Evidence map›Paper›PMID 30012795›Full record

ArticleBMJ open2018

Prognostic implications of left ventricular strain by speckle-tracking echocardiography in population-based studies: a systematic review protocol of the published literature.

Lamia Al Saikhan, Chloe Park, Rebecca Hardy, Alun Hughes

Abstract read
In one paragraph

Article in BMJ open, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  7. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Lamia Al SaikhanInstitute of Cardiovascular Science, School of Life and Medical Sciences, University College London, London, UK.ORCID 0000-0002-9951-8832
Chloe ParkInstitute of Cardiovascular Science, School of Life and Medical Sciences, University College London, London, UK.
Rebecca HardyMRC Unit for Lifelong Health and Ageing, University College London, London, UK.
Alun HughesInstitute of Cardiovascular Science, School of Life and Medical Sciences, University College London, London, UK.

Funding

Medical Research Council MC_UU_12019/1
6 · The paper itself

Abstract

introductionLeft ventricular (LV) strain by speckle-tracking echocardiography (STE) is a comparatively new prognostic marker. Meta-analyses relating LV strain by STE to outcomes have been conducted in selected patient-based populations with established or suspected cardiovascular (CV) diseases. However, the evidence related to population-based studies of community-dwelling individuals is uncertain. The aim of this study is to provide a comprehensive systematic review and analysis of the current available literature regarding LV strain by STE as a predictor of adverse outcomes in population-based studies. METHODS AND ANALYSES: Thesaurus and text-word searching will be used to search two online databases (MEDLINE and EMBASE) and additional sources will be identified from citation metrics and reference lists' search. Dual search results' screening, data extraction and quality assessment will be performed. Cohort studies of community/population-based samples who have had STE and followed up longitudinally for mortal and morbid events, and published in English and peer-reviewed journals will be included. Primary outcome will be all-cause mortality whereas secondary outcomes will be composite cardiac and CV end points. Risk of bias will be assessed using Newcastle-Ottawa Quality Assessment Scale of cohort studies that will be modified as appropriate. Any arising discrepancies will be discussed and resolved through consensus. ETHICS AND DISSEMINATION: Ethical approval is not required as this is a protocol for a systematic review. The findings of this study will be presented at scientific conferences and published in a peer-reviewed journal. Any amendments to the protocol will be documented and updated in the PROSPERO registry. PROSPERO REGISTRATION NUMBER: CRD42018090302.

Indexed as

Ventricular Function, LeftCardiovascular DiseasesEchocardiographyHeart VentriclesHumansIndependent LivingMortalityPrognosisSystematic Reviews as Topiccardiovascular diseasecommunity dwelling individualsleft ventricular strainmortalityspeckle tracking echocardiography

Identifiers

PMID30012795
PMCPMC6082461

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.