Evidence map›Paper›PMID 30013193›Full record

ArticleNature chemistry2018

Concerted nucleophilic aromatic substitutions.

Eugene E Kwan, Yuwen Zeng, Harrison A Besser, Eric N Jacobsen

Abstract read
In one paragraph

Article in Nature chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 82 papers.

0numbers the graph read from it
0cells of the map it votes in
82citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

82 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Photothermal Conversion Promotes Challenging SAngewandte Chemie (International ed. in English) · 2026
    Article
  10. Article
  11. Ligand-Controlled Chemodivergent Bismuth Catalysis.Journal of the American Chemical Society · 2025
    Article
  12. Metastable Macrocyclic Bis-Meisenheimer Adduct.Angewandte Chemie (International ed. in English) · 2025
    Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article

22 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Eugene E KwanDepartment of Chemistry & Chemical Biology, Harvard University, Cambridge, MA, USA.ORCID http://orcid.org/0000-0001-7037-0531
Yuwen ZengDepartment of Chemistry & Chemical Biology, Harvard University, Cambridge, MA, USA.
Harrison A BesserDepartment of Chemistry & Chemical Biology, Harvard University, Cambridge, MA, USA.
Eric N JacobsenDepartment of Chemistry & Chemical Biology, Harvard University, Cambridge, MA, USA. jacobsen@chemistry.harvard.edu.ORCID http://orcid.org/0000-0001-7952-3661

Funding

CHIRAL COMPLEXES DESIGNED TO CATALYZE ORGANIC REACTIONSR01GM043214 · NIGMS · UNIVERSITY OF ILLINOIS URBANA-CHAMPAIGN · PI JACOBSEN, ERIC N · 1991 to 2023
$9.4M
Chiral Catalysts Designed to Catalyze Organic ReactionsR37GM043214 · NIGMS · HARVARD UNIVERSITY · PI JACOBSEN, ERIC N · 2002 to 2011
$6.6M
NIGMS NIH HHS R01 GM043214NIGMS NIH HHS R37 GM043214
6 · The paper itself

Abstract

Nucleophilic aromatic substitution (S

Indexed as

Benzene DerivativesCarbonCarbon IsotopesFluorineIsotope LabelingKineticsMagnetic Resonance SpectroscopyBenzene DerivativesCarbonCarbon-13Carbon IsotopesFluorine

Identifiers

PMID30013193
PMCPMC6105541

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.