Evidence map›Paper›PMID 30013331›Full record

ArticleClinical interventions in aging2018

Prognostic ability of cystatin C and homocysteine plasma levels for long-term outcomes in very old acute myocardial infarction patients.

Zhenhong Fu, Xia Yang, Mingzhi Shen, Hao Xue, Geng Qian, Feng Cao, Jun Guo, Wei Dong, Yundai Chen

Abstract read
In one paragraph

Article in Clinical interventions in aging, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Zhenhong Fu *Department of Cardiology, Chinese People's Liberation Army General Hospital, Beijing, China, fuzhenh@126.com; fuzhenh301@126.com.
Xia Yang *Department of Cardiology, Chinese People's Liberation Army General Hospital, Beijing, China, fuzhenh@126.com; fuzhenh301@126.com.
Mingzhi Shen *Department of Cardiology, Hainan Branch of Chinese People's Liberation Army General Hospital, Sanya, Hainan, China.
Hao Xue *Department of Cardiology, Chinese People's Liberation Army General Hospital, Beijing, China, fuzhenh@126.com; fuzhenh301@126.com.
Geng QianDepartment of Cardiology, Chinese People's Liberation Army General Hospital, Beijing, China, fuzhenh@126.com; fuzhenh301@126.com.
Feng CaoDepartment of Cardiology, Chinese People's Liberation Army General Hospital, Beijing, China, fuzhenh@126.com; fuzhenh301@126.com.
Jun GuoDepartment of Cardiology, Chinese People's Liberation Army General Hospital, Beijing, China, fuzhenh@126.com; fuzhenh301@126.com.
Wei DongDepartment of Cardiology, Chinese People's Liberation Army General Hospital, Beijing, China, fuzhenh@126.com; fuzhenh301@126.com.
Yundai ChenDepartment of Cardiology, Chinese People's Liberation Army General Hospital, Beijing, China, fuzhenh@126.com; fuzhenh301@126.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimsThis study sought to evaluate the prognostic powers of combined use of cystatin C (Cys C) and homocysteine (Hcy) at predicting adverse events of patients >80 years old with acute myocardial infarction (AMI). PATIENTS AND

methodsThe analysis involved 753 patients >80 years old undergoing coronary angiography for chest pain in China from January 2006 to December 2012. Kaplan-Meier method was used for survival and major adverse cardiac events (MACE) rates. Multivariate Cox regression was performed to identify mortality predictors. Receiver operating characteristic curve analysis was performed to predict the cutoff values of Cys C and Hcy for all-cause mortality.

resultsThe duration of follow-up was 40-116 months (median, 63 months; interquartile range, 51-74 months). The long-term survival and event-free survival rates of AMI patients were significantly lower than those of unstable angina pectoris patients (

conclusionCys C is a strong independent predictor of long-term all-cause death and MACE in very old AMI patients. The combined use of Cys C and Hcy further improves the predictive accuracy.

Indexed as

AgedAngina, UnstableBiomarkersChinaCoronary AngiographyCystatin CDisease-Free SurvivalFemaleHomocysteineHumansKaplan-Meier EstimateMaleMyocardial InfarctionPrognosisProportional Hazards ModelsRisk FactorsBiomarkersCystatin CHomocysteineacute myocardial infarctioncystatin Chomocysteineprognosisvery old

Identifiers

PMID30013331
PMCPMC6037277

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.