ArticleNature immunology2018
Epithelial damage and tissue γδ T cells promote a unique tumor-protective IgE response.
Article in Nature immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
65 citing papers in PubMed, 115 citations in OpenAlex.
- The multifaceted roles of tumor-infiltrating plasma cells in cancer immunology.Fundamental research · 2026Review
- Review
- IgE Production Beyond Classical T-Cell Help.Immune network · 2026Review
- AllergoOncology: Emerging Translational and Clinical Significance of Basophils and Mast Cells in Cancer.Clinical and translational allergy · 2026Review
- Eosinophils and Bioactive Lipid Mediators Regulate Skin Inflammation and Cancer Growth.The Journal of investigative dermatology · 2025Article
- Mendelian Randomization Combined with Bioinformatics Revealed Specific Allergy-Mediated Protective Mechanisms Against Renal Cell Carcinoma.Phenomics (Cham, Switzerland) · 2025Article
- Cutaneous T cell immunity.Nature immunology · 2025Review
- The IL-33/ST2 axis and tissue Treg maintain epithelial homeostasis and restrain cancer development in the skin.Cell reports · 2025Article
- Maternal IgE Influence on Fetal and Infant Health.Immunological reviews · 2025Review
- Engrafted NSG-SGM3 humanized mice spontaneously produce human immunoglobulins including IgE.Frontiers in immunology · 2025Article
- Identification of B cell antigens in solid cancer: initial insights and functional implications.Frontiers in immunology · 2025Review
- TSLP: contrasting roles in cancer.Frontiers in immunology · 2025Review
- Primordial Cells Bridging the Gap Between Innate and Adaptive Immunity.Advances in experimental medicine and biology · 2025Review
- Anti-Tumor Effects ofToxins · 2024Article
- Type 2 immunity in the brain and brain borders.Cellular & molecular immunology · 2023Review
- TGFβ control of immune responses in cancer: a holistic immuno-oncology perspective.Nature reviews. Immunology · 2023Review
- Antibody-mediated regulation of basophils: emerging views and clinical implications.Trends in immunology · 2023Review
- IL-4Rα signalling in B cells and T cells play differential roles in acute and chronic atopic dermatitis.Scientific reports · 2023Article
- Prospective assessment of pre-existing andFrontiers in immunology · 2023Article
- The capability of heterogeneous γδ T cells in cancer treatment.Frontiers in immunology · 2023Review
5 more citing papers are in PubMed but not listed here.
Corrections and comments
- Commented on by
- Commented on by
Authors and funding
16 authors at 8 institutions in 1 country.
Funding
Abstract
IgE is an ancient and conserved immunoglobulin isotype with potent immunological function. Nevertheless, the regulation of IgE responses remains an enigma, and evidence of a role for IgE in host defense is limited. Here we report that topical exposure to a common environmental DNA-damaging xenobiotic initiated stress surveillance by γδTCR
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.