Evidence map›Paper›PMID 30012638›Full record

ArticleInfection and immunity2018

Evaluation of Adenylate Cyclase Toxoid Antigen in Acellular Pertussis Vaccines by Using a Bordetella pertussis Challenge Model in Mice.

Dylan T Boehm, Jesse M Hall, Ting Y Wong, Andrea M DiVenere, Emel Sen-Kilic, Justin R Bevere, Shelby D Bradford, Catherine B Blackwood, Cody M Elkins, Katherine A DeRoos and 7 more

Open access · bronzeAbstract read
In one paragraph

Article in Infection and immunity, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 45 citations in OpenAlex.

  1. Article
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  7. Review
  8. Pathogens and global health · 2023
    Review
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  20. Highlights of the 12th International Bordetella Symposium.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 3 institutions in 1 country.

Dylan T BoehmDepartment of Microbiology, Immunology, and Cell Biology, West Virginia University, Morgantown, West Virginia, USA.
Jesse M HallDepartment of Microbiology, Immunology, and Cell Biology, West Virginia University, Morgantown, West Virginia, USA.
Ting Y WongDepartment of Microbiology, Immunology, and Cell Biology, West Virginia University, Morgantown, West Virginia, USA.
Andrea M DiVenereDepartment of Chemical Engineering, University of Texas at Austin, Austin, Texas, USA.
Emel Sen-KilicDepartment of Microbiology, Immunology, and Cell Biology, West Virginia University, Morgantown, West Virginia, USA.
Justin R BevereDepartment of Microbiology, Immunology, and Cell Biology, West Virginia University, Morgantown, West Virginia, USA.
Shelby D BradfordDepartment of Microbiology, Immunology, and Cell Biology, West Virginia University, Morgantown, West Virginia, USA.
Catherine B BlackwoodDepartment of Microbiology, Immunology, and Cell Biology, West Virginia University, Morgantown, West Virginia, USA.
Cody M ElkinsDepartment of Microbiology, Immunology, and Cell Biology, West Virginia University, Morgantown, West Virginia, USA.
Katherine A DeRoosDepartment of Microbiology, Immunology, and Cell Biology, West Virginia University, Morgantown, West Virginia, USA.
Mary C GrayDepartment of Medicine, Division of Infectious Diseases and International Health, University of Virginia, Charlottesville, Virginia, USA.
C Garret CooperVaccine Development Center at West Virginia University Health Sciences Center, Morgantown, West Virginia, USA.
Melinda E VarneyDepartment of Microbiology, Immunology, and Cell Biology, West Virginia University, Morgantown, West Virginia, USA.
Jennifer A MaynardDepartment of Chemical Engineering, University of Texas at Austin, Austin, Texas, USA.ORCID https://orcid.org/0000-0002-0363-8486
Erik L HewlettDepartment of Medicine, Division of Infectious Diseases and International Health, University of Virginia, Charlottesville, Virginia, USA.
Mariette BarbierDepartment of Microbiology, Immunology, and Cell Biology, West Virginia University, Morgantown, West Virginia, USA.
F Heath DamronDepartment of Microbiology, Immunology, and Cell Biology, West Virginia University, Morgantown, West Virginia, USA fdamron@hsc.wvu.edu.ORCID https://orcid.org/0000-0002-3140-402X
West Virginia University · USThe University of Texas at Austin · USUniversity of Virginia · US

Funding

WV INBRE: The Inhibitor of Growth Family Member 4 (ING4) inhibits L-Type Amino Acid Transporter 1 (LAT1) expression to suppress Breast CancerP20GM103434 · NIGMS · MARSHALL UNIVERSITY · PI Travis Salisbury · 2012 to 2026
$61.1M
West Virginia Flow Cytometry Core FacilityP30GM103488 · NIGMS · WEST VIRGINIA UNIVERSITY · PI GIBSON, LAURA F. · 2012 to 2016
$4.8M
Systematic evaluation of B. pertussis ACT’s role as a protective antigenR01AI122753 · NIAID · UNIVERSITY OF TEXAS AT AUSTIN · PI MAYNARD, JENNIFER A · 2016 to 2020
$1.9M
Special Becton Dickinson Fortessa Flow CytometerS10OD016165 · OD · WEST VIRGINIA UNIVERSITY · PI CUFF, CHRISTOPHER F · 2013 to 2013
$384k
NIAID NIH HHS HHSN272201200005CNIAID NIH HHS R01 AI122753NIGMS NIH HHS P20 GM103434NIGMS NIH HHS P30 GM103488NIH HHS S10 OD016165
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Adenylyl CyclasesAnimalsAntibodies, BacterialAntibodies, NeutralizingBordetella pertussisDrug Evaluation, PreclinicalHumansMicePertussis VaccineToxoidsWhooping CoughAdenylyl CyclasesAntibodies, BacterialAntibodies, NeutralizingPertussis VaccineToxoidsacellular pertussis vaccinesadenylate cyclase toxinBordetella pertussisDTaPpertussisvaccineswhooping cough

Identifiers

PMID30012638
PMCPMC6204743
OpenAlexW2883573711

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.