Evidence map›Paper›PMID 30012180›Full record

ArticleTrials2018

Effect of transcranial direct current stimulation associated with hypocaloric diet on weight loss and metabolic profile in overweight or obesity: study protocol for a double-blind, randomized controlled clinical trial.

Carina de Araujo, Raquel Crespo Fitz, Daniela Albugeri Nogara, Pedro Schestatsky, Fernando Gerchman

Registry-linked trialAbstract readClinical Trial Protocol
PubMed Full text at PMC Publisher
In one paragraph

Article in Trials, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02683902 (The Effect of Hypocaloric Diet Associated With tDCS on Weight Loss and Metabolic Profile), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02683902 naunknown statusnot on this map

The Effect of Hypocaloric Diet Associated With tDCS on Weight Loss and Metabolic Profile: a Pilot, Double Blind, Randomized, Placebo-controlled Study

TypeinterventionalSponsorHospital de Clinicas de Porto AlegreRan2016 to 2018Enrolled20ConditionsPrediabetes, Obesity, Weight Loss, DiabetesArmsActive tDCS, Hypocaloric diet, Sham tDCS
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Non-invasive brain stimulation for osteoarthritis.Frontiers in aging neuroscience · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Carina de AraujoPostgraduate Program in Medical Science: Endocrinology, Universidade Federal do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil. carinanutri@hotmail.com.ORCID http://orcid.org/0000-0001-5841-0465
Raquel Crespo FitzPostgraduate Program in Medical Science: Endocrinology, Universidade Federal do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil.
Daniela Albugeri NogaraPostgraduate Program in Medical Science: Endocrinology, Universidade Federal do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil.
Pedro SchestatskyNeurology Service, Hospital de Clinicas de Porto Alegre, Universidade Federal do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil.
Fernando GerchmanEndocrine Division, Hospital de Clinicas de Porto Alegre, Universidade Federal do Rio Grande do Sul, Rua Ramiro Barcelos 2350, Anexo, 4° andar, Porto Alegre, Rio Grande do Sul, CEP: 90035-003, Brazil.

Funding

Associação Fundo de Incentivo à Pesquisa 150119Associação Fundo de Incentivo à Pesquisa 160417
6 · The paper itself

Abstract

backgroundDietary interventions have limited success in promoting sustainable weight loss; new treatments allowing better compliance with hypocaloric diets should be developed. The aim of this trial is to describe the effects of a protocol combining repetitive active transcranial direct current stimulation (tDCS) with a hypocaloric diet on weight loss and food consumption in overweight or obese adults. METHODS/

designOverweight or obese adults between 20 and 50 years of age with stable weight over the last 4 months will be selected for a 4-week randomized clinical trial of fixed-dose tDCS (20 sessions; 5 consecutive weekdays/wk, 2 mA, 20 minutes) over the right dorsolateral prefrontal cortex associated with a weight loss diet. The subjects will be randomly assigned in a 1:1 ratio and stratified by sex to active tDCS + diet or sham tDCS + diet. The study will be conducted at the Endocrine and Metabolism Unit of the Hospital de Clínicas de Porto Alegre, Brazil. The primary outcome is weight loss. Energy and macronutrient consumption, as well as adherence to the diet, will be assessed using 3-day weighed dietary records. Changes in blood glucose and plasma insulin will be assessed, and participants will complete self-report questionnaires to assess changes in mood and food behavior. All analyses will be done on a per-protocol and intention-to-treat basis. DISCUSSION: This study explores the potential role of tDCS as an adjunctive treatment with a hypocaloric diet for obesity management.

trial registrationClinicalTrials.gov , NCT02683902 . Registered on 11 January 2016.

Indexed as

Basal MetabolismDiet, ReducingRandomized Controlled Trials as TopicWeight LossAdultBlood GlucoseData Interpretation, StatisticalDouble-Blind MethodFemaleHumansInsulin ResistanceMaleMiddle AgedObesityOverweightTranscranial Direct Current StimulationBlood GlucoseClinical trialHypocaloric dietNeuromodulationObesityTranscranial direct current stimulationWeight loss

Identifiers

PMID30012180
PMCPMC6048812

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.