiça Health Research Centre · MZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe emergence and spread of extended-spectrum β-lactamases (ESBLs), especially CTX-M, is an important public health problem with serious implications for low-income countries where second-line treatment is often unavailable. Knowledge of the local prevalence of ESBL is critical to define appropriate empirical therapeutic strategies for multidrug-resistant (MDR) organisms. This study aimed to assess and characterize the presence of ESBL and especially CTX-M-producing MATERIALS AND

methodsOne hundred and fifty-one

resultsApproximately 11% (17/151) of

conclusionOur data suggest the presence of a co-selection of third-generation cephalosporin-resistant determinants in the study area despite limited access to these antibiotics. This highlights the importance of continuous surveillance of antimicrobial resistance of both genetic elements of resistance and resistant isolates in order to monitor the emergence and trends of ESBL-producing isolates to promote adequate therapeutic strategies for the management of MDR bacterial infections.

Indexed as

CTX-M-15Enterobacteriaceaemultidrug-resistanceresistance determinant location

Identifiers

PMID30013375
PMCPMC6037150
OpenAlexW2810655395

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.