Evidence map›Paper›PMID 30012717›Full record

ArticleJournal of lipid research2018

Effect of antiretroviral therapy on allele-associated Lp(a) level in women with HIV in the Women's Interagency HIV Study.

Byambaa Enkhmaa, Erdembileg Anuurad, Wei Zhang, Chin-Shang Li, Robert Kaplan, Jason Lazar, Dan Merenstein, Roksana Karim, Brad Aouizerat, Mardge Cohen and 6 more

Open access · hybridAbstract read
In one paragraph

Article in Journal of lipid research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 12 institutions in 1 country.

Byambaa EnkhmaaDepartments of Internal Medicine University of California, Davis, Davis, CA 95616 ebyambaa@ucdavis.edu.
Erdembileg AnuuradDepartments of Internal Medicine University of California, Davis, Davis, CA 95616.
Wei ZhangDepartments of Internal Medicine University of California, Davis, Davis, CA 95616.
Chin-Shang LiPublic Health Sciences, University of California, Davis, Davis, CA 95616.
Robert KaplanDepartment of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY 10461.
Jason LazarDepartment of Cardiovascular Disease, State University of New York Downstate Medical Center, Brooklyn, NY 11203.
Dan MerensteinDepartment of Family Medicine, Georgetown University Medical Center, Washington, DC 20007.
Roksana KarimDepartment Preventive Medicine, University of Southern California, Los Angeles, Los Angeles, CA 90007.
Brad AouizeratDepartment of Oral and Maxillofacial Surgery, New York University, New York, NY 10003.
Mardge CohenDepartment of Medicine, Rush University and Stroger Hospital, Cook County Bureau of Health Services, Chicago, IL 60612.
Kenneth ButlerDivision of Geriatric Medicine/Gerontology, University of Mississippi Medical Center, Jackson, MS 39216.
Savita PahwaMiami Center for AIDS Research, University of Miami, Miami, FL 33136.
Igho OfotokunDepartment of Medicine, Infectious Diseases, Emory School of Medicine, Atlanta, GA 30307.
Adaora A AdimoraDivision of Infectious Diseases, University of North Carolina, Chapel Hill, NC 27599.
Elizabeth GolubDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205.
Lars BerglundDepartments of Internal Medicine University of California, Davis, Davis, CA 95616.
University of California, Davis · USAlbert Einstein College of Medicine · USEmory University · USGeorgetown University · USJohn H. Stroger, Jr. Hospital of Cook County · USJohns Hopkins University · USNew York University · USSUNY Downstate Health Sciences University · USUniversity of Miami · USUniversity of Mississippi Medical Center · USUniversity of North Carolina at Chapel Hill · USUniversity of Southern California · US

Funding

Virology CoreP30AI027763 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MALLORY O JOHNSON · 1988 to 2026
$93.6M
Engaging University of California Stakeholders for Biorespository ResearchUL1TR000004 · NCATS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI GRANDIS, JENNIFER RUBIN · 2012 to 2015
$78.0M
Virology, Immunology, and Microbiology CoreP30AI050410 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI DAVID M. MARGOLIS · 2001 to 2026
$76.9M
Virology and Molecular Biomarkers CoreP30AI050409 · NIAID · EMORY UNIVERSITY · PI Ann M Chahroudi, Colleen F Kelley · 2002 to 2026
$74.0M
Women's Interagency HIV Study (WIHS-V)U01AI035004 · NIAID · MONTEFIORE MEDICAL CENTER (BRONX, NY) · PI ANASTOS, KATHRYN M., SHARMA, ANJALI · 1993 to 2018
$65.7M
WOMEN'S INTERAGENCY HIV STUDY ORGANIZATION, MANAGEMENT AND COMMUNICATIONSU01AI034989 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI AOUIZERAT, BRADLEY E, GREENBLATT, RUTH MARTHA · 1993 to 2018
$65.6M
Women's Interagency HIV Study (WIHS) IIIU01AI031834 · NIAID · SUNY DOWNSTATE MEDICAL CENTER · PI GUSTAFSON, DEBORAH R., MINKOFF, HOWARD · 1998 to 2018
$53.5M
WOMEN'S INTERAGENCY HIV STUDY (WIHS) ORGANIZATION AND MANAGEMENTU01AI034994 · NIAID · GEORGETOWN UNIVERSITY · PI KASSAYE, SEBLE G · 1993 to 2018
$52.0M
Women's Interagency HIV Study (WIHS) IV, Chicago ConsortiumU01AI034993 · NIAID · HEKTOEN INSTITUTE FOR MEDICAL RESEARCH · PI COHEN, MARDGE H, FRENCH, AUDREY · 1994 to 2018
$51.0M
UC Davis Clinical and Translational Science CenterUL1TR001860 · NCATS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI KENYON, NICHOLAS J., LYLES, COURTNEY REES · 2016 to 2025
$47.3M
WOMENS INTERAGENCY HIV STUDY (WIHS)U01HD032632 · NICHD · UNIVERSITY OF SOUTHERN CALIFORNIA · PI MILAM, JOEL E · 1994 to 2012
$42.0M
WIHS DATA MANAGEMENT AND ANALYSIS CENTER(WDMAC)U01AI042590 · NIAID · JOHNS HOPKINS UNIVERSITY · PI GANGE, STEPHEN J, GOLUB, ELIZABETH T · 1998 to 2018
$38.4M
NCATS NIH HHS UL1 TR000004NCATS NIH HHS UL1 TR000454NCATS NIH HHS UL1 TR001860NHLBI NIH HHS R01 HL083760NHLBI NIH HHS R01 HL095140NHLBI NIH HHS R01 HL126543NHLBI NIH HHS R01 HL132794NHLBI NIH HHS U01 HL146194NIAID NIH HHS P30 AI027763NIAID NIH HHS P30 AI050409NIAID NIH HHS P30 AI050410NIAID NIH HHS U01 AI031834NIAID NIH HHS U01 AI034989NIAID NIH HHS U01 AI034993NIAID NIH HHS U01 AI034994NIAID NIH HHS U01 AI035004NIAID NIH HHS U01 AI042590NIAID NIH HHS U01 AI103390NIAID NIH HHS U01 AI103397NIAID NIH HHS U01 AI103401NIAID NIH HHS U01 AI103408NICHD NIH HHS K12 HD051958NICHD NIH HHS U01 HD032632
6 · The paper itself

Abstract

We previously demonstrated an association between lipoprotein (a) [Lp(a)] levels and atherosclerosis in human immunodeficiency virus (HIV)-seropositive women. The effects of antiretroviral therapy (ART) on Lp(a) levels in relation to apo(a) size polymorphism remain unclear. ART effects on allele-specific apo(a) level (ASL), an Lp(a) level associated with individual apo(a) alleles within each allele-pair, were determined in 126 HIV-seropositive women. ART effects were tested by a mixed-effects model across pre-ART and post-ART first and third visits. Data from 120 HIV-seronegative women were used. The mean age was 38 years; most were African-American (∼70%). Pre-ART ASLs associated with the larger (4.6 mg/dl vs. 8.0 mg/dl,

Indexed as

AllelesAdultAnti-HIV AgentsApoprotein(a)Cohort StudiesFemaleHepatitis CHIV SeropositivityHumansLipoprotein(a)PhenotypeRiskTreatment OutcomeAnti-HIV AgentsApoprotein(a)Lipoprotein(a)apolipoprotein (a) sizesapolipoproteinsbiomarkersclinical studiesdrug therapyhuman immunodeficiency virus treatmentlipoprotein (a)lipoproteinslongitudinal designmolecular biology/geneticsprospective cohort

Identifiers

PMID30012717
PMCPMC6168315
OpenAlexW2884901028

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.