Evidence map›Paper›PMID 30012758›Full record

ArticleAntimicrobial agents and chemotherapy2018

Effect of the Synthetic Bile Salt Analog CamSA on the Hamster Model of Clostridium difficile Infection.

Amber Howerton, Cale O Seymour, Senthil K Murugapiran, Zhenlin Liao, Jacqueline R Phan, Alan Estrada, Adam J Wagner, Chrisabelle C Mefferd, Brian P Hedlund, Ernesto Abel-Santos

Abstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 37 citations in OpenAlex.

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  16. Anti-virulence strategies forGut microbes · 2020
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  17. Article
  18. Clinics in colon and rectal surgery · 2020
    Review
  19. Relationship between remote cholecystectomy and incident Clostridioides difficile infection.Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases · 2019
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Amber HowertonDepartment of Physical and Life Sciences, Nevada State College, Henderson, Nevada, USA.
Cale O SeymourSchool of Life Sciences, University of Nevada, Las Vegas, Las Vegas, Nevada, USA.
Senthil K MurugapiranSchool of Life Sciences, University of Nevada, Las Vegas, Las Vegas, Nevada, USA.
Zhenlin LiaoCollege of Food Science, South China Agricultural University, Guangzhou, People's Republic of China.
Jacqueline R PhanDepartment of Chemistry, University of Nevada, Las Vegas, Las Vegas, Nevada, USA.
Alan EstradaDepartment of Physical and Life Sciences, Nevada State College, Henderson, Nevada, USA.
Adam J WagnerDepartment of Physical and Life Sciences, Nevada State College, Henderson, Nevada, USA.
Chrisabelle C MefferdSchool of Life Sciences, University of Nevada, Las Vegas, Las Vegas, Nevada, USA.
Brian P HedlundSchool of Life Sciences, University of Nevada, Las Vegas, Las Vegas, Nevada, USA.
Ernesto Abel-SantosSchool of Life Sciences, University of Nevada, Las Vegas, Las Vegas, Nevada, USA ernesto.abelsantos@unlv.edu.
University of Nevada, Las Vegas · USNevada State University · USSouth China Agricultural University · CN

Funding

Using bile salt metabolism to modulate CDI prophylaxisR01AI109139 · NIAID · UNIVERSITY OF NEVADA LAS VEGAS · PI Ernesto V Abel-Santos · 2015 to 2026
$5.4M
NIAID NIH HHS R01 AI109139
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsAnti-Bacterial AgentsBile Acids and SaltsClostridioides difficileClostridium InfectionsCricetinaeFemaleVancomycinAnti-Bacterial AgentsBile Acids and SaltsVancomycinantigerminationCamSAC. difficilehamstermicrobiome

Identifiers

PMID30012758
PMCPMC6153836
OpenAlexW2884242898

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.