Evidence map›Paper›PMID 30012169›Full record

Observational studyHealth and quality of life outcomes2018

Physical frailty characteristics have a differential impact on symptoms as measured by the CAT score: an observational study.

Francesc Medina-Mirapeix, Roberto Bernabeu-Mora, Luz María Giménez-Giménez, Pilar Escolar-Reina, Mariano Gacto-Sánchez, Silvana Loana de Oliveira-Sousa

Open access · goldAbstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Health and quality of life outcomes, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 5 pooled it
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 5 syntheses or guidelines pooled it, 23 citations in OpenAlex.

  1. Pooled it
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  6. Article
  7. Review
  8. Observational
  9. Article
  10. Article
  11. Pathobiology of frailty in lung disease.Translational research : the journal of laboratory and clinical medicine · 2020
    Review
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Francesc Medina-MirapeixDepartment of Physical Therapy, University of Murcia, Murcia, Spain.
Roberto Bernabeu-MoraDivision of Pneumology, Department of Physical Therapy, Hospital Morales Meseguer, University of Murcia, Avda, Marqués de los Velez s/n, 30008, Murcia, Spain. rbernabeumora@hotmail.com.
Luz María Giménez-GiménezDivision of Clinical Psychology, Hospital Morales Meseguer, Murcia, Spain.
Pilar Escolar-ReinaDepartment of Physical Therapy, University of Murcia, Murcia, Spain.
Mariano Gacto-SánchezDepartment of Physical Therapy, EUSES University of Girona, Girona, Spain.
Silvana Loana de Oliveira-SousaCentre for Translational Research in Physiotherapy, Department of Pathology and Surgery, Miguel Hernández University (Elche), Alicante, Spain.
Universidad de Murcia · ESHospital General Universitario Morales Meseguer · ESUniversitat de Miguel Hernández d'Elx · ESUniversity of Girona · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe physical frailty status affects the health status of patients with chronic obstructive pulmonary disease (COPD). The objective was to determine if the individual physical frailty characteristics have a differential impact on the CAT score.

methodsThis observational study included 137 patients with stable COPD. Physical frailty was measured with unintentional weight loss, low physical activity, exhaustion, slow walking speed and low grip strength and health status assessed with the COPD Assessment test (CAT). The following variables were evaluated as potential determinants of CAT: sex, age, body mass index, smoking, dyspnea, exacerbations, comorbidities, %FEV1, %FVC, anxiety and depression.

resultsThe prevalence of characteristics for individual frailty was as follows: low grip strength, 60.6%; low physical activity, 27.0%; exhaustion, 19.7%; slow walking speed, 9.5%; and unintentional weight loss, 7.3%. A total of 17.5% of the patients were non-frail, 73.7% were pre-frail and only 8.7% were frail. One of the five frailty characteristics, exhaustion (adjusted β coefficient 5.12 [standard error = 1.27], p = 0.001) was an independent determinant of CAT score in the final regression model which was adjusted by other independent determinants of CAT (dyspnea, exacerbations and anxiety).

conclusionsDue to the fact that exhaustion is a frequent and relevant psychological symptom on CAT score of patients with COPD, interventions should reduce that stress. Future research should explore how exhaustion persists or remits over time.

Indexed as

Health StatusAgedBody Mass IndexComorbidityDepressionFatigueFemaleFrail ElderlyFrailtyHumansMaleMiddle AgedPrevalencePulmonary Disease, Chronic ObstructiveQuality of LifeSmoking

Identifiers

PMID30012169
PMCPMC6048765
OpenAlexW2884941579

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.