ArticleNature communications2018
Root exudate metabolites drive plant-soil feedbacks on growth and defense by shaping the rhizosphere microbiota.
Article in Nature communications, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 504 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
504 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- How Useful Are Plant Traits in Explaining Variation in Phyllosphere Microbial Abundance and Composition Across Hosts?Environmental microbiology · 2025Pooled it
- Meta-analysis reveals the effects of microbial inoculants on the biomass and diversity of soil microbial communities.Nature ecology & evolution · 2024Pooled it
- Root colonization by beneficial rhizobacteria.FEMS microbiology reviews · 2024Pooled it
- From genotype to microbiome function: a gene-metabolite-microbiome pathway shaping plant nutrient acquisition.The New phytologist · 2026Article
- Dynamic Rhizodeposition in the Woody Perennial Populus trichocarpa.Plant, cell & environment · 2026Article
- Metal-Phenolic Complexation Governs Soil Mineral Crystallinity to Enhance Crop Growth.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Jasmonic and salicylic acid pathways shape the rhizosphere microbiome, affecting aphid herbivory and soil-mediated insect-plant interactions in a density-dependent manner.Plant & cell physiology · 2026Article
- Evolutionary divergence and regulatory landscapes of benzoxazinoid metabolism in monocot crops.Plant cell reports · 2026Review
- Ecological Mechanisms Underlying the Effects of Forest-Medicinal Plant Agroforestry Systems on Soil Quality and the Understory Environment.Plants (Basel, Switzerland) · 2026Review
- Ecological Management of Crown Gall-Affected Soils: Pathogen Reservoirs, Disease-Suppressive Microbiomes, and Helper Consortia.Microorganisms · 2026Review
- It takes a village: how plant-associated bacterial communities socialise to shape plant growth and health.Essays in biochemistry · 2026Review
- Review
- Root anatomical traits modulate the assembly and nitrogen-transformation potential of root-associated microbiomes in a temperate steppe.The New phytologist · 2026Article
- Revisiting plant-microbe interaction mechanisms for developing efficient biostimulants.Folia microbiologica · 2026Review
- Non-volatile plant metabolites as chemical signals: linking resilience to ecological sustainability under climate change.Plant cell reports · 2026Article
- Light-Root Microbiome Interactions in Vegetable Crops: From Photoreceptor Signaling to Exudate-Mediated Recruitment.International journal of molecular sciences · 2026Review
- Article
- Breeding for beneficial microbial associations.Nature communications · 2026Review
- Harnessing plant-exuded prebiotics as a next-generation strategy for sustainable agriculture.Journal of integrative plant biology · 2026Review
- Arbuscular Mycorrhizal Fungus System Recruits Sphingomonas spp. to Enhance Drought Resistance in Peanut.Plant, cell & environment · 2026Article
444 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
Abstract
By changing soil properties, plants can modify their growth environment. Although the soil microbiota is known to play a key role in the resulting plant-soil feedbacks, the proximal mechanisms underlying this phenomenon remain unknown. We found that benzoxazinoids, a class of defensive secondary metabolites that are released by roots of cereals such as wheat and maize, alter root-associated fungal and bacterial communities, decrease plant growth, increase jasmonate signaling and plant defenses, and suppress herbivore performance in the next plant generation. Complementation experiments demonstrate that the benzoxazinoid breakdown product 6-methoxy-benzoxazolin-2-one (MBOA), which accumulates in the soil during the conditioning phase, is both sufficient and necessary to trigger the observed phenotypic changes. Sterilization, fungal and bacterial profiling and complementation experiments reveal that MBOA acts indirectly by altering root-associated microbiota. Our results reveal a mechanism by which plants determine the composition of rhizosphere microbiota, plant performance and plant-herbivore interactions of the next generation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.