Evidence map›Paper›PMID 30012560›Full record

ArticleGenetics2018

A Hippo Pathway-Related GCK Controls Both Sexual and Vegetative Developmental Processes in the Fungus

Daria Radchenko, Ines Teichert, Stefanie Pöggeler, Ulrich Kück

Open access · bronzeAbstract read
In one paragraph

Article in Genetics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 26 citations in OpenAlex.

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  6. STRIPAK, a fundamental signaling hub of eukaryotic development.Microbiology and molecular biology reviews : MMBR · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Daria RadchenkoLehrstuhl für Allgemeine und Molekulare Botanik, Ruhr-Universität Bochum, 44780, Germany.
Ines TeichertLehrstuhl für Allgemeine und Molekulare Botanik, Ruhr-Universität Bochum, 44780, Germany.ORCID 0000-0002-2993-6756
Stefanie PöggelerGenetik Eukaryotischer Mikroorganismen, Institut für Mikrobiologie und Genetik, Universität Göttingen, 37077, Germany.ORCID 0000-0002-6842-4489
Ulrich KückLehrstuhl für Allgemeine und Molekulare Botanik, Ruhr-Universität Bochum, 44780, Germany ulrich.kueck@rub.de.
Ruhr University Bochum · DEGenetikum · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The supramolecular striatin-interacting phosphatases and kinases (STRIPAK) complex is conserved from yeast to human, and regulates a variety of key biological processes. In animals, this complex consists of the scaffold protein striatin, the protein phosphatase 2A, and kinases, such as germinal center kinase (GCK) III and GCKIV family members, as well as other associated proteins. The STRIPAK complex was identified as a negative regulator of the Hippo pathway, a large eukaryotic signaling network with a core composed of a GCK and a nuclear Dbf2-related kinase. The signaling architecture of the Hippo core resembles the fungal septation initiation network (SIN) that regulates cytokinesis in fission yeast as well as septation in filamentous fungi. In the filamentous model fungus

Indexed as

Amino Acid SequenceFruiting Bodies, FungalFungal ProteinsGerminal Center KinasesHyphaePhylogenyProtein Phosphatase 2Protein Serine-Threonine KinasesSignal TransductionSordarialesFungal ProteinsGerminal Center KinasesProtein Phosphatase 2Protein Serine-Threonine Kinasesfungal sexual developmentgerminal center kinaseHippo pathwayseptationSordaria macrosporaSTRIPAK

Identifiers

PMID30012560
PMCPMC6116960
OpenAlexW2884170199

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.