Evidence map›Paper›PMID 30012811›Full record

ArticleThe British journal of general practice : the journal of the Royal College of General Practitioners2018

Chronic kidney disease and cause-specific hospitalisation: a matched cohort study using primary and secondary care patient data.

Masao Iwagami, Ben Caplin, Liam Smeeth, Laurie A Tomlinson, Dorothea Nitsch

Open access · hybridAbstract read
In one paragraph

Article in The British journal of general practice : the journal of the Royal College of General Practitioners, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.

  1. The association between chronic kidney disease, falls, and fractures: a systematic review and meta-analysis.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2020
    Pooled it
  2. Article
  3. International Environmental Impact of CKD Care.Kidney international reports · 2026
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  12. Hospital admission after primary care consultation for community-onset lower urinary tract infection: a cohort study of risks and predictors using linked data.The British journal of general practice : the journal of the Royal College of General Practitioners · 2023
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  13. Article
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  17. Observational
  18. Uncoded chronic kidney disease in primary care: a cross-sectional study of inequalities and cardiovascular disease risk management.The British journal of general practice : the journal of the Royal College of General Practitioners · 2020
    Article
  19. Article
  20. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Masao IwagamiDepartment of Non-communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, London.
Ben CaplinCentre for Nephrology, University College London, London.
Liam SmeethDepartment of Non-communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, London.
Laurie A TomlinsonDepartment of Non-communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, London.
Dorothea NitschDepartment of Non-communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, London.
London School of Hygiene & Tropical Medicine · GBLondon Centre for Nanotechnology · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlthough chronic kidney disease (CKD) is associated with various outcomes, the burden of each condition for hospital admission is unknown.

aimTo quantify the association between CKD and cause-specific hospitalisation. DESIGN AND

settingA matched cohort study in primary care using Clinical Practice Research Datalink linked to Hospital Episode Statistics in England.

methodPatients with CKD (estimated glomerular filtration rate <60 mL/min/1.73 m

resultsIn a cohort of 242 349 pairs of patients, with and without CKD, the rate difference was largest for heart failure at 6.6/1000 person-years (9.7/1000 versus 3.1/1000 person-years in patients with and without CKD, respectively), followed by urinary tract infection at 5.2, pneumonia at 4.4, and AKI at 4.1/1000 person-years. The relative risk was highest for AKI with a fully adjusted hazard ratio of 4.90, 95% confidence interval (CI) = 4.47 to 5.38, followed by heart failure with 1.66, 95% CI = 1.59 to 1.75.

conclusionHospitalisations for heart failure, infection, and AKI showed strong associations with CKD in absolute and(or) relative terms, suggesting targets for improved preventive care.

Indexed as

Primary Health CareSecondary Health CareAdultCohort StudiesDatabases, FactualDisease ProgressionElectronic Health RecordsEnglandFemaleFollow-Up StudiesHospitalizationHumansMaleMiddle AgedRenal Insufficiency, Chronicacute kidney injurychronic kidney diseasesgeneral practiceheart failurehospitalisationinfection

Identifiers

PMID30012811
PMCPMC6058621
OpenAlexW2884455172

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.