Evidence map›Paper›PMID 30012692›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2018

The Transmembrane Domain of Synaptobrevin Influences Neurotransmitter Flux through Synaptic Fusion Pores.

Chung-Wei Chiang, Che-Wei Chang, Meyer B Jackson

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. The function of VAMP2 in mediating membrane fusion: An overview.Frontiers in molecular neuroscience · 2022
    Review
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Chung-Wei ChiangDepartment of Neuroscience.
Che-Wei ChangDepartment of Neuroscience.
Meyer B JacksonDepartment of Neuroscience, Meyer.Jackson@Wisc.edu.ORCID 0000-0003-2904-7091
University of Wisconsin–Madison · USApplied BioPhysics (United States) · US

Funding

Single-Channel Studies of the Fusion PoreR01NS044057 · NINDS · UNIVERSITY OF WISCONSIN-MADISON · PI JACKSON, MEYER B. · 2002 to 2022
$5.7M
NINDS NIH HHS R01 NS044057
6 · The paper itself

Abstract

The soluble

Indexed as

Amino Acid SubstitutionAnimalsBiological TransportCalciumComputer SimulationDiffusionExocytosisFemaleGene Knockout TechniquesGlutamic AcidHippocampusKineticsMaleMembrane FusionMiceMiniature Postsynaptic PotentialsCalciumGlutamic AcidSNARE ProteinsTryptophanVesicle-Associated Membrane Protein 2exocytosisneurosecretionsynapsesynaptobrevin

Identifiers

PMID30012692
PMCPMC6083459
OpenAlexW2884218538

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.