Evidence map›Paper›PMID 30012607›Full record

Trial reportProceedings of the National Academy of Sciences of the United States of America2018

Cognitive impairments by alcohol and sleep deprivation indicate trait characteristics and a potential role for adenosine A

Eva-Maria Elmenhorst, David Elmenhorst, Sibylle Benderoth, Tina Kroll, Andreas Bauer, Daniel Aeschbach

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Proceedings of the National Academy of Sciences of the United States of America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

  1. Trial
  2. Sleep and Disorders of Gut-Brain Interaction.Gastroenterology & hepatology · 2026
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  5. Observational
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  7. Article
  8. Total Sleep Deprivation Increases Brain Age Prediction Reversibly in Multisite Samples of Young Healthy Adults.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023
    Article
  9. Article
  10. Article
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  12. Article
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  16. The pupillary light reflex (PLR) as a marker for the ability to work or drive - a feasibility study.Journal of occupational medicine and toxicology (London, England) · 2021
    Article
  17. Article
  18. Article
  19. Article
  20. Cortical astrocytes regulate ethanol consumption and intoxication in mice.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Eva-Maria ElmenhorstDepartment of Sleep and Human Factors Research, Institute of Aerospace Medicine, German Aerospace Center (DLR), 51170 Cologne, Germany; eva-maria.elmenhorst@dlr.de.
David ElmenhorstInstitute of Neuroscience and Medicine (INM-2), Forschungszentrum Jülich, 52425 Jülich, Germany.ORCID 0000-0001-6137-416X
Sibylle BenderothDepartment of Sleep and Human Factors Research, Institute of Aerospace Medicine, German Aerospace Center (DLR), 51170 Cologne, Germany.
Tina KrollInstitute of Neuroscience and Medicine (INM-2), Forschungszentrum Jülich, 52425 Jülich, Germany.
Andreas BauerInstitute of Neuroscience and Medicine (INM-2), Forschungszentrum Jülich, 52425 Jülich, Germany.
Daniel AeschbachDepartment of Sleep and Human Factors Research, Institute of Aerospace Medicine, German Aerospace Center (DLR), 51170 Cologne, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Trait-like differences in cognitive performance after sleep loss put some individuals more at risk than others, the basis of such disparities remaining largely unknown. Similarly, interindividual differences in impairment in response to alcohol intake have been observed. We tested whether performance impairments due to either acute or chronic sleep loss can be predicted by an individual's vulnerability to acute alcohol intake. Also, we used positron emission tomography (PET) to test whether acute alcohol infusion results in an up-regulation of cerebral A

Indexed as

Alcohol DrinkingBrainCognitive DysfunctionPositron-Emission TomographyQuantitative Trait, HeritableReceptor, Adenosine A1Sleep DeprivationAdultHumansMaleReceptor, Adenosine A1adenosine receptorethanolhumansleep deprivationtrait vulnerabilities

Identifiers

PMID30012607
PMCPMC6077699

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.