Evidence map›Paper›PMID 30012937›Full record

ArticleFukushima journal of medical science2018

Feasibility of skin acetone analysis in patients with cardiovascular diseases.

Tetsuro Yokokawa, Takamasa Sato, Satoshi Suzuki, Masayoshi Oikawa, Akiomi Yoshihisa, Atsushi Kobayashi, Takayoshi Yamaki, Hiroyuki Kunii, Kazuhiko Nakazato, Takafumi Ishida and 1 more

Open access · diamondAbstract read
In one paragraph

Article in Fukushima journal of medical science, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Tetsuro YokokawaDepartment of Cardiovascular Medicine, Fukushima Medical University.
Takamasa SatoDepartment of Cardiovascular Medicine, Fukushima Medical University.
Satoshi SuzukiDepartment of Cardiovascular Medicine, Fukushima Medical University.
Masayoshi OikawaDepartment of Cardiovascular Medicine, Fukushima Medical University.
Akiomi YoshihisaDepartment of Cardiovascular Medicine, Fukushima Medical University.
Atsushi KobayashiDepartment of Cardiovascular Medicine, Fukushima Medical University.
Takayoshi YamakiDepartment of Cardiovascular Medicine, Fukushima Medical University.
Hiroyuki KuniiDepartment of Cardiovascular Medicine, Fukushima Medical University.
Kazuhiko NakazatoDepartment of Cardiovascular Medicine, Fukushima Medical University.
Takafumi IshidaDepartment of Cardiovascular Medicine, Fukushima Medical University.
Yasuchika TakeishiDepartment of Cardiovascular Medicine, Fukushima Medical University.
Fukushima Medical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBreath acetone is reported to be a noninvasive biomarker for heart failure. However, the measurement of this metabolite requires expertize and is not standardized yet. Acetone is also released from the skin; thus, measuring acetone as a skin gas may be easier than breath analysis.

methodsWe analyzed skin acetone collected from 41 hospitalized patients with cardiovascular diseases. Passive samplers were used to measure skin acetone emission. Passive sampler was softly fixed on the surface of forearm skin for 10 hour at night.

resultsSkin acetone emission ranged from 0.00 to 2.70 ng/cm

conclusionsThis is the first study to analyze skin gas in patients with cardiovascular diseases. Skin acetone emission was found to reflect blood ketone bodies. It is feasible to measure skin acetone emission for reflecting blood ketone bodies in patients with cardiovascular diseases.

Indexed as

AcetoneAdultAgedCardiovascular DiseasesFeasibility StudiesFemaleHumansKetone BodiesMaleMiddle AgedProspective StudiesSkinAcetoneKetone Bodiesbiogas analysiscardiovascular diseasesketone bodySkin acetone

Identifiers

PMID30012937
PMCPMC6141450
OpenAlexW2884709409

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.