Evidence map›Paper›PMID 30012991›Full record

ArticlePathogens (Basel, Switzerland)2018

Preparation of Poly (dl-Lactide-co-Glycolide) Nanoparticles Encapsulated with Periglaucine A and Betulinic Acid for In Vitro Anti-

Tooba Mahboob, Muhammad Nawaz, Tan Tian-Chye, Chandramathi Samudi, Christophe Wiart, Veeranoot Nissapatorn

Abstract read
In one paragraph

Article in Pathogens (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Anti-Scientifica · 2026
    Article
  2. Review
  3. Article
  4. Hydrothermal Synthesis of β-NbInternational journal of molecular sciences · 2022
    Article
  5. Amoebicidal activity ofParasitology · 2021
    Article
  6. Article
  7. Article
  8. Pathogens and global health · 2020
    Article
  9. Article
  10. Acanthamoeba in Southeast Asia - Overview and Challenges.The Korean journal of parasitology · 2019
    Review
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Tooba MahboobDepartment of Parasitology, Faculty of Medicine, University of Malaya, Kuala Lumpur 50603, Malaysia. tooba666@hotmail.com.
Muhammad NawazDepartment of Nano-Medicine Research, Institute for Research and Medical Consultations (IRMC), Imam Abdulrahman Bin Faisal University, P.O. Box 1982, Dammam 31441, Saudi Arabia. mnnmuhammad@iau.edu.sa.
Tan Tian-ChyeDepartment of Parasitology, Faculty of Medicine, University of Malaya, Kuala Lumpur 50603, Malaysia. tantianchye@um.edu.my.
Chandramathi SamudiDepartment of Medical Microbiology, Faculty of Medicine, University of Malaya, Kuala Lumpur 50603, Malaysia. chandramathi@um.edu.my.
Christophe WiartSchool of Pharmacy, Nottingham University Malaysia Campus, Semenyih, Selangor, Kuala Lumpur 43500, Malaysia. christophe.wiart@nottingham.edu.my.
Veeranoot NissapatornDepartment of Parasitology, Faculty of Medicine, University of Malaya, Kuala Lumpur 50603, Malaysia. nissapat@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Poly (dl-lactide-co-glycolide) (PLGA) microspheres were synthesized as delivery system for the natural anti-parasitic compounds, Periglaucine A (PGA) and Betulinic acid (BA). Periglaucine A and Betulinic acid were encapsulated in PLGA nanoparticles by single emulsion method with an average particle size of approximately 100⁻500 nm. Periglaucine A and Betulinic acid encapsulation efficiency was observed to be 90% and 35% respectively. Anti-

Indexed as

anti-Acanthamoebabetulinic acidcytotoxicityperiglaucine APLGA-nanoparticles

Identifiers

PMID30012991
PMCPMC6161289

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.