Evidence map›Paper›PMID 30013004›Full record

ArticleInternational journal of molecular sciences2018

The Natural Product 6-Gingerol Inhibits Inflammation-Associated Osteoclast Differentiation via Reduction of Prostaglandin E₂ Levels.

Youn-Hwan Hwang, Taesoo Kim, Rajeong Kim, Hyunil Ha

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 62 citations in OpenAlex.

  1. Article
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  4. Review
  5. Article
  6. Potential mechanism of gingerFrontiers in pharmacology · 2025
    Review
  7. Article
  8. Article
  9. Review
  10. Phytogenics in Ginger,Animals : an open access journal from MDPI · 2023
    Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. Review
  16. Article
  17. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Youn-Hwan HwangHerbal Medicine Research Division, Korea Institute of Oriental Medicine, Daejeon 34054, Korea. hyhhwang@kiom.re.kr.ORCID 0000-0002-4959-2436
Taesoo KimHerbal Medicine Research Division, Korea Institute of Oriental Medicine, Daejeon 34054, Korea. xotn91@kiom.re.kr.
Rajeong KimHerbal Medicine Research Division, Korea Institute of Oriental Medicine, Daejeon 34054, Korea. younme1112@nate.com.
Hyunil HaHerbal Medicine Research Division, Korea Institute of Oriental Medicine, Daejeon 34054, Korea. hyunil74@kiom.re.kr.
Korea Institute of Oriental Medicine · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The natural product 6-gingerol, a major bioactive component of the rhizome of ginger (

Indexed as

AnimalsBiological ProductsCatecholsCell DifferentiationCells, CulturedCoculture TechniquesDinoprostoneFatty AlcoholsGene ExpressionInflammationInterleukin-1MaleMice, Inbred ICROsteoblastsOsteoclastsRANK LigandBiological ProductsCatecholsDinoprostoneFatty AlcoholsgingerolInterleukin-1RANK Ligand6-gingerolinflammationinterleukin-1osteoclastprostaglandin E2

Identifiers

PMID30013004
PMCPMC6073224
OpenAlexW2884100091

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.